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UniProtKB/Swiss-Prot entry Q39090


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name UFO_ARATH
Primary accession number Q39090
Secondary accession numbers Q4PT17 Q9FYI4
Integrated into Swiss-Prot on May 9, 2003
Sequence was last modified on May 9, 2003 (Sequence version 2)
Annotations were last modified on    April 29, 2008 (Entry version 61)
Name and origin of the protein
Protein name Protein UNUSUAL FLORAL ORGANS
Synonyms F-box only protein 1
AtFBX1
Gene name
Name: UFO
Synonyms: FBX1
OrderedLocusNames: At1g30950
ORFNames: F17F8.16
From
Arabidopsis thaliana (Mouse-ear cress) [TaxID: 3702] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND CHARACTERIZATION.
STRAIN=cv. Landsberg erecta;
DOI=10.1105/tpc.7.9.1501; PubMed=8589630 [NCBI, ExPASy, EBI, Israel, Japan]
Ingram G.C., Goodrich J., Wilkinson M.D., Simon R., Haughn G.W., Coen E.S.;
"Parallels between UNUSUAL FLORAL ORGANS and FIMBRIATA, genes controlling flower development in Arabidopsis and Antirrhinum.";
Plant Cell 7:1501-1510(1995).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
DOI=10.1038/35048500; PubMed=11130712 [NCBI, ExPASy, EBI, Israel, Japan]
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.;
"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
Nature 408:816-820(2000).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=cv. Columbia;
Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W., Redman J.C., Wu H.C., Utterback T., Town C.D.;
Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
[4]
FUNCTION.
PubMed=8565821 [NCBI, ExPASy, EBI, Israel, Japan]
Krizek B.A., Meyerowitz E.M.;
"The Arabidopsis homeotic genes APETALA3 and PISTILLATA are sufficient to provide the B class organ identity function.";
Development 122:11-22(1996).
[5]
FUNCTION, AND DEVELOPMENTAL STAGE.
DOI=10.1016/S0960-9822(06)00053-4; PubMed=9016705 [NCBI, ExPASy, EBI, Israel, Japan]
Lee I., Wolfe D.S., Nilsson O., Weigel D.;
"A LEAFY co-regulator encoded by UNUSUAL FLORAL ORGANS.";
Curr. Biol. 7:95-104(1997).
[6]
FUNCTION.
DOI=10.1046/j.1365-313x.1999.00617.x; PubMed=10607296 [NCBI, ExPASy, EBI, Israel, Japan]
Samach A., Klenz J.E., Kohalmi S.E., Risseeuw E., Haughn G.W., Crosby W.L.;
"The UNUSUAL FLORAL ORGANS gene of Arabidopsis thaliana is an F-box protein required for normal patterning and growth in the floral meristem.";
Plant J. 20:433-445(1999).
[7]
GENE FAMILY, AND NOMENCLATURE.
DOI=10.1016/S1360-1385(00)01769-6; PubMed=11077244 [NCBI, ExPASy, EBI, Israel, Japan]
Xiao W., Jang J.-C.;
"F-box proteins in Arabidopsis.";
Trends Plant Sci. 5:454-457(2000).
[8]
SUBUNIT.
PubMed=11526079 [NCBI, ExPASy, EBI, Israel, Japan]
Zhao D., Yu Q., Chen M., Ma H.;
"The ASK1 gene regulates B function gene expression in cooperation with UFO and LEAFY in Arabidopsis.";
Development 128:2735-2746(2001).
[9]
INTERACTION WITH SKP1, AND DOMAIN.
DOI=10.1073/pnas.1033043100; PubMed=12826617 [NCBI, ExPASy, EBI, Israel, Japan]
Durfee T., Roe J.L., Sessions R.A., Inouye C., Serikawa K., Feldmann K.A., Weigel D., Zambryski P.C.;
"The F-box-containing protein UFO and AGAMOUS participate in antagonistic pathways governing early petal development in Arabidopsis.";
Proc. Natl. Acad. Sci. U.S.A. 100:8571-8576(2003).
Comments
  • FUNCTION: Considered as a meristem identity factor required for normal growth of the young floral meristem. Acts together with LEAFY to positively regulate the B class floral homeotic genes APETALA3 and PISTILLATA. In this way, operates as a region-specific regulator for petal and stamen development. Alternatively, may play a role as a negative regulator of the C class floral homeotic genes. Interacts together with the SKP1-like protein ASK1 to form a ubiquitin E3 ligase complex and could indirectly promote the ubiquitination and degradation of specific proteins controlling the floral primordia development like repressors of B class floral homeotic genes.
  • SUBUNIT: Part of a putative SCF (SKP1/Cullin/F-box) ubiquitin ligase complex. Interacts with SKP1.
  • INTERACTION:
    O49484:AT4g34210; NbExp=2; IntAct=EBI-590758, EBI-401185;
    Q00958:LFY; NbExp=3; IntAct=EBI-590758, EBI-1644366;
    Q39255:SKP1A; NbExp=4; IntAct=EBI-590758, EBI-532357;
    Q9FHW7:SKP1B; NbExp=2; IntAct=EBI-590758, EBI-604076;
  • SUBCELLULAR LOCATION: Nucleus (Probable).
  • DEVELOPMENTAL STAGE: Detected early throughout the shoot apical meristem, but not in the emerging leaf primordia. Restricted later to the junction between sepal and petal primordia.
  • MISCELLANEOUS: Mutations in the UFO gene result in the formation of unusual floral organs.
  • SIMILARITY: Contains 1 F-box domain.
  • WEB RESOURCE: Name=PlantsUBQ; Note=A functional genomics database for the ubiquitin/26S proteasome proteolytic pathway in plants; URL="http://plantsubq.genomics.purdue.edu/";.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
X89224; CAA61508.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AC000107; AAF98199.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
DQ056469; AAY78626.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S57710; S57710.
RefSeq NP_564368.1; -.
UniGene At.51845
3D structure databases
ModBase Q39090.
Protein-protein interaction databases
IntAct Q39090; -.
Organism-specific databases
TAIR At1g30950; -.
Gene expression databases
ArrayExpress Q39090; -.
GermOnline AT1G30950; Arabidopsis thaliana.
Ontologies
GO
GO:0005515; Molecular function: protein binding (inferred from physical interaction from IntAct).
QuickGo view.
Family and domain databases
InterPro IPR001810; F-box.
Graphical view of domain structure.
Pfam PF00646; F-box; 1.
Pfam graphical view of domain structure.
SMART SM00256; FBOX; 1.
SMART graphical view of domain structure.
PROSITE PS50181; FBOX; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q39090.
Genome annotation databases
GeneID 839982; -.
GenomeReviews CT485782_GR; AT1G30950.
KEGG ath:AT1G30950; -.
NMPDR fig|3702.1.peg.3439; -.
Other
ProtoNet Q39090.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Activator; Complete proteome; Developmental protein; Differentiation; Flowering; Nucleus; Transcription; Transcription regulation; Ubl conjugation pathway.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom  To Length Description FTId
CHAIN   1   442  442     Protein UNUSUAL FLORAL ORGANS. PRO_0000119966
DOMAIN   44    90  47     F-box. 
CONFLICT   44    44        G -> C (in Ref. 1; CAA61508). 
Sequence information
Length: 442 AA [This is the length of the unprocessed precursor] Molecular weight: 49047 Da [This is the MW of the unprocessed precursor] CRC64: 6E5C38B0F92AE8B7 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MDSTVFINNP SLTLPFSYTF TSSSNSSTTT STTTDSSSGQ WMDGRIWSKL PPPLLDRVIA 

        70         80         90        100        110        120 
FLPPPAFFRT RCVCKRFYSL LFSNTFLETY LQLLPLRHNC FLFFKHKTLK SYIYKRGGTN 

       130        140        150        160        170        180 
DDDSNKAEGF LFDPNEIRWY RLSFAYIPSG FYPSGSSGGL VSWVSEEAGL KTILLCNPLV 

       190        200        210        220        230        240 
GSVSQLPPIS RPRLFPSIGL SVTPTSIDVT VAGDDLISPY AVKNLSSESF HVDAGGFFSL 

       250        260        270        280        290        300 
WAMTSSLPRL CSLESGKMVY VQGKFYCMNY SPFSVLSYEV TGNRWIKIQA PMRRFLRSPS 

       310        320        330        340        350        360 
LLESKGRLIL VAAVEKSKLN VPKSLRLWSL QQDNATWVEI ERMPQPLYTQ FAAEEGGKGF 

       370        380        390        400        410        420 
ECVGNQEFVM IVLRGTSLQL LFDIVRKSWL WVPPCPYSGS GGGSSGGGSD GEVLQGFAYD 

       430        440 
PVLTTPVVSL LDQLTLPFPG VC 

Q39090 in FASTA format

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