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UniProtKB/Swiss-Prot entry Q91ZB7


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name MRGRE_MOUSE
Primary accession number Q91ZB7
Secondary accession number Q711I9
Integrated into Swiss-Prot on August 31, 2004
Sequence was last modified on December 1, 2001 (Sequence version 1)
Annotations were last modified on    June 16, 2009 (Entry version 49)
Name and origin of the protein
Protein name Mas-related G-protein coupled receptor member E
Synonym Evolutionary breakpoint transcript 3 protein
Gene name
Name: Mrgpre
Synonyms: Ebrt3, Mrge
From
Mus musculus (Mouse) [TaxID: 10090] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE.
STRAIN=C57BL/6;
DOI=10.1016/S0092-8674(01)00483-4; PubMed=11551509 [NCBI, ExPASy, EBI, Israel, Japan]
Dong X., Han S.-K., Zylka M.J., Simon M.I., Anderson D.J.;
"A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons.";
Cell 106:619-632(2001).
[2]
NUCLEOTIDE SEQUENCE.
STRAIN=C57BL/6;
Engemann S., Stroedicke M., Meguro M., Franck O., Kalscheuer V., Oshimura M., Walter J.;
"An evolutinary breakpoint region borders the imprinted Beckwith-Wiedemann syndrome (BWS) region.";
Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=C57BL/6J;
TISSUE=Head;
DOI=10.1126/science.1112014; PubMed=16141072 [NCBI, ExPASy, EBI, Israel, Japan]
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J., Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
"The transcriptional landscape of the mammalian genome.";
Science 309:1559-1563(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AY042210; AAK91801.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AJ320231; CAC86257.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AK048528; BAC33361.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
IPI IPI00131025; -.
RefSeq NP_780743.1; -.
UniGene Mm.183561
3D structure databases
ModBase Q91ZB7.
Protein family/group databases
GPCRDB Q91ZB7; MRGRE_MOUSE.
Organism-specific databases
MGI MGI:2441884; Mrgpre.
Gene expression databases
ArrayExpress Q91ZB7; -.
Bgee Q91ZB7; -.
CleanEx MM_MRGPRE; -.
GermOnline ENSMUSG00000048965; Mus musculus.
Ontologies
GO
GO:0016021; Cellular component: integral to membrane (inferred from electronic annotation from UniProtKB-KW).
GO:0005886; Cellular component: plasma membrane (inferred from electronic annotation from UniProtKB-SubCell).
GO:0004930; Molecular function: G-protein coupled receptor activity (inferred from electronic annotation from UniProtKB-KW).
GO:0007186; Biological process: G-protein coupled receptor protein signaling pathway (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR000276; 7TM_GPCR_Rhodpsn.
IPR017452; GPCR_Rhodpsn_supfam.
Graphical view of domain structure.
Pfam PF00001; 7tm_1; 1.
Pfam graphical view of domain structure.
PRINTS PR00237; GPCRRHODOPSN.
PROSITE PS00237; G_PROTEIN_RECEP_F1_1; FALSE_NEG.
PS50262; G_PROTEIN_RECEP_F1_2; 1.
PROSITE graphical view of domain structure (profiles).
Genome annotation databases
Ensembl ENSMUSG00000048965; Mus musculus. [Contig view]
GeneID 244238; -.
KEGG mmu:244238; -.
Phylogenomic databases
HOGENOM Q91ZB7; -.
HOVERGEN Q91ZB7; -.
OMA Q91ZB7; DVACADL.
Other
NextBio 386209; -.
SOURCE Mrgpre; Mus musculus.
GPCRDB-Snakes Q91ZB7.
ProtoNet Q91ZB7.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Cell membrane; G-protein coupled receptor; Glycoprotein; Membrane; Receptor; Transducer; Transmembrane.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   310  310     Mas-related G-protein coupled receptor member E. PRO_0000069762
TOPO_DOM   1    22  22     Extracellular (Potential). 
TRANSMEM   23    43  21     1 (Potential). 
TOPO_DOM   44    60  17     Cytoplasmic (Potential). 
TRANSMEM   61    81  21     2 (Potential). 
TOPO_DOM   82    92  11     Extracellular (Potential). 
TRANSMEM   93   113  21     3 (Potential). 
TOPO_DOM   114   133  20     Cytoplasmic (Potential). 
TRANSMEM   134   154  21     4 (Potential). 
TOPO_DOM   155   174  20     Extracellular (Potential). 
TRANSMEM   175   195  21     5 (Potential). 
TOPO_DOM   196   213  18     Cytoplasmic (Potential). 
TRANSMEM   214   234  21     6 (Potential). 
TOPO_DOM   235   248  14     Extracellular (Potential). 
TRANSMEM   249   269  21     7 (Potential). 
TOPO_DOM   270   310  41     Cytoplasmic (Potential). 
CARBOHYD   20    20        N-linked (GlcNAc...) (Potential). 
CARBOHYD   237   237        N-linked (GlcNAc...) (Potential). 
Sequence information
Length: 310 AA [This is the length of the unprocessed precursor] Molecular weight: 34588 Da [This is the MW of the unprocessed precursor] CRC64: 9E44127DCB5E9370 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTSLSVHTDS PSTQGEMAFN LTILSLTELL SLGGLLGNGV ALWLLNQNVY RNPFSIYLLD 

        70         80         90        100        110        120 
VACADLIFLC CHMVAIIPEL LQDQLNFPEF VHISLTMLRF FCYIVGLSLL AAISTEQCLA 

       130        140        150        160        170        180 
TLFPAWYLCR RPRYLTTCVC ALIWVLCLLL DLLLSGACTQ FFGAPSYHLC DMLWLVVAVL 

       190        200        210        220        230        240 
LAALCCTMCV TSLLLLLRVE RGPERHQPRG FPTLVLLAVL LFLFCGLPFG IFWLSKNLSW 

       250        260        270        280        290        300 
HIPLYFYHFS FFMASVHSAA KPAIYFFLGS TPGQRFREPL RLVLQRALGD EAELGAGREA 

       310 
SQGGLVDMTV 

Q91ZB7 in FASTA format

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