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UniProtKB/Swiss-Prot entry Q8Z6G1


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ASTD_SALTI
Primary accession number Q8Z6G1
Secondary accession number Q7CA95
Integrated into Swiss-Prot on November 28, 2006
Sequence was last modified on November 28, 2006 (Sequence version 2)
Annotations were last modified on    November 4, 2008 (Entry version 43)
Name and origin of the protein
Protein name N-succinylglutamate 5-semialdehyde dehydrogenase
Synonyms EC 1.2.1.71
Succinylglutamic semialdehyde dehydrogenase
SGSD
Gene name
Name: astD
OrderedLocusNames: STY1809, t1184
From
Salmonella typhi [TaxID: 601] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Salmonella.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=CT18;
DOI=10.1038/35101607; PubMed=11677608 [NCBI, ExPASy, EBI, Israel, Japan]
Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J., Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M., Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A., Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T., Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A., Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A., Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S., Barrell B.G.;
"Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18.";
Nature 413:848-852(2001).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 700931 / Ty2;
DOI=10.1128/JB.185.7.2330-2337.2003; PubMed=12644504 [NCBI, ExPASy, EBI, Israel, Japan]
Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V., Kodoyianni V., Schwartz D.C., Blattner F.R.;
"Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and CT18.";
J. Bacteriol. 185:2330-2337(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AL627271; CAD02049.1; ALT_SEQ; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AE014613; AAO68840.1; ALT_SEQ; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_456207.1; -.
NP_804991.1; -.
3D structure databases
HSSP Q28399; 1O9J. [HSSP ENTRY / PDB]
ModBase Q8Z6G1.
Enzyme and pathway databases
BioCyc SENT209261:T1184-MON; -.
SENT220341:STY1809-MON; -.
Ontologies
GO
GO:0019544; Biological process: arginine catabolic process to glutamate (inferred from electronic annotation from HAMAP).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
HAMAP MF_01174; -; 1.
PBIL [Tree]
InterPro IPR016160; Ald_DHase_CS.
IPR015590; Aldehyde_DHase.
IPR017649; SuccinylGlu_semiald_DH_AstD.
Graphical view of domain structure.
PANTHER PTHR11699; Aldehyde_dehyd; 1.
Pfam PF00171; Aldedh; 1.
Pfam graphical view of domain structure.
PROSITE PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PS00687; ALDEHYDE_DEHYDR_GLU; 1.
BLOCKS Q8Z6G1.
ProtoNet Q8Z6G1.
Genome annotation databases
GeneID 1070602; -.
1248178; -.
GenomeReviews AL513382_GR; STY1809.
AE014613_GR; t1184.
KEGG stt:t1184; -.
sty:STY1809; -.
Phylogenomic databases
HOGENOM Q8Z6G1; -.
Genome annotation databases
CMR Q8Z6G1; STY1809.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Arginine metabolism; Complete proteome; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   492  492     N-succinylglutamate 5-semialdehyde dehydrogenase. PRO_0000262421
NP_BIND   220   225  6     NAD (By similarity). 
ACT_SITE   243   243        By similarity. 
ACT_SITE   277   277        By similarity. 
Sequence information
Length: 492 AA [This is the length of the unprocessed precursor] Molecular weight: 53212 Da [This is the MW of the unprocessed precursor] CRC64: 037656582563AF41 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTLWINGDWI TGQGERRRKT NPVSEEILWQ GNDADAAQVA EACQAARAAF PRWARQPFAA 

        70         80         90        100        110        120 
RQAIVEKFSV LLEAHKADLT EVIARETGKP RWEAATEVTA MINKIAISIK AYHARTGEQK 

       130        140        150        160        170        180 
SELVDGAATL RHRPHGVLAV FGPYNFPGHL PNGHIVPALL AGNTLIFKPS ELTPWTGETV 

       190        200        210        220        230        240 
IKLWERAGLP AGVLNLVQGG RETGQALSSL DDLDGLLFTG SASTGYQLHR QLSGQPEKIL 

       250        260        270        280        290        300 
ALEMGGNNPL IIEDATNMDA AVHLTLQSAF ITAGQRCTCA RRLLVKQGAQ GDAFLARLVD 

       310        320        330        340        350        360 
VAGRLQPGRW DDDPQPFIGG LISAQAAQHV MEAWRQREAL GGRTLLAPRK VKEGTSLLTP 

       370        380        390        400        410        420 
GIIELTGVAD VPDEEVFGPL LNVWRYAHFD EAIRLANNTR FGLSCGLVST DRAQFEQLLL 

       430        440        450        460        470        480 
EARAGIVNWN KPLTGAASTA PFGGVGASGN HRPSAWYAAD YCAWPMASLE SPELTLPATL 

       490 
SPGLDFSRRE AV 

Q8Z6G1 in FASTA format

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