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UniProtKB/TrEMBL entry Q549A5


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name Q549A5_MOUSE
Primary accession number Q549A5
Secondary accession numbers None
Integrated into TrEMBL on May 24, 2005
Sequence was last modified on May 24, 2005 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 20)
Name and origin of the protein
Protein name Clusterin (Sulfated glycoprotein-2 isoform 1) [Precursor]
Synonyms None
Gene name
Name: Clu
From
Mus musculus (Mouse) [TaxID: 10090] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE.
STRAIN=SvJ/129;
PubMed=11067863 [NCBI, ExPASy, EBI, Israel, Japan]
McLaughlin L., Zhu G., Mistry M., Ley-Ebert C., Stuart W.D., Florio C.J., Groen P.A., Witt S.A., Kimball T.R., Witte D.P., Harmony J.A., Aronow B.J.;
"Apolipoprotein J/clusterin limits the severity of murine autoimmune myocarditis.";
J. Clin. Invest. 106:1105-1113(2000).
[2]
NUCLEOTIDE SEQUENCE.
STRAIN=SvJ/129;
Zhu G., Ley-Ebert C., Barrie A.M. III, Witte D.P., Rosenberg M., Harmony J.A.K., Aronow B.J.;
"Clusterin Gene Locus Structure and Function in Development, Homeostasis, and Tissue Injury.";
(In) Landes R.G. (eds.); CLUSTERIN IN NORMAL BRAIN FUNCTIONS AND DURING NEURODEGENERATION., pp.1-16, Springer-Verlag, Austin, TX (1999).
[3]
NUCLEOTIDE SEQUENCE.
STRAIN=SvJ/129;
Jordan-Starck T.C., Ley-Ebert C., Zhu G., Johnson J.A., Harmony J.A.K., Aronow B.J.;
Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases.
[4]
NUCLEOTIDE SEQUENCE.
STRAIN=Balb/c;
TISSUE=Uterus;
You K.H., Jeon J.H.;
"Identification of Truncated SGP-2 Lacking a Signal Peptide for Secretion.";
Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AF182509; AAF06365.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AF248057; AAF67184.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
UniGene Mm.200608
3D structure databases
ModBase Q549A5.
Organism-specific databases
MGI MGI:88423; Clu.
Gene expression databases
ArrayExpress Q549A5; -.
Ontologies
GO
GO:0008219; Biological process: cell death (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
InterPro IPR016016; Clusterin.
IPR000753; Clusterin-like.
IPR016015; Clusterin_C.
IPR016014; Clusterin_N.
Graphical view of domain structure.
PANTHER PTHR10970:SF1; Clusterin; 1.
Pfam PF01093; Clusterin; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF002368; Clusterin; 1.
SMART SM00035; CLa; 1.
SM00030; CLb; 1.
SMART graphical view of domain structure.
PROSITE PS00492; CLUSTERIN_1; 1.
PS00493; CLUSTERIN_2; 1.
Genome annotation databases
Ensembl ENSMUSG00000022037; Mus musculus. [Contig view]
NMPDR fig|10090.3.peg.29296; -.
Phylogenomic databases
HOVERGEN Q549A5; -.
Other
SOURCE Clu; Mus musculus.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Signal.
Features
SEVIEWER logo Feature table viewer
KeyFrom  To Length Description FTId
SIGNAL   1    17  17     Potential. 
CHAIN   18   448  431     Potential. PRO_5000057055
Sequence information
Length: 448 AA [This is the length of the unprocessed precursor] Molecular weight: 51656 Da [This is the MW of the unprocessed precursor] CRC64: A860600A6F8D47F6 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MKILLLCVAL LLIWDNGMVL GEQEVSDNEL QELSTQGSRY INKEIQNAVQ GVKHIKTLIE 

        70         80         90        100        110        120 
KTNAERKSLL NSLEEAKKKK EDALEDTRDS EMKLKAFPEV CNETMMALWE ECKPCLKHTC 

       130        140        150        160        170        180 
MKFYARVCRS GSGLVGQQLE EFLNQSSPFY FWMNGDRIDS LLESDRQQSQ VLDAMQDSFA 

       190        200        210        220        230        240 
RASGIIDTLF QDRFFARELH DPHYFSPIGF PHKRPHFLYP KSRLVRSLMS PSHYGPPSFH 

       250        260        270        280        290        300 
NMFQPFFEMI HQAQQAMDVQ LHSPAFQFPD VDFLREGEDD RTVCKEIRRN STGCLKMKGQ 

       310        320        330        340        350        360 
CEKCQEILSV DCSTNNPAQA NLRQELNDSL QVAERLTEQY KELLQSFQSK MLNTSSLLEQ 

       370        380        390        400        410        420 
LNDQFNWVSQ LANLTQGEDK YYLRVSTVTT HSSDSEVPSR VTEVVVKLFD SDPITVVLPE 

       430        440 
EVSKDNPKFM DTVAEKALQE YRRKSRAE 

Q549A5 in FASTA format

View entry in original UniProtKB/TrEMBL format
View entry in raw text format (no links)
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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NPSA logo NPSA Sequence analysis tools

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