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UniProtKB/Swiss-Prot entry Q10062


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PPOX_SCHPO
Primary accession number Q10062
Secondary accession numbers None
Integrated into Swiss-Prot on February 1, 1996
Sequence was last modified on February 1, 1996 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 49)
Name and origin of the protein
Protein name Protoporphyrinogen oxidase
Synonyms PPO
EC 1.3.3.4
Gene name
Name: hem14
ORFNames: SPAC1F5.07c
From
Schizosaccharomyces pombe (Fission yeast) [TaxID: 4896] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 38366 / 972;
DOI=10.1038/nature724; PubMed=11859360 [NCBI, ExPASy, EBI, Israel, Japan]
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M., Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.;
"The genome sequence of Schizosaccharomyces pombe.";
Nature 415:871-880(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CU329670; CAA92235.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T38088; T38088.
RefSeq NP_592866.1; -.
3D structure databases
ModBase Q10062.
Enzyme and pathway databases
BioCyc SPOM-XXX-01:SPOM-XXX-01-000601-MON; -.
Organism-specific databases
GeneDB_Spombe SPAC1F5.07c; -.
Gene expression databases
ArrayExpress Q10062; -.
Ontologies
GO
GO:0005829; Cellular component: cytosol (inferred from direct assay from GeneDB_SPombe).
GO:0005634; Cellular component: nucleus (inferred from direct assay from GeneDB_SPombe).
QuickGo view.
Family and domain databases
InterPro IPR000759; Adrndx_reductase.
IPR006076; FAD-dep_OxRdtase.
IPR004572; Proto_IX_ox.
Graphical view of domain structure.
Pfam PF01266; DAO; 1.
Pfam graphical view of domain structure.
PRINTS PR00419; ADXRDTASE.
TIGRFAMs TIGR00562; proto_IX_ox; 1.
BLOCKS Q10062.
ProtoNet Q10062.
Genome annotation databases
GeneID 2541631; -.
KEGG spo:SPAC1F5.07c; -.
NMPDR fig|4896.1.peg.2836; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; FAD; Flavoprotein; Heme biosynthesis; Mitochondrion; Oxidoreductase; Porphyrin biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   490  490     Protoporphyrinogen oxidase. PRO_0000116445
NP_BIND   7    12  6     FAD (Potential). 
Sequence information
Length: 490 AA [This is the length of the unprocessed precursor] Molecular weight: 53462 Da [This is the MW of the unprocessed precursor] CRC64: CB679F6A437547AA [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSIAICGGGI AGLSTAFYLA RLIPKCTIDL YEKGPRLGGW LQSVKIPCAD SPTGTVLFEQ 

        70         80         90        100        110        120 
GPRTLRPAGV AGLANLDLIS KLGIEDKLLR ISSNSPSAKN RYIYYPDRLN EIPSSILGSI 

       130        140        150        160        170        180 
KSIMQPALRP MPLAMMLEPF RKSKRDSTDE SVGSFMRRRF GKNVTDRVMS AMINGIYAGD 

       190        200        210        220        230        240 
LNDLSMHSSM FGFLAKIEKK YGNITLGLIR ALLAREILSP AEKALKAALL AEPKTAELSN 

       250        260        270        280        290        300 
SMKSTSMFAF KEGIETITLS IADELKKMPN VKIHLNKPAK TLVPHKTQSL VDVNGQAYEY 

       310        320        330        340        350        360 
VVFANSSRNL ENLISCPKME TPTSSVYVVN VYYKDPNVLP IRGFGLLIPS CTPNNPNHVL 

       370        380        390        400        410        420 
GIVFDSEQNN PENGSKVTVM MGGSAYTKNT SLIPTNPEEA VNNALKALQH TLKISSKPTL 

       430        440        450        460        470        480 
TNATLQQNCI PQYRVGHQDN LNSLKSWIEK NMGGRILLTG SWYNGVSIGD CIMNGHSTAR 

       490 
KLASLMNSSS 

Q10062 in FASTA format

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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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