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UniProtKB/Swiss-Prot entry Q8BVI5


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name STX16_MOUSE
Primary accession number Q8BVI5
Secondary accession numbers None
Integrated into Swiss-Prot on January 24, 2006
Sequence was last modified on January 24, 2006 (Sequence version 2)
Annotations were last modified on    February 10, 2009 (Entry version 46)
Name and origin of the protein
Protein name Syntaxin-16
Synonyms None
Gene name
Name: Stx16
From
Mus musculus (Mouse) [TaxID: 10090] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=C57BL/6J;
TISSUE=Medulla oblongata;
DOI=10.1126/science.1112014; PubMed=16141072 [NCBI, ExPASy, EBI, Israel, Japan]
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J., Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
"The transcriptional landscape of the mammalian genome.";
Science 309:1559-1563(2005).
[2]
PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-35, AND MASS SPECTROMETRY.
TISSUE=Brain cortex;
DOI=10.1074/mcp.M600046-MCP200; PubMed=17114649 [NCBI, ExPASy, EBI, Israel, Japan]
Munton R.P., Tweedie-Cullen R., Livingstone-Zatchej M., Weinandy F., Waidelich M., Longo D., Gehrig P., Potthast F., Rutishauser D., Gerrits B., Panse C., Schlapbach R., Mansuy I.M.;
"Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.";
Mol. Cell. Proteomics 6:283-293(2007).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AK078110; BAC37129.1; ALT_INIT; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
IPI IPI00621076; -.
UniGene Mm.277977
3D structure databases
HSSP P32851; 1JTH. [HSSP ENTRY / PDB]
ModBase Q8BVI5.
PTM databases
PhosphoSite Q8BVI5; -.
Organism-specific databases
MGI MGI:1923396; Stx16.
Gene expression databases
ArrayExpress Q8BVI5; -.
Bgee Q8BVI5; -.
CleanEx MM_STX16; -.
GermOnline ENSMUSG00000027522; Mus musculus.
Ontologies
GO
GO:0000139; Cellular component: Golgi membrane (inferred from electronic annotation from UniProtKB-SubCell).
GO:0016021; Cellular component: integral to membrane (inferred from electronic annotation from UniProtKB-KW).
GO:0005484; Molecular function: SNAP receptor activity (inferred from electronic annotation from InterPro).
GO:0006886; Biological process: intracellular protein transport (inferred from electronic annotation from InterPro).
GO:0016192; Biological process: vesicle-mediated transport (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
InterPro IPR006012; Syntaxin/epimorphin_CS.
IPR006011; Syntaxin_N.
IPR000727; T_SNARE.
Graphical view of domain structure.
Pfam PF05739; SNARE; 1.
PF00804; Syntaxin; 1.
Pfam graphical view of domain structure.
SMART SM00397; t_SNARE; 1.
SMART graphical view of domain structure.
PROSITE PS00914; SYNTAXIN; 1.
PS50192; T_SNARE; 1.
PROSITE graphical view of domain structure (profiles).
Genome annotation databases
Ensembl ENSMUSG00000027522; Mus musculus. [Contig view]
Phylogenomic databases
HOGENOM Q8BVI5; -.
HOVERGEN Q8BVI5; -.
Other
SOURCE Stx16; Mus musculus.
ProtoNet Q8BVI5.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Coiled coil; Golgi apparatus; Membrane; Phosphoprotein; Protein transport; Transmembrane; Transport.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   326  326     Syntaxin-16. PRO_0000210227
TOPO_DOM   1   302  302     Cytoplasmic (Potential). 
TRANSMEM   303   323  21     Anchor for type IV membrane protein (Potential). 
TOPO_DOM   324   326  3     Vesicular (Potential). 
DOMAIN   231   293  63     t-SNARE coiled-coil homology. 
MOD_RES   35    35        Phosphoserine. 
CONFLICT   1     1        M -> T (in Ref. 1; BAC37129). 
Sequence information
Length: 326 AA [This is the length of the unprocessed precursor] Molecular weight: 37052 Da [This is the MW of the unprocessed precursor] CRC64: 12992627BB4D385D [This is a checksum on the sequence]
        10         20         30         40         50         60 
MATRRLTDAF LLLRNNSIQT RQLLAEQVSS HTTSSPLHSR SIAADVDELA DDRMALVSGI 

        70         80         90        100        110        120 
SLDPEAAIGV TKRSPPKWVD GVDEIQYDVG RIKQKMKELA SLHDKHLNRP TLDDSSEEEH 

       130        140        150        160        170        180 
AIEITTQEVT QLFHRCQRAV QALPSRARRA CSEQEERLLR NVVASLAQAL QELSTSFRHA 

       190        200        210        220        230        240 
QSDYLKRMKN REERSQHFFD TPVPLMDDGD DATLYGQGFT DDQLVLVEQN TLMVEERERE 

       250        260        270        280        290        300 
IRQIVQSISD LNEIFRDLGA MIVEQGTVLD RIDYNVEQSC VKTEDGLKQL HKAEQYQKKN 

       310        320 
RKMLVIVILV AVIIVLLVAL VAVKSR 

Q8BVI5 in FASTA format

View entry in raw text format (no links)
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