FUNCTION: May perform analogous functions in iron detoxification and storage to that of animal ferritins.
COFACTOR: Binds 1 heme B (iron-protoporphyrin IX) group per dimer (By similarity).
SUBUNIT: Oligomer of 24 identical subunits (By similarity).
MISCELLANEOUS: The di-iron binding site functions as active site where iron ions are oxidized from Fe(2+) to Fe(3+) before they are stored (By similarity).
SIMILARITY: Belongs to the bacterioferritin family.
SIMILARITY: Contains 1 ferritin-like diiron domain.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AE014292; AAN33754.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

NP_699749.1; -.

3D structure databases

HSSP

P11056; 1BCF. [HSSP ENTRY / PDB]

ModBase

Q8FW95.

Enzyme and pathway databases

BioCyc

BSUI204722:BR_A0565-MON; -.

Ontologies

GO:0008199;	Molecular function: ferric iron binding (inferred from electronic annotation from InterPro).
GO:0016491;	Molecular function: oxidoreductase activity (inferred from electronic annotation from InterPro).
GO:0006879;	Biological process: cellular iron ion homeostasis (inferred from electronic annotation from UniProtKB-KW).
GO:0006826;	Biological process: iron ion transport (inferred from electronic annotation from InterPro).
QuickGo view.

Family and domain databases

InterPro

IPR002024; Bacterioferritin.
IPR009040; Ferritin-like.
IPR008331; Ferritin_Dps.
IPR012347; Ferritin_rel.
Graphical view of domain structure.

Gene3D

G3DSA:1.20.1260.10; Ferritin_rel; 1.

Pfam

PF00210; Ferritin; 1.
Pfam graphical view of domain structure.

PIRSF

PIRSF002560; Bacterioferritin; 1.

PRINTS

PR00601; BACFERRITIN.

ProDom

PD002269; Bacterioferritin; 1.
[Domain structure / List of seq. sharing at least 1 domain]

TIGRFAMs

TIGR00754; bfr; 1.

PROSITE

PS00549; BACTERIOFERRITIN; 1.
PS50905; FERRITIN_LIKE; 1.
PROSITE graphical view of domain structure (profiles).

Genome annotation databases

GeneID

1165004; -.

GenomeReviews

AE014292_GR; BRA0565.

KEGG

bms:BRA0565; -.

NMPDR

fig|204722.1.peg.2658; -.

TIGR

BRA0565; -.

Phylogenomic databases

HOGENOM

Q8FW95; -.

OMA

Q8FW95; WRKESIE.

Other

ProtoNet

Q8FW95.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Heme; Iron; Iron storage; Metal-binding.

Features

Feature table viewer

Feature aligner

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 161`	`161`	`Bacterioferritin.`	`PRO_0000192590`
`DOMAIN`	`1 145`	`145`	`Ferritin-like diiron.`
`METAL`	`18 18`		`Iron 1 (By similarity).`
`METAL`	`51 51`		`Iron 1 (By similarity).`
`METAL`	`51 51`		`Iron 2 (By similarity).`
`METAL`	`52 52`		`Iron (heme axial ligand) (By similarity).`
`METAL`	`54 54`		`Iron 1 (By similarity).`
`METAL`	`94 94`		`Iron 2 (By similarity).`
`METAL`	`127 127`		`Iron 1 (By similarity).`
`METAL`	`127 127`		`Iron 2 (By similarity).`
`METAL`	`130 130`		`Iron 2 (By similarity).`

Sequence information

Length: 161 AA [This is the length of the unprocessed precursor]

Molecular weight: 18640 Da [This is the MW of the unprocessed precursor]

CRC64: 1D30A44BE843DDCE [This is a checksum on the sequence]

        10         20         30         40         50         60 
MKGEPKVIER LNEALFLELG AVNQYWLHYR LLNDWGYTRL AKKEREESIE EMHHADKLID 

        70         80         90        100        110        120 
RIIFLEGFPN LQTVSPLRIG QNVKEVLEAD LKGEYDARAS YKESREICDK LGDYVSKQLF 

       130        140        150        160 
DELLADEEGH IDFLETQLDL LAKIGEERYG QLNAAPADEA E

Q8FW95 in FASTA format

View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools