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[1]
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NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Brain;
Dang Y.,
Yu L.,
Wu J.,
Pei Y.;
"Cloning and characterization of rat lc3 orthologs.";
Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases.
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[2]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Ovary;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
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[3]
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PROTEIN SEQUENCE OF 31-37, AND MASS SPECTROMETRY.
STRAIN=Sprague-Dawley;
TISSUE=Brain;
Lubec G.,
Kang S.U.;
Submitted (JUL-2007) to UniProtKB.
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- FUNCTION: Probably involved in formation of autophagosomal vacuoles (autophagosomes) (By similarity).
- SUBUNIT: 3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins (By similarity).
- SUBCELLULAR LOCATION: Cytoplasm. Intracytoplasmic membrane; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor (By similarity). Note=LC3-II binds to the autophagic membranes (By similarity).
- PTM: The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II (By similarity).
- SIMILARITY: Belongs to the MAP1 LC3 family.
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Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms.
Distributed under the Creative Commons Attribution-NoDerivs License.
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| Length: 121 AA [This is the length of the unprocessed precursor] |
Molecular weight: 14272 Da [This is the MW of the unprocessed precursor] |
CRC64: 48C1FBE8F7892AF3 [This is a checksum on the sequence] |
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10 20 30 40 50 60
MPSDRPFKQR RSFADRCKEV QQIRDQHPSK IPVIIERYKG EKQLPVLDKT KFLVPDHVNM
70 80 90 100 110 120
SELVKIIRRR LQLNPTQAFF LLVNQHSMVS VSTPIADIYE QEKDEDGFLY MVYASQETFG
F
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Q6XVN8 in FASTA format |
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