[1]
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NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 208-225 AND 262-272, SUBCELLULAR LOCATION, PHOSPHORYLATION, AND INTERACTION WITH ADPRT.
DOI=10.1016/S0014-5793(01)02180-9; PubMed=11248244 [NCBI, ExPASy, EBI, Israel, Japan]
Schweiger M.,
Hennig K.,
Lerner F.,
Niere M.,
Hirsch-Kauffmann M.,
Specht T.,
Weise C.,
Oei S.L.,
Ziegler M.;
"Characterization of recombinant human nicotinamide mononucleotide adenylyl transferase (NMNAT), a nuclear enzyme essential for NAD synthesis.";
FEBS Lett. 492:95-100(2001).
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[2]
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NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 238-250 AND 262-272, COFACTOR, AND TISSUE SPECIFICITY.
TISSUE=Placenta;
DOI=10.1074/jbc.M008700200; PubMed=11027696 [NCBI, ExPASy, EBI, Israel, Japan]
Emanuelli M.,
Carnevali F.,
Saccucci F.,
Pierella F.,
Amici A.,
Raffaelli N.,
Magni G.;
"Molecular cloning, chromosomal localization, tissue mRNA levels, bacterial expression, and enzymatic properties of human NMN adenylyltransferase.";
J. Biol. Chem. 276:406-412(2001).
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[3]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], AND TISSUE SPECIFICITY.
DOI=10.1016/S0378-1119(02)00394-3; PubMed=11891043 [NCBI, ExPASy, EBI, Israel, Japan]
Fernando F.S.,
Conforti L.,
Tosi S.,
Smith A.D.,
Coleman M.P.;
"Human homologue of a gene mutated in the slow Wallerian degeneration (C57BL/Wld(s)) mouse.";
Gene 284:23-29(2002).
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[4]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
DOI=10.1038/ng1285; PubMed=14702039 [NCBI, ExPASy, EBI, Israel, Japan]
Ota T.,
Suzuki Y.,
Nishikawa T.,
Otsuki T.,
Sugiyama T.,
Irie R.,
Wakamatsu A.,
Hayashi K.,
Sato H.,
Nagai K.,
Kimura K.,
Makita H.,
Sekine M.,
Obayashi M.,
Nishi T.,
Shibahara T.,
Tanaka T.,
Ishii S.,
Yamamoto J., ![]()
Saito K.,
Kawai Y.,
Isono Y.,
Nakamura Y.,
Nagahari K.,
Murakami K.,
Yasuda T.,
Iwayanagi T.,
Wagatsuma M.,
Shiratori A.,
Sudo H.,
Hosoiri T.,
Kaku Y.,
Kodaira H.,
Kondo H.,
Sugawara M.,
Takahashi M.,
Kanda K.,
Yokoi T.,
Furuya T.,
Kikkawa E.,
Omura Y.,
Abe K.,
Kamihara K.,
Katsuta N.,
Sato K.,
Tanikawa M.,
Yamazaki M.,
Ninomiya K.,
Ishibashi T.,
Yamashita H.,
Murakawa K.,
Fujimori K.,
Tanai H.,
Kimata M.,
Watanabe M.,
Hiraoka S.,
Chiba Y.,
Ishida S.,
Ono Y.,
Takiguchi S.,
Watanabe S.,
Yosida M.,
Hotuta T.,
Kusano J.,
Kanehori K.,
Takahashi-Fujii A.,
Hara H.,
Tanase T.-O.,
Nomura Y.,
Togiya S.,
Komai F.,
Hara R.,
Takeuchi K.,
Arita M.,
Imose N.,
Musashino K.,
Yuuki H.,
Oshima A.,
Sasaki N.,
Aotsuka S.,
Yoshikawa Y.,
Matsunawa H.,
Ichihara T.,
Shiohata N.,
Sano S.,
Moriya S.,
Momiyama H.,
Satoh N.,
Takami S.,
Terashima Y.,
Suzuki O.,
Nakagawa S.,
Senoh A.,
Mizoguchi H.,
Goto Y.,
Shimizu F.,
Wakebe H.,
Hishigaki H.,
Watanabe T.,
Sugiyama A.,
Takemoto M.,
Kawakami B.,
Yamazaki M.,
Watanabe K.,
Kumagai A.,
Itakura S.,
Fukuzumi Y.,
Fujimori Y.,
Komiyama M.,
Tashiro H.,
Tanigami A.,
Fujiwara T.,
Ono T.,
Yamada K.,
Fujii Y.,
Ozaki K.,
Hirao M.,
Ohmori Y.,
Kawabata A.,
Hikiji T.,
Kobatake N.,
Inagaki H.,
Ikema Y.,
Okamoto S.,
Okitani R.,
Kawakami T.,
Noguchi S.,
Itoh T.,
Shigeta K.,
Senba T.,
Matsumura K.,
Nakajima Y.,
Mizuno T.,
Morinaga M.,
Sasaki M.,
Togashi T.,
Oyama M.,
Hata H.,
Watanabe M.,
Komatsu T.,
Mizushima-Sugano J.,
Satoh T.,
Shirai Y.,
Takahashi Y.,
Nakagawa K.,
Okumura K.,
Nagase T.,
Nomura N.,
Kikuchi H.,
Masuho Y.,
Yamashita R.,
Nakai K.,
Yada T.,
Nakamura Y.,
Ohara O.,
Isogai T.,
Sugano S.;
"Complete sequencing and characterization of 21,243 full-length human cDNAs.";
Nat. Genet. 36:40-45(2004).
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[5]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Eye;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
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[6]
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SUBCELLULAR LOCATION.
DOI=10.1074/jbc.M300073200; PubMed=12574164 [NCBI, ExPASy, EBI, Israel, Japan]
Zhang X.,
Kurnasov O.V.,
Karthikeyan S.,
Grishin N.V.,
Osterman A.L.,
Zhang H.;
"Structural characterization of a human cytosolic NMN/NaMN adenylyltransferase and implication in human NAD biosynthesis.";
J. Biol. Chem. 278:13503-13511(2003).
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[7]
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BIOPHYSICOCHEMICAL PROPERTIES, AND SUBCELLULAR LOCATION.
DOI=10.1074/jbc.M508660200; PubMed=16118205 [NCBI, ExPASy, EBI, Israel, Japan]
Berger F.,
Lau C.,
Dahlmann M.,
Ziegler M.;
"Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms.";
J. Biol. Chem. 280:36334-36341(2005).
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[8]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-119, AND MASS SPECTROMETRY.
TISSUE=Epithelium;
DOI=10.1016/j.cell.2006.09.026; PubMed=17081983 [NCBI, ExPASy, EBI, Israel, Japan]
Olsen J.V.,
Blagoev B.,
Gnad F.,
Macek B.,
Kumar C.,
Mortensen P.,
Mann M.;
"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.";
Cell 127:635-648(2006).
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[9]
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FUNCTION, BIOPHYSICOCHEMICAL PROPERTIES, ENZYME REGULATION, AND COFACTOR.
DOI=10.1021/bi6023379; PubMed=17402747 [NCBI, ExPASy, EBI, Israel, Japan]
Sorci L.,
Cimadamore F.,
Scotti S.,
Petrelli R.,
Cappellacci L.,
Franchetti P.,
Orsomando G.,
Magni G.;
"Initial-rate kinetics of human NMN-adenylyltransferases: substrate and metal ion specificity, inhibition by products and multisubstrate analogues, and isozyme contributions to NAD+ biosynthesis.";
Biochemistry 46:4912-4922(2007).
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[10]
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X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS) OF 5-278.
DOI=10.1016/S0014-5793(02)02556-5; PubMed=11959140 [NCBI, ExPASy, EBI, Israel, Japan]
Werner E.,
Ziegler M.,
Lerner F.,
Schweiger M.,
Heinemann U.;
"Crystal structure of human nicotinamide mononucleotide adenylyltransferase in complex with NMN.";
FEBS Lett. 516:239-244(2002).
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[11]
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X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS).
DOI=10.1074/jbc.M111589200; PubMed=11751893 [NCBI, ExPASy, EBI, Israel, Japan]
Garavaglia S.,
D'Angelo I.,
Emanuelli M.,
Carnevali F.,
Pierella F.,
Magni G.,
Rizzi M.;
"Structure of human NMN adenylyltransferase. A key nuclear enzyme for NAD homeostasis.";
J. Biol. Chem. 277:8524-8530(2002).
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[12]
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X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS).
DOI=10.1074/jbc.M111469200; PubMed=11788603 [NCBI, ExPASy, EBI, Israel, Japan]
Zhou T.,
Kurnasov O.,
Tomchick D.R.,
Binns D.D.,
Grishin N.V.,
Marquez V.E.,
Osterman A.L.,
Zhang H.;
"Structure of human nicotinamide/nicotinic acid mononucleotide adenylyltransferase. Basis for the dual substrate specificity and activation of the oncolytic agent tiazofurin.";
J. Biol. Chem. 277:13148-13154(2002).
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