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UniProtKB/Swiss-Prot entry Q759G5

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name GPD_ASHGO
Primary accession number Q759G5
Secondary accession numbers None
Integrated into Swiss-Prot on January 10, 2006
Sequence was last modified on July 5, 2004 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 37)
Name and origin of the protein
Protein name Glycerol-3-phosphate dehydrogenase [NAD+]
Synonym EC 1.1.1.8
Gene name
Name: GPD
OrderedLocusNames: ADR311C
From
Ashbya gossypii (Yeast) (Eremothecium gossypii) [TaxID: 33169] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Eremothecium.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 10895 / NRRL Y-1056 / CBS 109.51;
DOI=10.1126/science.1095781; PubMed=15001715 [NCBI, ExPASy, EBI, Israel, Japan]
Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S., Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A., Gaffney T.D., Philippsen P.;
"The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces cerevisiae genome.";
Science 304:304-307(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE016817; AAS52231.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_984407.1; -.
3D structure databases
HSSP P90551; 1JDJ. [HSSP ENTRY / PDB]
ModBase Q759G5.
Organism-specific databases
AGD ADR311C; -.
Ontologies
GO
GO:0009331; Cellular component: glycerol-3-phosphate dehydrogenase complex (inferred from electronic annotation from InterPro).
GO:0004367; Molecular function: glycerol-3-phosphate dehydrogenase (NAD+) activity (inferred from electronic annotation from InterPro).
GO:0051287; Molecular function: NAD binding (inferred from electronic annotation from InterPro).
GO:0005975; Biological process: carbohydrate metabolic process (inferred from electronic annotation from InterPro).
GO:0046168; Biological process: glycerol-3-phosphate catabolic process (inferred from electronic annotation from InterPro).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR013328; DHase_multihelical.
IPR016040; NAD(P)-bd.
IPR017751; NAD-dep_Gly3P_DH_euk.
IPR006168; NAD-dep_Gly3P_DHase.
IPR011128; NAD-dep_Gly3P_DHase_N.
IPR006109; NAD_Gly3P_DHase_C.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
G3DSA:1.10.1040.10; Opine_DH; 1.
PANTHER PTHR11728; NAD_Gly3P_DH; 1.
Pfam PF07479; NAD_Gly3P_dh_C; 1.
PF01210; NAD_Gly3P_dh_N; 1.
Pfam graphical view of domain structure.
PRINTS PR00077; GPDHDRGNASE.
ProDom PD001278; NAD_Gly3P_C; 1.
[Domain structure / List of seq. sharing at least 1 domain]
PROSITE PS00957; NAD_G3PDH; 1.
ProtoNet Q759G5.
Genome annotation databases
GeneID 4620680; -.
KEGG ago:AGOS_ADR311C; -.
NMPDR fig|33169.1.peg.2052; -.
Phylogenomic databases
HOGENOM Q759G5; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   424  424     Glycerol-3-phosphate dehydrogenase [NAD+]. PRO_0000138085
NP_BIND   79    84  6     NAD (By similarity). 
REGION   348   349  2     Substrate binding (By similarity). 
ACT_SITE   283   283        Proton acceptor (By similarity). 
BINDING   167   167        NAD (By similarity). 
BINDING   190   190        NAD; via amide nitrogen (By similarity). 
BINDING   190   190        Substrate (By similarity). 
BINDING   223   223        NAD; via amide nitrogen (By similarity). 
BINDING   348   348        NAD (By similarity). 
BINDING   377   377        NAD (By similarity). 
Sequence information
Length: 424 AA [This is the length of the unprocessed precursor] Molecular weight: 46646 Da [This is the MW of the unprocessed precursor] CRC64: 014C3D1A7F251630 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MVNTTALIRS PTFVAQFRVL KQVNRGLFSQ TSYARTHART SYTHTMAGTD RLQQTSQILS 

        70         80         90        100        110        120 
RSTSSEIRLE RPFKVTVIGS GNWGTTIAKV VAENTQEYPQ LFERRVDMWV FEEQIEGRKL 

       130        140        150        160        170        180 
TEIINEQHEN VKYLPGITLP ENLVANPSVA AAAADADVLV FNIPHQFLGR IVEQLKGHVK 

       190        200        210        220        230        240 
PGARAISCLK GFSVGKDGVQ LLSTYIEEHL HIPCGALSGA NLAPEVAKGN WSETTVAYTL 

       250        260        270        280        290        300 
PQDFRGTGKD VDHAVLKKLF HRPYFHVNVV DDVAGISVAG ALKNVVALAC GFVLGLGWGN 

       310        320        330        340        350        360 
NAAAAVQRVG LSEMIKFARM FFPESKVETF YQESAGVADL ITTCAGGRNV RIGRAMAETG 

       370        380        390        400        410        420 
KSAQELEKEL LNGQSSQGIY TTQEVHEWLQ QCGKKDEFPL FEAVYKIVYE GVPMSKLPDM 


LEDA
Q759G5 in FASTA format

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