NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1007/s00239-003-2464-z; PubMed=14562961 [NCBI, ExPASy, EBI, Israel, Japan]
Goulielmos G.N., Loukas M., Bondinas G., Zouros E.;
"Exploring the evolutionary history of the alcohol dehydrogenase gene (Adh) duplication in species of the family tephritidae.";
J. Mol. Evol. 57:170-180(2003).

Comments

CATALYTIC ACTIVITY: An alcohol + NAD⁺ = an aldehyde or ketone + NADH.
SUBUNIT: Homodimer (By similarity).
SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AJ539546; CAD62458.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

3D structure databases

HSSP

P10807; 1B16. [HSSP ENTRY / PDB]

ModBase

Q70UN9.

Ontologies

GO:0004022;	Molecular function: alcohol dehydrogenase activity (inferred from electronic annotation from InterPro).
GO:0005488;	Molecular function: binding (inferred from electronic annotation from InterPro).
GO:0055114;	Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.

Family and domain databases

InterPro

IPR002426; Ceratitis_AlcDHase.
IPR002198; DHase_sc/Rdtase_SDR.
IPR002424; Insect_AlcDHase_fam.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.50.720; NAD(P)-bd; 1.

PANTHER

PTHR19410; ADH_short_C2; 1.

Pfam

PF00106; adh_short; 1.
Pfam graphical view of domain structure.

PRINTS

PR01169; CERATITISADH.
PR01167; INSADHFAMILY.
PR00080; SDRFAMILY.

PROSITE

PS00061; ADH_SHORT; 1.

ProtoNet

Q70UN9.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

NAD; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 257`	`257`	`Alcohol dehydrogenase 1.`	`PRO_0000277838`
`NP_BIND`	`9 33`	`25`	`NAD (By similarity).`
`ACT_SITE`	`150 150`		`Proton acceptor (By similarity).`
`BINDING`	`137 137`		`Substrate (By similarity).`

Sequence information

Length: 257 AA [This is the length of the unprocessed precursor]

Molecular weight: 28052 Da [This is the MW of the unprocessed precursor]

CRC64: 62DE72372695D348 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MSVAGKNVVF VGGLGFIGYE ACKTLITRDL ASLFVFDILD KPEAVKALEE INPKTKVYYT 

        70         80         90        100        110        120 
KFDITSKDNI KQSLADVIAK VQYIDVLVNG AGILNDPNVE WTMNINLIGL INTTLEAIPL 

       130        140        150        160        170        180 
MDKNKKGRGG VIVNIASVLG LEPGPPAAIY CASKFGVMGF SRSLGDPHYY EHTGIAVVTF 

       190        200        210        220        230        240 
CPGLTDTPLK NNVATKYTFD YSKEIGEKLN HSKTQKPEVC GAHLAQVIEL RDNGAIYISN 

       250 
QGTLTKVKPS VYWEPTY

Q70UN9 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools