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UniProtKB/Swiss-Prot entry Q6EBV9

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ATG9B_MOUSE
Primary accession number Q6EBV9
Secondary accession number Q674R6
Integrated into Swiss-Prot on January 15, 2008
Sequence was last modified on August 16, 2004 (Sequence version 1)
Annotations were last modified on    June 16, 2009 (Entry version 35)
Name and origin of the protein
Protein name Autophagy-related protein 9B
Synonyms APG9-like 2
Nitric oxide synthase 3-overlapping antisense gene protein
Gene name
Name: Atg9b
Synonyms: Apg9l2, Nos3as
From
Mus musculus (Mouse) [TaxID: 10090] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus.
Protein existence 2: Evidence at transcript level;
References
[1]
 NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
STRAIN=129S6/SvEvTac, and CD-1;
TISSUE=Placenta;
DOI=10.1074/jbc.M400271200; PubMed=15234981 [NCBI, ExPASy, EBI, Israel, Japan]
Robb G.B., Carson A.R., Tai S.C., Fish J.E., Singh S., Yamada T., Scherer S.W., Nakabayashi K., Marsden P.A.;
"Post-transcriptional regulation of endothelial nitric-oxide synthase by an overlapping antisense mRNA transcript.";
J. Biol. Chem. 279:37982-37996(2004).
[2]
 FUNCTION, SUBCELLULAR LOCATION, AND TISSUE SPECIFICITY.
DOI=10.1074/jbc.M413957200; PubMed=15755735 [NCBI, ExPASy, EBI, Israel, Japan]
Yamada T., Carson A.R., Caniggia I., Umebayashi K., Yoshimori T., Nakabayashi K., Scherer S.W.;
"Endothelial nitric-oxide synthase antisense (NOS3AS) gene encodes an autophagy-related protein (APG9-like2) highly expressed in trophoblast.";
J. Biol. Chem. 280:18283-18290(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AY495541; AAS72555.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY515312; AAS87213.1; ALT_INIT; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY515313; AAS87214.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BK004021; DAA05202.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
IPI IPI00268141; -.
RefSeq NP_001002897.2; -.
UniGene Mm.332252
3D structure databases
ModBase Q6EBV9.
Organism-specific databases
MGI MGI:2685420; Atg9b.
Gene expression databases
ArrayExpress Q6EBV9; -.
Bgee Q6EBV9; -.
Ontologies
GO
GO:0000421; Cellular component: autophagic vacuole membrane (inferred from electronic annotation from UniProtKB-SubCell).
GO:0031410; Cellular component: cytoplasmic vesicle (inferred from electronic annotation from UniProtKB-SubCell).
GO:0016021; Cellular component: integral to membrane (inferred from electronic annotation from UniProtKB-KW).
GO:0006914; Biological process: autophagy (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR007241; Autophagy-rel_prot_9.
Graphical view of domain structure.
PANTHER PTHR13038; APG9; 1.
Pfam PF04109; APG9; 1.
Pfam graphical view of domain structure.
Genome annotation databases
Ensembl ENSMUSG00000038295; Mus musculus. [Contig view]
GeneID 213948; -.
KEGG mmu:213948; -.
Phylogenomic databases
HOGENOM Q6EBV9; -.
HOVERGEN Q6EBV9; -.
Other
NextBio 374136; -.
SOURCE Atg9b; Mus musculus.
ProtoNet Q6EBV9.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Autophagy; Cytoplasmic vesicle; Membrane; Transmembrane.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   922  922     Autophagy-related protein 9B. PRO_0000314868
TOPO_DOM   1   206  206     Cytoplasmic (By similarity). 
TRANSMEM   207   227  21     Potential. 
TOPO_DOM   228   275  48     Lumenal (By similarity). 
TRANSMEM   276   296  21     Potential. 
TOPO_DOM   297   437  141     Cytoplasmic (By similarity). 
TRANSMEM   438   458  21     Potential. 
TOPO_DOM   459   523  65     Lumenal (By similarity). 
TRANSMEM   524   544  21     Potential. 
TOPO_DOM   545   550  6     Cytoplasmic (By similarity). 
TRANSMEM   551   571  21     Potential. 
TOPO_DOM   572   624  53     Lumenal (By similarity). 
TRANSMEM   625   645  21     Potential. 
TOPO_DOM   646   922  277     Cytoplasmic (By similarity). 
COMPBIAS   86   146  61     Pro-rich. 
Sequence information
Length: 922 AA [This is the length of the unprocessed precursor] Molecular weight: 101953 Da [This is the MW of the unprocessed precursor] CRC64: 450179EDD6C8496A [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MVRRTGWGGS RRQRGRWGDL GPSSVPLLHM ALPLPASPCR GTGGRRISVF SLSPAPRTRS 

        70         80         90        100        110        120 
CSSSVFPPAS GSPCLVIQEA GASQTPHNVL PTPTTPSTQA HPTMIHTSAS PSWGSHSTPP 

       130        140        150        160        170        180 
LASATPPPSC PRPQDHPGLR MGPLIPEQDY ERLEDCDPEG SQDSPIHGED HQPLLHVPEG 

       190        200        210        220        230        240 
LRGSWHHIQN LDSFFTKIYS YHQRNGFACI LLEDVFQLGQ FIFIVTFTTF LLRCVDYNVL 

       250        260        270        280        290        300 
FNNQPKNHTR RGPLHSKVTL SDAILPSAQC AEKIHDSPLL VFLLVLAAGF WLFQLLRSVC 

       310        320        330        340        350        360 
NLFSYWDIQV FYREALHIPP EELSSVPWAE VQSRLLELQR SGGLCVQPRP LTELDVHHRI 

       370        380        390        400        410        420 
LRYTNYQVAL ANKGLLPARC PLPWGSSAAF LSRGLALNVD LLLFRGPFSL FRGGWELPEA 

       430        440        450        460        470        480 
YKRSDLRGVL ANRWRRTVLL LAAVNLALSP LVLAWQVLHA FYSHVELLRR EPGAFGARRW 

       490        500        510        520        530        540 
SRLARLQLRH FNELPHELRA RLGRAYRPAA AFLRAAEPPA PLRALLARQL VFFSGALFAA 

       550        560        570        580        590        600 
LLVLTIYDED VLAVEHVLTT MTALGVTATV ARSFIPEEQC QGRSSQLLLQ AALAHMHYLP 

       610        620        630        640        650        660 
EEPGATGARA SSYWQMAQLL QYRAVSLLEE LLSPLLTPLF LLFWFRPRAL EIIDFFHHFT 

       670        680        690        700        710        720 
VDVAGVGDIC SFALMDVKRH GHPQWLSEGQ TEASLSQRAE DGKTELSLMR FSLAHPQWQP 

       730        740        750        760        770        780 
PGHSSKFLGH LRGRVQQDAA AWGAPSTRSP PTPGVLSDCT SPLPEAFLAN LLVNPRPPQR 

       790        800        810        820        830        840 
DLSPTAPCPA AATASLLASI SRMVQDPSCV SPGGTGGQKL TQLPELVSAE MSLHAIYLHQ 

       850        860        870        880        890        900 
LHQQQQQELW GEASASSPSR PWSSPSQPGS PDEEKPSWSS DGSSPASSPR QQWGTQRAQN 

       910        920 
LFPKGFQENT DTQKEPLTGP LH
Q6EBV9 in FASTA format

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