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UniProtKB/Swiss-Prot entry Q7TN40


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name MRGRE_RAT
Primary accession number Q7TN40
Secondary accession numbers None
Integrated into Swiss-Prot on August 31, 2004
Sequence was last modified on October 1, 2003 (Sequence version 1)
Annotations were last modified on    June 16, 2009 (Entry version 39)
Name and origin of the protein
Protein name Mas-related G-protein coupled receptor member E
Synonyms None
Gene name
Name: Mrgpre
Synonyms: Mrge
From
Rattus norvegicus (Rat) [TaxID: 10116] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=Sprague-Dawley;
DOI=10.1073/pnas.1732949100; PubMed=12909716 [NCBI, ExPASy, EBI, Israel, Japan]
Zylka M.J., Dong X., Southwell A.L., Anderson D.J.;
"Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family.";
Proc. Natl. Acad. Sci. U.S.A. 100:10043-10048(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AF518247; AAQ08319.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
IPI IPI00454481; -.
RefSeq NP_001002288.1; -.
UniGene Rn.189891
3D structure databases
ModBase Q7TN40.
Protein family/group databases
GPCRDB Q7TN40; MRGRE_RAT.
Organism-specific databases
RGD 738045; Mrgpre.
Ontologies
GO
GO:0016021; Cellular component: integral to membrane (inferred from electronic annotation from UniProtKB-KW).
GO:0005886; Cellular component: plasma membrane (inferred from electronic annotation from UniProtKB-SubCell).
GO:0004930; Molecular function: G-protein coupled receptor activity (traceable author statement from RGD).
GO:0007186; Biological process: G-protein coupled receptor protein signaling pathway (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR000276; 7TM_GPCR_Rhodpsn.
IPR017452; GPCR_Rhodpsn_supfam.
Graphical view of domain structure.
Pfam PF00001; 7tm_1; 1.
Pfam graphical view of domain structure.
PRINTS PR00237; GPCRRHODOPSN.
PROSITE PS00237; G_PROTEIN_RECEP_F1_1; FALSE_NEG.
PS50262; G_PROTEIN_RECEP_F1_2; 1.
PROSITE graphical view of domain structure (profiles).
Genome annotation databases
Ensembl ENSRNOG00000020735; Rattus norvegicus. [Contig view]
GeneID 404660; -.
KEGG rno:404660; -.
Phylogenomic databases
HOVERGEN Q7TN40; -.
OMA Q7TN40; DVACADL.
Other
NextBio 692778; -.
GPCRDB-Snakes Q7TN40.
ProtoNet Q7TN40.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Cell membrane; G-protein coupled receptor; Glycoprotein; Membrane; Receptor; Transducer; Transmembrane.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   309  309     Mas-related G-protein coupled receptor member E. PRO_0000069763
TOPO_DOM   1    21  21     Extracellular (Potential). 
TRANSMEM   22    42  21     1 (Potential). 
TOPO_DOM   43    59  17     Cytoplasmic (Potential). 
TRANSMEM   60    80  21     2 (Potential). 
TOPO_DOM   81    91  11     Extracellular (Potential). 
TRANSMEM   92   112  21     3 (Potential). 
TOPO_DOM   113   132  20     Cytoplasmic (Potential). 
TRANSMEM   133   153  21     4 (Potential). 
TOPO_DOM   154   168  15     Extracellular (Potential). 
TRANSMEM   169   189  21     5 (Potential). 
TOPO_DOM   190   212  23     Cytoplasmic (Potential). 
TRANSMEM   213   233  21     6 (Potential). 
TOPO_DOM   234   247  14     Extracellular (Potential). 
TRANSMEM   248   268  21     7 (Potential). 
TOPO_DOM   269   309  41     Cytoplasmic (Potential). 
CARBOHYD   19    19        N-linked (GlcNAc...) (Potential). 
CARBOHYD   236   236        N-linked (GlcNAc...) (Potential). 
Sequence information
Length: 309 AA [This is the length of the unprocessed precursor] Molecular weight: 34511 Da [This is the MW of the unprocessed precursor] CRC64: 20F0424940FB9781 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSLRVHTHSP STQGDMAFNL TILSLTELLS LGGLLGNGVA LWLLNQNVYR NPFSIYLLDV 

        70         80         90        100        110        120 
ACADLIFLCC HMVAIIPELL QDQLNFPEFV HISLIMLRFF CYIVGLSLLV AISTEQCLAT 

       130        140        150        160        170        180 
LFPSGYLCRR PRYLTTCVCA FIWVLCLLLD LLLSGACTQF FGAPSYHLCG MLWLVVAVLL 

       190        200        210        220        230        240 
AALCCTMCVT SLLLLLRVER GPERHQPRGF PTLVLLVILL FLFCGLPFGI FWLSKNLSWH 

       250        260        270        280        290        300 
TPLYFYHFSF FMASVHSAAK PAIYFFLGST PGQRFQEPLR LVLQRALGDE AELGAVREAS 


QGGLVDMTV 

Q7TN40 in FASTA format

View entry in raw text format (no links)
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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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NPSA logo NPSA Sequence analysis tools

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