[1]	NUCLEOTIDE SEQUENCE [GENOMIC DNA]. STRAIN=A4; PubMed=1932811 [NCBI, ExPASy, EBI, Israel, Japan] Camilleri C., Jouanin L.; "The TR-DNA region carrying the auxin synthesis genes of the Agrobacterium rhizogenes agropine-type plasmid pRiA4: nucleotide sequence analysis and introduction into tobacco plants."; Mol. Plant Microbe Interact. 4:155-162(1991).
[2]	NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-12. STRAIN=A4; PubMed=8510649 [NCBI, ExPASy, EBI, Israel, Japan] Gaudin V., Camilleri C., Jouanin L.; "Multiple regions of a divergent promoter control the expression of the Agrobacterium rhizogenes aux1 and aux2 plant oncogenes."; Mol. Gen. Genet. 239:225-234(1993).

Comments

CATALYTIC ACTIVITY: L-tryptophan + O₂ = (indol-3-yl)acetamide + CO₂ + H₂O.
PATHWAY: Plant hormone metabolism; auxin biosynthesis .
SIMILARITY: Belongs to the tryptophan 2-monooxygenase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

M61151; AAA22080.1; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]
S62276; AAP13934.1; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

I39708; I39708.

3D structure databases

ModBase

Q09109.

Ontologies

GO:0009055;	Molecular function: electron carrier activity (inferred from electronic annotation from InterPro).
GO:0050361;	Molecular function: tryptophan 2-monooxygenase activity (inferred from electronic annotation from InterPro).
GO:0009851;	Biological process: auxin biosynthetic process (inferred from electronic annotation from InterPro).
GO:0055114;	Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.

Family and domain databases

InterPro

IPR000759; Adrndx_reductase.
IPR002937; Amino_oxidase.
IPR006064; Glycosidase.
IPR012142; Trp_2-mOase.
Graphical view of domain structure.

Pfam

PF01593; Amino_oxidase; 1.
PF02027; RolB_RolC; 1.
Pfam graphical view of domain structure.

PIRSF

PIRSF000319; Trp_2-mono_O2ase; 1.

PR00419; ADXRDTASE.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Auxin biosynthesis; Monooxygenase; Oxidoreductase; Plasmid.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 749`	`749`		`Tryptophan 2-monooxygenase.`	`PRO_0000065585`

Sequence information

Length: 749 AA [This is the length of the unprocessed precursor]

Molecular weight: 83178 Da [This is the MW of the unprocessed precursor]

CRC64: 8B7793970206F97B [This is a checksum on the sequence]

        10         20         30         40         50         60 
MAGSSFTLPS TGSAPLDMML IDDSDLLQLG LQQVFSKRYT ETPQSRYKLT RRASPDVSSG 

        70         80         90        100        110        120 
EGNVHALAFI YVNAETLQMI KNARSLTEAN GVKDLVAIDV PPFRNDFSRA LLLQVINLLG 

       130        140        150        160        170        180 
NNRNADDDLS HFIAVALPNS ARSKILTTAP FEGSLSENFR GFPITREGNV ACEVLAYGNN 

       190        200        210        220        230        240 
LMPKACSDSF PTVDLLYDYG KFFESCAADG RIGYFPEGVT KPKVAIIGAG FSGLVAASEL 

       250        260        270        280        290        300 
LHAGVDDVTV YEASDRLGGK LWSHGFKSAP NVIAEMGAMR FPRSESCLFF YLKKHGLDSV 

       310        320        330        340        350        360 
GLFPNPGSVD TALFYRGRQY IWKAGEEPPE LFRRVHHGWR AFLQDGYLHD GVMLASPLAI 

       370        380        390        400        410        420 
VDALNLGHLQ QAHGFWQSWL TYFERESFSS GIEKMFLGNH PPGGEQWNSL DDLDLFKALG 

       430        440        450        460        470        480 
IGSGGFGPVF ESGFIEILRL VVNGYEDNVR LSYEGISELP HRIASQVING RSIRERTIHV 

       490        500        510        520        530        540 
QVEQIDREED KINIKIKGGK VEVYDRVLVT SGFANIEMRH LLTSSNAFFH ADVSHAIGNS 

       550        560        570        580        590        600 
HMTGASKLFL LTNEKFWLQH HLPSCILTTG VAKAVYCLDY DPRDPSGKGL VLISYTWEDD 

       610        620        630        640        650        660 
SHKLLAVPDK RERFASLQRD IGRAFPDFAK HLTPADGNYD DNIVQHDWLT DPHAGGAFKL 

       670        680        690        700        710        720 
NRRGNDVYSE RLFFQPFDVM HPADDKGLYL AGCSCSFTGG WVHGAIQTAC NATCAIIYGS 

       730        740 
GHLQELIHWR HLKEGNPLAH AWKRYRYQA

Q09109 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools