NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=C57BL/6;
TISSUE=Brain;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).

Comments

FUNCTION: Plays a role in autophagy (By similarity).
SUBCELLULAR LOCATION: Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein (By similarity).
MISCELLANEOUS: Isoform displayed in this entry matches to human isoform 3.
SIMILARITY: Belongs to the ATG9 family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

BC079884; AAH79884.1; -; mRNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

UniGene

Mm.358931

3D structure databases

ModBase

Q68FE2.

Organism-specific databases

MGI

MGI:2138446; Atg9a.

GeneLynx

Atg9a; Mus musculus.

Gene expression databases

CleanEx

MM_ATG9A; -.

GermOnline

ENSMUSG00000033124; Mus musculus.

Ontologies

GO:0005776;	Cellular component: autophagic vacuole (inferred from direct assay from MGI).
QuickGo view.

Family and domain databases

InterPro

IPR007241; Autophagy_prot_99.
Graphical view of domain structure.

PANTHER

PTHR13038; APG9; 1.

Pfam

PF04109; APG9; 1.
Pfam graphical view of domain structure.

BLOCKS

Q68FE2.

Genome annotation databases

Ensembl

ENSMUSG00000033124; Mus musculus. [Contig view]

Phylogenomic databases

HOVERGEN

Q68FE2; -.

Other

Atg9a; Mus musculus.

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Autophagy; Cytoplasmic vesicle; Membrane; Protein transport; Transmembrane; Transport.

Features

Feature table viewer

Feature aligner

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 551`	`551`	`Autophagy-related protein 9A.`	`PRO_0000119821`
`TRANSMEM`	`73 93`	`21`	`Potential.`
`TRANSMEM`	`132 152`	`21`	`Potential.`
`TRANSMEM`	`290 310`	`21`	`Potential.`
`TRANSMEM`	`372 392`	`21`	`Potential.`
`TRANSMEM`	`401 421`	`21`	`Potential.`

Sequence information

Length: 551 AA [This is the length of the unprocessed precursor]

Molecular weight: 63138 Da [This is the MW of the unprocessed precursor]

CRC64: BDCDBA33E0D10C26 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MAQFDTEYQR LEASYSDSPP GEEDLLVHVA EGSKSPWHHI ENLDLFFSRV YNLHQKNGFT 

        70         80         90        100        110        120 
CMLIGEMFEL MQFLFVVAFT TFLVSCVDYD ILFANKMVNH SLHPTEPVKV TLPDAFLPAQ 

       130        140        150        160        170        180 
VCSARIQENG SLITILVIAG VFWIHRLIKF IYNICCYWEI HSFYLHALRI PMSALPYCTW 

       190        200        210        220        230        240 
QEVQARIVQT QKEHQICIHK RELTELDIYH RILRFQNYMV ALVNKSLLPL RFRLPGLGEV 

       250        260        270        280        290        300 
VFFTRGLKYN FELILFWGPG SLFLNEWSLK AEYKRGGQRL ELAQRLSNRI LWIGIANFLL 

       310        320        330        340        350        360 
CPLILIWQIL YAFFSYAEVL KREPGALGAR CWSLYGRCYL RHFNELEHEL QSRLNRGYKP 

       370        380        390        400        410        420 
ASKYMNCFLS PLLTLLAKNG AFFAGSILAV LIALTIYDED VLAVEHVLTT VTLLGVTVTV 

       430        440        450        460        470        480 
CRSFIPDQHM VFCPEQLLRV ILAHIHYMPD HWQGVHLGGV AESHRHTPHS HLLPPPSGPG 

       490        500        510        520        530        540 
DHRLLPQLYG RGRGCGRHLL LCSDGRSPAW PSSVAVWRAD RGLSVPASRG REDRVVAHAL 

       550 
CHHQSRLAAP S

Q68FE2 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools