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UniProtKB/Swiss-Prot entry Q92914

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name FGF11_HUMAN
Primary accession number Q92914
Secondary accession number Q2YDX8
Integrated into Swiss-Prot on November 1, 1997
Sequence was last modified on February 1, 1997 (Sequence version 1)
Annotations were last modified on    June 16, 2009 (Entry version 72)
Name and origin of the protein
Protein name Fibroblast growth factor 11
Synonyms FGF-11
Fibroblast growth factor homologous factor 3
FHF-3
Gene name
Name: FGF11
Synonyms: FHF3
From
Homo sapiens (Human) [TaxID: 9606] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
Protein existence 2: Evidence at transcript level;
References
[1]
 NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Retina;
DOI=10.1073/pnas.93.18.9850; PubMed=8790420 [NCBI, ExPASy, EBI, Israel, Japan]
Smallwood P.M., Munoz-Sanjuan I., Tong P., Macke J.P., Hendry S.H., Gilbert D.J., Copeland N.G., Jenkins N.A., Nathans J.;
"Fibroblast growth factor (FGF) homologous factors: new members of the FGF family implicated in nervous system development.";
Proc. Natl. Acad. Sci. U.S.A. 93:9850-9857(1996).
[2]
 NUCLEOTIDE SEQUENCE [MRNA].
Han C., Zhang B., Zhou Y., Peng X., Yuan J., Qiang B.;
Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases.
[3]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND VARIANT GLY-163.
NIEHS SNPs program;
Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
[4]
 NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Brain, and Skin;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
U66199; AAB18915.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY049782; AAL15439.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY094623; AAM11871.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BC032502; AAH32502.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BC108265; AAI08266.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
IPI IPI00024252; -.
RefSeq NP_004103.1; -.
UniGene Hs.330386
3D structure databases
HSSP P08620; 1IJT. [HSSP ENTRY / PDB]
ModBase Q92914.
Organism-specific databases
GeneCards GC17P007283; -.
H-InvDB HIX0079953; -.
HGNC HGNC:3667; FGF11.
GenAtlas FGF11.
MIM 601514; gene. [NCBI / EBI]
PharmGKB PA28107; -.
Gene expression databases
ArrayExpress Q92914; -.
Bgee Q92914; -.
CleanEx HS_FGF11; -.
GermOnline ENSG00000161958; Homo sapiens.
Ontologies
GO
GO:0008083; Molecular function: growth factor activity (traceable author statement from ProtInc).
GO:0007267; Biological process: cell-cell signaling (traceable author statement from ProtInc).
GO:0007399; Biological process: nervous system development (traceable author statement from ProtInc).
GO:0007165; Biological process: signal transduction (traceable author statement from ProtInc).
QuickGo view.
Family and domain databases
InterPro IPR002209; GF_heparin_bd.
IPR002348; IL1_HBGF.
Graphical view of domain structure.
PANTHER PTHR11486; IL1_HBGF; 1.
Pfam PF00167; FGF; 1.
Pfam graphical view of domain structure.
PRINTS PR00263; HBGFFGF.
PR00262; IL1HBGF.
ProDom PD000831; IL1_HBGF; 1.
[Domain structure / List of seq. sharing at least 1 domain]
SMART SM00442; FGF; 1.
SMART graphical view of domain structure.
PROSITE PS00247; HBGF_FGF; 1.
Proteomic databases
PRIDE Q92914; -.
Genome annotation databases
Ensembl ENSG00000161958; Homo sapiens. [Contig view]
GeneID 2256; -.
KEGG hsa:2256; -.
Phylogenomic databases
HOGENOM Q92914; -.
HOVERGEN Q92914; -.
OMA Q92914; CERPARQ.
Other
NextBio 9139; -.
SOURCE FGF11; Homo sapiens.
ProtoNet Q92914.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Growth factor; Polymorphism.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   225  225     Fibroblast growth factor 11. PRO_0000147602
VARIANT   163   163  1     R -> G. VAR_018886 
Sequence information
Length: 225 AA [This is the length of the unprocessed precursor] Molecular weight: 25005 Da [This is the MW of the unprocessed precursor] CRC64: 3176FF22053072DC [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MAALASSLIR QKREVREPGG SRPVSAQRRV CPRGTKSLCQ KQLLILLSKV RLCGGRPARP 

        70         80         90        100        110        120 
DRGPEPQLKG IVTKLFCRQG FYLQANPDGS IQGTPEDTSS FTHFNLIPVG LRVVTIQSAK 

       130        140        150        160        170        180 
LGHYMAMNAE GLLYSSPHFT AECRFKECVF ENYYVLYASA LYRQRRSGRA WYLGLDKEGQ 

       190        200        210        220 
VMKGNRVKKT KAAAHFLPKL LEVAMYQEPS LHSVPEASPS SPPAP
Q92914 in FASTA format

View entry in raw text format (no links)
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