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UniProtKB/Swiss-Prot entry Q730K1


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name AROE_BACC1
Primary accession number Q730K1
Secondary accession numbers None
Integrated into Swiss-Prot on January 15, 2008
Sequence was last modified on July 5, 2004 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 38)
Name and origin of the protein
Protein name Shikimate dehydrogenase
Synonym EC 1.1.1.25
Gene name
Name: aroE
OrderedLocusNames: BCE_4415
From
Bacillus cereus (strain ATCC 10987) [TaxID: 222523] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus; Bacillus cereus group.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1093/nar/gkh258; PubMed=14960714 [NCBI, ExPASy, EBI, Israel, Japan]
Rasko D.A., Ravel J., Oekstad O.A., Helgason E., Cer R.Z., Jiang L., Shores K.A., Fouts D.E., Tourasse N.J., Angiuoli S.V., Kolonay J.F., Nelson W.C., Kolstoe A.-B., Fraser C.M., Read T.D.;
"The genome sequence of Bacillus cereus ATCC 10987 reveals metabolic adaptations and a large plasmid related to Bacillus anthracis pXO1.";
Nucleic Acids Res. 32:977-988(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE017194; AAS43316.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_980708.1; -.
3D structure databases
HSSP P15770; 1NYT. [HSSP ENTRY / PDB]
ModBase Q730K1.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from InterPro).
GO:0050661; Molecular function: NADP binding (inferred from electronic annotation from InterPro).
GO:0004764; Molecular function: shikimate 5-dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0009073; Biological process: aromatic amino acid family biosynthetic process (inferred from electronic annotation from HAMAP).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
HAMAP MF_00222; -; 1.
PBIL [Tree]
InterPro IPR016040; NAD(P)-bd.
IPR011342; Quinate/shikimate_5-DHase.
IPR013708; Shikimate_DHase-bd_N.
IPR006151; Shikm_DHase/Glu-tRNA_Rdtase.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF01488; Shikimate_DH; 1.
PF08501; Shikimate_dh_N; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00507; aroE; 1.
ProtoNet Q730K1.
Genome annotation databases
GeneID 2748408; -.
GenomeReviews AE017194_GR; BCE_4415.
KEGG bca:BCE_4415; -.
NMPDR fig|222523.1.peg.4380; -.
TIGR BCE_4415; -.
Phylogenomic databases
HOGENOM Q730K1; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Aromatic amino acid biosynthesis; Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   277  277     Shikimate dehydrogenase. PRO_1000021259
NP_BIND   127   131  5     NADP (By similarity). 
ACT_SITE   66    66        Proton acceptor (Potential). 
Sequence information
Length: 277 AA [This is the length of the unprocessed precursor] Molecular weight: 30294 Da [This is the MW of the unprocessed precursor] CRC64: 3492E61278FE50FC [This is a checksum on the sequence]
        10         20         30         40         50         60 
MKQLYGVIGN PIGHSLSPVM HNDAFEHLNM DAHYHAFLVK EEVLGEAVRG LKALGISGFN 

        70         80         90        100        110        120 
VTTPHKVAIM DYLDEIDPLA KQIGAVNTVV HKDGKLIGYN TDGIGFVRAL QSISSKPLQE 

       130        140        150        160        170        180 
KRILLLGAGG ASRAIYFSLA DVGVKEIDVA NRTVDKAKEL ITACKATVHS VALSLEKATE 

       190        200        210        220        230        240 
EQGNYDIIIQ TTTIGMHPRV EHTPLQISSL NKGTIVSDII YNPFETKILC EAKEQGAMIQ 

       250        260        270 
NGIDMFVYQG ALAFEMWTGR TPNIERMKQL VIRKLGG 

Q730K1 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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