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UniProtKB/Swiss-Prot entry Q9LKL2


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name APRR1_ARATH
Primary accession number Q9LKL2
Secondary accession number Q9M4B7
Integrated into Swiss-Prot on September 27, 2004
Sequence was last modified on October 1, 2000 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 58)
Name and origin of the protein
Protein name Two-component response regulator-like APRR1
Synonyms Pseudo-response regulator 1
Timing of CAB expression 1
ABI3-interacting protein 1
Gene name
Name: APRR1
Synonyms: AIP1, TOC1
OrderedLocusNames: At5g61380
ORFNames: MFB13.16
From
Arabidopsis thaliana (Mouse-ear cress) [TaxID: 3702] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE, CHARACTERIZATION, AND GENE FAMILY.
STRAIN=cv. Columbia;
PubMed=10945350 [NCBI, ExPASy, EBI, Israel, Japan]
Makino S., Kiba T., Imamura A., Hanaki N., Nakamura A., Suzuki T., Taniguchi M., Ueguchi C., Sugiyama T., Mizuno T.;
"Genes encoding pseudo-response regulators: insight into His-to-Asp phosphorelay and circadian rhythm in Arabidopsis thaliana.";
Plant Cell Physiol. 41:791-803(2000).
[2]
NUCLEOTIDE SEQUENCE [MRNA], AND MUTAGENESIS OF ALA-562.
STRAIN=cv. Columbia;
DOI=10.1126/science.289.5480.768; PubMed=10926537 [NCBI, ExPASy, EBI, Israel, Japan]
Strayer C., Oyama T., Schultz T.F., Raman R., Somers D.E., Mas P., Panda S., Kreps J.A., Kay S.A.;
"Cloning of the Arabidopsis clock gene TOC1, an autoregulatory response regulator homolog.";
Science 289:768-771(2000).
[3]
NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, AND INTERACTION WITH ABI3.
STRAIN=cv. Landsberg erecta;
PubMed=10743655 [NCBI, ExPASy, EBI, Israel, Japan]
Kurup S., Jones H.D., Holdsworth M.J.;
"Interactions of the developmental regulator ABI3 with proteins identified from developing Arabidopsis seeds.";
Plant J. 21:143-155(2000).
[4]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
DOI=10.1093/dnares/5.1.41; PubMed=9628582 [NCBI, ExPASy, EBI, Israel, Japan]
Sato S., Kaneko T., Kotani H., Nakamura Y., Asamizu E., Miyajima N., Tabata S.;
"Structural analysis of Arabidopsis thaliana chromosome 5. IV. Sequence features of the regions of 1,456,315 bp covered by nineteen physically assigned P1 and TAC clones.";
DNA Res. 5:41-54(1998).
[5]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=cv. Columbia;
DOI=10.1126/science.1088305; PubMed=14593172 [NCBI, ExPASy, EBI, Israel, Japan]
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
"Empirical analysis of transcriptional activity in the Arabidopsis genome.";
Science 302:842-846(2003).
[6]
FUNCTION.
DOI=10.1093/pcp/pcd043; PubMed=11100772 [NCBI, ExPASy, EBI, Israel, Japan]
Matsushika A., Makino S., Kojima M., Mizuno T.;
"Circadian waves of expression of the APRR1/TOC1 family of pseudo-response regulators in Arabidopsis thaliana: insight into the plant circadian clock.";
Plant Cell Physiol. 41:1002-1012(2000).
[7]
INDUCTION.
DOI=10.1126/science.1061320; PubMed=11486091 [NCBI, ExPASy, EBI, Israel, Japan]
Alabadi D., Oyama T., Yanovsky M.J., Harmon F.G., Mas P., Kay S.A.;
"Reciprocal regulation between TOC1 and LHY/CCA1 within the Arabidopsis circadian clock.";
Science 293:880-883(2001).
[8]
INTERACTION WITH ADO1 AND ADO2.
DOI=10.1093/jxb/erh226; PubMed=15310821 [NCBI, ExPASy, EBI, Israel, Japan]
Yasuhara M., Mitsui S., Hirano H., Takanabe R., Tokioka Y., Ihara N., Komatsu A., Seki M., Shinozaki K., Kiyosue T.;
"Identification of ASK and clock-associated proteins as molecular partners of LKP2 (LOV kelch protein 2) in Arabidopsis.";
J. Exp. Bot. 55:2015-2027(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AB041530; BAA94547.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AF272039; AAF86252.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AJ251086; CAB75508.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AB010073; BAB08493.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY094393; AAM19772.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BT005816; AAO64751.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T52075; T52075.
T52076; T52076.
RefSeq NP_200946.1; -.
UniGene At.21919
3D structure databases
ModBase Q9LKL2.
Protein-protein interaction databases
IntAct Q9LKL2; -.
Organism-specific databases
GeneFarm 4313; 437.
TAIR At5g61380; -.
Gene expression databases
ArrayExpress Q9LKL2; -.
GermOnline AT5G61380; Arabidopsis thaliana.
Ontologies
GO
GO:0005515; Molecular function: protein binding (inferred from physical interaction from IntAct).
GO:0030528; Molecular function: transcription regulator activity (traceable author statement from TAIR).
QuickGo view.
Family and domain databases
InterPro IPR010402; CCT.
IPR001789; Sig_transdc_resp-reg_receiver.
Graphical view of domain structure.
Pfam PF06203; CCT; 1.
PF00072; Response_reg; 1.
Pfam graphical view of domain structure.
ProDom PD000039; Response_reg; 1.
[Domain structure / List of seq. sharing at least 1 domain]
SMART SM00448; REC; 1.
SMART graphical view of domain structure.
PROSITE PS51017; CCT; 1.
PS50110; RESPONSE_REGULATORY; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q9LKL2.
Genome annotation databases
GeneID 836259; -.
GenomeReviews BA000015_GR; AT5G61380.
KEGG ath:AT5G61380; -.
NMPDR fig|3702.1.peg.28159; -.
Other
ProtoNet Q9LKL2.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Coiled coil; Complete proteome; Nucleus; Transcription; Transcription regulation; Two-component regulatory system.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   618  618     Two-component response regulator-like APRR1. PRO_0000081435
DOMAIN   20   138  119     Response regulatory. 
DOMAIN   533   575  43     CCT. 
COILED   588   610  23     Potential. 
COMPBIAS   595   605  11     Poly-Glu. 
MUTAGEN   562   562        A->V: In toc1-1; causes shortened circadian rhythms in light-grown plants. 
CONFLICT   126   126        R -> L (in Ref. 2; CAB75508). 
Sequence information
Length: 618 AA [This is the length of the unprocessed precursor] Molecular weight: 69195 Da [This is the MW of the unprocessed precursor] CRC64: EDBE0AA0B7FAB61E [This is a checksum on the sequence]
        10         20         30         40         50         60 
MDLNGECKGG DGFIDRSRVR ILLCDNDSTS LGEVFTLLSE CSYQVTAVKS ARQVIDALNA 

        70         80         90        100        110        120 
EGPDIDIILA EIDLPMAKGM KMLRYITRDK DLRRIPVIMM SRQDEVPVVV KCLKLGAADY 

       130        140        150        160        170        180 
LVKPLRTNEL LNLWTHMWRR RRMLGLAEKN MLSYDFDLVG SDQSDPNTNS TNLFSDDTDD 

       190        200        210        220        230        240 
RSLRSTNPQR GNLSHQENEW SVATAPVHAR DGGLGADGTA TSSLAVTAIE PPLDHLAGSH 

       250        260        270        280        290        300 
HEPMKRNSNP AQFSSAPKKS RLKIGESSAF FTYVKSTVLR TNGQDPPLVD GNGSLHLHRG 

       310        320        330        340        350        360 
LAEKFQVVAS EGINNTKQAR RATPKSTVLR TNGQDPPLVN GNGSHHLHRG AAEKFQVVAS 

       370        380        390        400        410        420 
EGINNTKQAH RSRGTEQYHS QGETLQNGAS YPHSLERSRT LPTSMESHGR NYQEGNMNIP 

       430        440        450        460        470        480 
QVAMNRSKDS SQVDGSGFSA PNAYPYYMHG VMNQVMMQSA AMMPQYGHQI PHCQPNHPNG 

       490        500        510        520        530        540 
MTGYPYYHHP MNTSLQHSQM SLQNGQMSMV HHSWSPAGNP PSNEVRVNKL DRREEALLKF 

       550        560        570        580        590        600 
RRKRNQRCFD KKIRYVNRKR LAERRPRVKG QFVRKMNGVN VDLNGQPDSA DYDDEEEEEE 

       610 
EEEEENRDSS PQDDALGT 

Q9LKL2 in FASTA format

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