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UniProtKB/Swiss-Prot entry Q2IIA8


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name DNAE2_ANADE
Primary accession number Q2IIA8
Secondary accession numbers None
Integrated into Swiss-Prot on May 20, 2008
Sequence was last modified on March 7, 2006 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 21)
Name and origin of the protein
Protein name Error-prone DNA polymerase
Synonym EC 2.7.7.7
Gene name
Name: dnaE2
OrderedLocusNames: Adeh_1612
From
Anaeromyxobacter dehalogenans (strain 2CP-C) [TaxID: 290397] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Deltaproteobacteria; Myxococcales; Cystobacterineae; Myxococcaceae; Anaeromyxobacter.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Kiss H., Schmutz J., Larimer F., Land M., Kyrpides N., Anderson I., Sanford R.A., Ritalahti K.M., Thomas H.S., Kirby J.R., Zhulin I.B., Loeffler F.E., Richardson P.;
"Complete sequence of Anaeromyxobacter dehalogenans 2CP-C.";
Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000251; ABC81385.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_464822.1; -.
3D structure databases
ModBase Q2IIA8.
Enzyme and pathway databases
BioCyc ADEH290397:ADEH_1612-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0008408; Molecular function: 3'-5' exonuclease activity (inferred from electronic annotation from InterPro).
GO:0003677; Molecular function: DNA binding (inferred from electronic annotation from InterPro).
GO:0003887; Molecular function: DNA-directed DNA polymerase activity (inferred from electronic annotation from HAMAP).
GO:0006260; Biological process: DNA replication (inferred from electronic annotation from InterPro).
GO:0045020; Biological process: error-prone DNA repair (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01902; -; 1.
PBIL [Tree]
InterPro IPR011708; DNA_pol3_alpha.
IPR004365; NA_bd_OB_tRNA-helicase.
IPR004013; PHP_C.
IPR003141; PHP_N.
IPR004805; PolC_alpha.
Graphical view of domain structure.
Pfam PF07733; DNA_pol3_alpha; 1.
PF02811; PHP; 1.
PF01336; tRNA_anti; 1.
Pfam graphical view of domain structure.
SMART SM00481; POLIIIAc; 1.
SMART graphical view of domain structure.
TIGRFAMs TIGR00594; polc; 1.
ProtoNet Q2IIA8.
Genome annotation databases
GeneID 3888111; -.
GenomeReviews CP000251_GR; Adeh_1612.
KEGG ade:Adeh_1612; -.
Phylogenomic databases
HOGENOM Q2IIA8; -.
Genome annotation databases
CMR Q2IIA8; Adeh_1612.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; DNA damage; DNA repair; DNA replication; DNA-directed DNA polymerase; Nucleotidyltransferase; Transferase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   1132  1132     Error-prone DNA polymerase. PRO_1000088470
Sequence information
Length: 1132 AA [This is the length of the unprocessed precursor] Molecular weight: 121076 Da [This is the MW of the unprocessed precursor] CRC64: 27804FBFF75A32F5 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSHAPRYAEL RCKSCFSFLE GASHPEELVG RAAELGLSGL ALADVNGLYG IVRAHAEAKR 

        70         80         90        100        110        120 
QGLPLIVGAE LVVAGLAPGR PARLVLLAQD REGYAGLCRL VTRAHCGEGW TGAPPRRERD 

       130        140        150        160        170        180 
AVAVPFEAVA AGARGLFALY PGADGDAVAR LKDAFGRRAA LAVARHRVAG EEARVLAARS 

       190        200        210        220        230        240 
AGRRLGVPVA VTNDVHTHAR ARQVLQDVLT CVRHGTTVDR AGRRLFPNAE RTLKGPEELA 

       250        260        270        280        290        300 
RLWSDFPEGL AAAADIADQC RFRMEEIRGE HPLPPVVVER GGLAGGVEVA TSSPAQAARD 

       310        320        330        340        350        360 
GARSTTPSLR LRASLPAEPP AAPAPEAPAA AAAPGLAASA ASVAADTGAD RDGALAGMAL 

       370        380        390        400        410        420 
LRELVREGAR WRYGGEPPED VARQLARELD LVESLGYASY FLTVWDVVRF ARSRGILCQG 

       430        440        450        460        470        480 
RGSAANSAVC YVLGITSIDP VRMGLLFERF ISAERGEPPD IDVDFEHERR EEVLQYVYQR 

       490        500        510        520        530        540 
YGRDRAGMVC EVITYRGKSA LRDVGKALGL SLGQVDRLAK LVGSYEDLGQ VGPELLAQAG 

       550        560        570        580        590        600 
LDAADSERVR MTLALARELQ GFPRHLSIHV GGFVITRRPL CETVPIEPAA MPGRTIVQWD 

       610        620        630        640        650        660 
KDDLAELDLL KVDLLGLGML TALSRALALL ARHRPAPASP TPVPHPDALA TIPAEDPEVY 

       670        680        690        700        710        720 
EMLGRADSIG VFQVESRAQM SLAPRLRPRN FYDLVISVAI IRPGPIQGGM IHPYLRRRDG 

       730        740        750        760        770        780 
KEQVRYPYAP LEPVLARTLG VPLFQEQAMR LAVIAAGFTP GEADELRRVM THRRSHEKLA 

       790        800        810        820        830        840 
AMKARLVAGM AERGISGADA EEIFKQLLGF AGYGFPESHA ASFALLVYAS AWLKRYHPAA 

       850        860        870        880        890        900 
FACALLNSQP MGFYAPHTLV EDAKRHGVEV RGVDVGCSGW ESSLEGAAPG RPAAPGEAAV 

       910        920        930        940        950        960 
LRVGLHAIRG LPRAVGEAIL EARAAGPFGS VAELVRRARL SRAWLVRLAE AGALGTLAPD 

       970        980        990       1000       1010       1020 
RRGAVWRSLA VEADGGDLFA GLAPPEPEAA LPEASAADEV SADFTTTGLS VRGHPMALVR 

      1030       1040       1050       1060       1070       1080 
PGLGGDRIRT ARELGRLPDR APVEVAGLVI VRQRPETARG IVFVSLEDET GIANLVVMPD 

      1090       1100       1110       1120       1130 
VYERFRPVVR GAPFLLARGR VERSGKVVNV RVDSVAPLAL APSMDARARD FH 

Q2IIA8 in FASTA format

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