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[1]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1371/journal.pgen.0010065; PubMed=16311624 [NCBI, ExPASy, EBI, Israel, Japan]
Wu M.,
Ren Q.,
Durkin A.S.,
Daugherty S.C.,
Brinkac L.M.,
Dodson R.J.,
Madupu R.,
Sullivan S.A.,
Kolonay J.F.,
Nelson W.C.,
Tallon L.J.,
Jones K.M.,
Ulrich L.E.,
Gonzalez J.M.,
Zhulin I.B.,
Robb F.T.,
Eisen J.A.;
"Life in hot carbon monoxide: the complete genome sequence of Carboxydothermus hydrogenoformans Z-2901.";
PLoS Genet. 1:563-574(2005).
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- FUNCTION: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (By similarity).
- CATALYTIC ACTIVITY: Glycine + H-protein-lipoyllysine = H-protein-S-aminomethyldihydrolipoyllysine + CO2.
- SUBUNIT: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is an heterodimer of two subunits (By similarity).
- SIMILARITY: Belongs to the gcvP family. N-terminal subunit subfamily.
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Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms.
Distributed under the Creative Commons Attribution-NoDerivs License.
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| Length: 444 AA [This is the length of the unprocessed precursor] |
Molecular weight: 48908 Da [This is the MW of the unprocessed precursor] |
CRC64: A9A0197BAEEB89D9 [This is a checksum on the sequence] |
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10 20 30 40 50 60
MKYTPHTPDE VREMLSSLGL SSIEELFSDI PEEVKLKRPL NLPSGMSELE VKKHLANLAA
70 80 90 100 110 120
KNGSADKYTV FLGAGVYDHY VPAVVNHILL RSEFYTAYTP YQAEMSQGVL QSIFEYQTMI
130 140 150 160 170 180
CELTGLDITN ASMYDGGSAL AEAALMAVSQ TRRDKVLVLA TVHPEYRSVV KTYTWGPEIE
190 200 210 220 230 240
VVEVPYKSGT VDLEKLEELI DDKTAAVLVQ HPNFFGQLEP VEEISRLIHA QKGLLVVAVD
250 260 270 280 290 300
PISLGILKPP AEYGADIAVG DGQALGNGLA FGGPHLGFFA ARKDLARRMP GRLVGLTTDK
310 320 330 340 350 360
EGNRGFVLTL QAREQHIRRE KATSNICSNQ ALNALAATVY LATVGKKGLK EIALQSLQKA
370 380 390 400 410 420
HYAFERLIGE GYEPLFSGPF FKEFVVKVKN EEEITQKLLK HHILAGPGIS RFYPELAPAL
430 440
MIAVTEKRTR EEIDNLVEVL GGDR
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Q3AET5 in FASTA format |
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