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UniProtKB/Swiss-Prot entry Q6JZS3

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name CP1A1_ORYLA
Primary accession number Q6JZS3
Secondary accession numbers None
Integrated into Swiss-Prot on October 11, 2005
Sequence was last modified on July 5, 2004 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 34)
Name and origin of the protein
Protein name Cytochrome P450 1A1
Synonyms EC 1.14.14.1
CYPIA1
Gene name
Name: cyp1a1
Synonyms: cyp1a
From
Oryzias latipes (Medaka fish) (Japanese ricefish) [TaxID: 8090] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei; Acanthomorpha; Acanthopterygii; Percomorpha; Atherinomorpha; Beloniformes; Adrianichthyidae; Oryziinae; Oryzias.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1016/j.marenvres.2004.03.006; PubMed=15178024 [NCBI, ExPASy, EBI, Israel, Japan]
Kim I.-C., Kim Y.J., Yoon Y.-D., Kawamura S., Lee Y.-S., Lee J.-S.;
"Cloning of cytochrome P450 1A (CYP1A) genes from the hermaphrodite fish Rivulus marmoratus and the Japanese medaka Oryzias latipes.";
Mar. Environ. Res. 58:125-129(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AY233000; AAP68769.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
3D structure databases
ModBase Q6JZS3.
Ontologies
GO
GO:0005789; Cellular component: endoplasmic reticulum membrane (inferred from electronic annotation from UniProtKB-SubCell).
GO:0005792; Cellular component: microsome (inferred from electronic annotation from UniProtKB-KW).
GO:0009055; Molecular function: electron carrier activity (inferred from electronic annotation from InterPro).
GO:0020037; Molecular function: heme binding (inferred from electronic annotation from InterPro).
GO:0005506; Molecular function: iron ion binding (inferred from electronic annotation from InterPro).
GO:0050381; Molecular function: unspecific monooxygenase activity (inferred from electronic annotation from EC).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR001128; Cyt_P450.
IPR002401; Cyt_P450_E_grp-I.
IPR008066; Cyt_P450_E_grp-I_CYP1.
Graphical view of domain structure.
Gene3D G3DSA:1.10.630.10; Cyt_P450; 1.
PANTHER PTHR19383; Cyt_P450; 1.
PTHR19383:SF63; Cyt_P450_E_grp-I_CYP1; 1.
Pfam PF00067; p450; 1.
Pfam graphical view of domain structure.
PRINTS PR00463; EP450I.
PR01683; EP450ICYP1A.
PR00385; P450.
PROSITE PS00086; CYTOCHROME_P450; 1.
ProtoNet Q6JZS3.
Genome annotation databases
Ensembl ENSORLG00000014421; Oryzias latipes. [Contig view]
Phylogenomic databases
HOVERGEN Q6JZS3; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Endoplasmic reticulum; Heme; Iron; Membrane; Metal-binding; Microsome; Monooxygenase; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   521  521     Cytochrome P450 1A1. PRO_0000051644
METAL   463   463        Iron (heme axial ligand) (By similarity). 
Sequence information
Length: 521 AA [This is the length of the unprocessed precursor] Molecular weight: 58887 Da [This is the MW of the unprocessed precursor] CRC64: E36092B9E9957AF3 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MALMVLPFIG PLSVLEGLIA LTTVCVVYLL LKHFNKEIPG GLRQLPGPTP LPIIGNLLKL 

        70         80         90        100        110        120 
GSKPYLSLTE MSKRFGDVFQ IQIGMRPVVV LSGNETVRQA LIKQGDDFSG RPDLYSFQFI 

       130        140        150        160        170        180 
NDGKSLAFST DQAGVWRARR KLAYSALRSF SSLEGSNAEY SCMLEEHICK ETEHLVKEIE 

       190        200        210        220        230        240 
KVMKTEGKFD PYRYIVVSVA NVICGMCFGR RYDHHDQELV GLVNLSEDFV QVTGSGNPAD 

       250        260        270        280        290        300 
FIPALRYLPS KAMKKFVEIN NRFQSFVQKI VNEHSATYDK DNIRDITDSL IDHCEDRKLD 

       310        320        330        340        350        360 
ENSNIQMSDE KVVGIVNDLF GAGFDTISTA LSWAVGYLVA YPDIEKGLFE EIKENIGLNR 

       370        380        390        400        410        420 
NPTISDRSNL PLTDAFILEI FRHSSFLPFT IPHCTTRDTS LNGYYIPKDT CVFINQWQIN 

       430        440        450        460        470        480 
HDPKLWQDPS SFNPDRFLSE DGSEVNRLDG EKVMVFGLGK RRCIGEVIAR NEVFLFLAIM 

       490        500        510        520 
IQKLCFEEMP GEPLDMTPEY GLTMKHKRCN VRASLRLKDG C
Q6JZS3 in FASTA format

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