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UniProtKB/Swiss-Prot entry Q48LC8

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name MAO1_PSE14
Primary accession number Q48LC8
Secondary accession numbers None
Integrated into Swiss-Prot on December 6, 2005
Sequence was last modified on December 6, 2005 (Sequence version 2)
Annotations were last modified on    November 4, 2008 (Entry version 23)
Name and origin of the protein
Protein name NAD-dependent malic enzyme
Synonyms NAD-ME
EC 1.1.1.38
Gene name
Name: sfcA
OrderedLocusNames: PSPPH_1545
From
Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6) [TaxID: 264730] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1128/JB.187.18.6488-6498.2005; PubMed=16159782 [NCBI, ExPASy, EBI, Israel, Japan]
Joardar V., Lindeberg M., Jackson R.W., Selengut J., Dodson R., Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S., Gwinn Giglio M., Madupu R., Nelson W.C., Rosovitz M.J., Sullivan S.A., Crabtree J., Creasy T., Davidsen T.M., Haft D.H., Zafar N., Zhou L., Halpin R., Holley T., Khouri H.M., Feldblyum T.V., White O., Fraser C.M., Chatterjee A.K., Cartinhour S., Schneider D., Mansfield J.W., Collmer A., Buell R.;
"Whole-genome sequence analysis of Pseudomonas syringae pv. phaseolicola 1448A reveals divergence among pathovars in genes involved in virulence and transposition.";
J. Bacteriol. 187:6488-6498(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000058; AAZ37192.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_273797.1; -.
3D structure databases
ModBase Q48LC8.
Ontologies
GO
GO:0016619; Molecular function: malate dehydrogenase (oxaloacetate-decarboxylating) activity (inferred from electronic annotation from HAMAP).
GO:0046872; Molecular function: metal ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
HAMAP MF_01619; -; 1.
PBIL [Tree]
InterPro IPR015884; Malic_enzyme_CS.
IPR012301; Malic_N.
IPR012302; Malic_NAD_bd.
IPR001891; Malic_OxRdtase.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF00390; malic; 1.
PF03949; Malic_M; 1.
Pfam graphical view of domain structure.
PRINTS PR00072; MALOXRDTASE.
PROSITE PS00331; MALIC_ENZYMES; 1.
BLOCKS Q48LC8.
ProtoNet Q48LC8.
Genome annotation databases
GeneID 3559835; -.
GenomeReviews CP000058_GR; PSPPH_1545.
KEGG psp:PSPPH_1545; -.
NMPDR fig|264730.3.peg.1701; -.
Phylogenomic databases
HOGENOM Q48LC8; -.
Genome annotation databases
CMR Q48LC8; PSPPH_1545.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Metal-binding; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   563  563     NAD-dependent malic enzyme. PRO_0000160223
ACT_SITE   101   101        Proton donor (By similarity). 
ACT_SITE   172   172        Proton acceptor (By similarity). 
METAL   243   243        Divalent metal cation (By similarity). 
METAL   244   244        Divalent metal cation (By similarity). 
METAL   267   267        Divalent metal cation (By similarity). 
BINDING   154   154        NAD (By similarity). 
BINDING   267   267        NAD (By similarity). 
BINDING   416   416        NAD (By similarity). 
SITE   267   267  1     Important for activity (By similarity). 
Sequence information
Length: 563 AA [This is the length of the unprocessed precursor] Molecular weight: 62185 Da [This is the MW of the unprocessed precursor] CRC64: 078CC4BA1DC8F8BE [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MTKTSRPLYI SYAGPSLLEM PLLNKGSAFT PQERVEFNLI GLLPQNVETI EEQVTRVYSQ 

        70         80         90        100        110        120 
YKQCASDLDK HIYLRSIQDN NETLFFRLLD SHLDEMLPII YTPTVGQACQ EFSKIYRTHR 

       130        140        150        160        170        180 
GLFISYPERD RIDDILRSAT KDRIKIIVVT DSERILGLGD QGIGGMGIPI GKLSLYTACG 

       190        200        210        220        230        240 
GISPAYTLPI VLDVGTNNRE LLDDPMYMGW RHERVSGKEY EDFIALFIDA VQRRWPDVLL 

       250        260        270        280        290        300 
QFEDFAQSNA MPLLEKYRDE LCCFNDDIQG TASVAVGTLL AACKAKNETL GQQKVVFVGA 

       310        320        330        340        350        360 
GSAGCGIAEH IIAAMRIEGL SESEARKRIF MVDRFGLLTE GMDNLLDFQK RLAQKTADVS 

       370        380        390        400        410        420 
GWTAGTEAFP QLLDVVTNAG ATVLIGVSGQ RGLFTEQVIR ELHKHCAKPL VMPLSNPTSK 

       430        440        450        460        470        480 
VEATPEEILR WTDGNALVAT GSPFAPVEIN GRTVHIAQCN NSYIFPGIGL GVVACKASRI 

       490        500        510        520        530        540 
TDRMLMAASN ALAECSPMVT GQGDAVLPPL KEIQQVSRKI ALAVAKEAQA EGLALETSEE 

       550        560 
ALLEAIERNF WLPGYRAYRR RSV
Q48LC8 in FASTA format

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