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UniProtKB/Swiss-Prot entry Q08062

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name MDHC_MAIZE
Primary accession number Q08062
Secondary accession numbers None
Integrated into Swiss-Prot on December 1, 2000
Sequence was last modified on November 1, 1998 (Sequence version 2)
Annotations were last modified on    November 25, 2008 (Entry version 73)
Name and origin of the protein
Protein name Malate dehydrogenase, cytoplasmic
Synonym EC 1.1.1.37
Gene name None
From
Zea mays (Maize) [TaxID: 4577] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae; PACCAD clade; Panicoideae; Andropogoneae; Zea.
Protein existence 2: Evidence at transcript level;
References
[1]
 NUCLEOTIDE SEQUENCE [MRNA].
STRAIN=cv. Yedan 4;
TISSUE=Leaf;
Hu J., Zhao X., Yuan Z., Qian X., Yang J.;
"Cloning and characterization of cytoplasmic malate dehydrogenase over-expressed in hybrid maize.";
Submitted (JUL-1997) to the EMBL/GenBank/DDBJ databases.
[2]
 NUCLEOTIDE SEQUENCE [MRNA] OF 4-73.
TISSUE=Leaf, and Sheath;
DOI=10.1104/pp.101.1.329; PubMed=8278499 [NCBI, ExPASy, EBI, Israel, Japan]
Keith C.S., Hoang D.O., Barrett B.M., Feigelman B., Nelson M.C., Thai H., Baysdorfer C.;
"Partial sequence analysis of 130 randomly selected maize cDNA clones.";
Plant Physiol. 101:329-332(1993).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AF007581; AAB64290.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
M95069; AAA18556.2; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T02935; T02935.
T03650; T03650.
RefSeq NP_001105603.1; -.
UniGene Zm.82624
3D structure databases
HSSP P11708; 4MDH. [HSSP ENTRY / PDB]
ModBase Q08062.
Organism-specific databases
Gramene Q08062; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from UniProtKB-KW).
GO:0005488; Molecular function: binding (inferred from electronic annotation from InterPro).
GO:0030060; Molecular function: L-malate dehydrogenase activity (inferred from electronic annotation from InterPro).
GO:0006096; Biological process: glycolysis (inferred from electronic annotation from InterPro).
GO:0006108; Biological process: malate metabolic process (inferred from electronic annotation from InterPro).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0006099; Biological process: tricarboxylic acid cycle (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR001557; L-lactate/malate_DHase.
IPR001236; Lactate/malate_DHase.
IPR015955; Lactate_DHase/Glyco_Ohase_4_C.
IPR001252; Malate_DHase_AS.
IPR011274; Malate_DHase_NAD-dep_euk.
IPR010945; Malate_DHase_SF1.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.90.110.10; lact_mal_DH; 1.
G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR23382; MDH_SF1; 1.
Pfam PF02866; Ldh_1_C; 1.
PF00056; Ldh_1_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000102; Lac_mal_DH; 1.
ProDom PD003052; Mal_dehydrog; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR01759; MalateDH-SF1; 1.
TIGR01758; MDH_euk_cyt; 1.
PROSITE PS00068; MDH; 1.
ProtoNet Q08062.
Genome annotation databases
GeneID 542598; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Cytoplasm; NAD; Oxidoreductase; Tricarboxylic acid cycle.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   332  332     Malate dehydrogenase, cytoplasmic. PRO_0000113415
NP_BIND   12    18  7     NAD (By similarity). 
NP_BIND   130   132  3     NAD (By similarity). 
ACT_SITE   188   188        Proton acceptor (By similarity). 
BINDING   93    93        Substrate (By similarity). 
BINDING   99    99        Substrate (By similarity). 
BINDING   106   106        NAD (By similarity). 
BINDING   113   113        NAD (By similarity). 
BINDING   132   132        Substrate (By similarity). 
BINDING   163   163        Substrate (By similarity). 
Sequence information
Length: 332 AA [This is the length of the unprocessed precursor] Molecular weight: 35590 Da [This is the MW of the unprocessed precursor] CRC64: 05D82B33FF0CE26F [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MAKEPMRVLV TGAAGQIGYA LVPMIARGVM LGADQPVILH MLDIPPAAEA LNGVKMELVD 

        70         80         90        100        110        120 
AAFPLLKGVV ATTDVVEACT GVNVAVMVGG FPRKEGMERK DVMSKNVSIY KSQASALEAH 

       130        140        150        160        170        180 
AAPNCKVLVV ANPANTNALI LKEFAPSIPE KNVTCLTRLD HNRALGQISE RLNVQVSDVK 

       190        200        210        220        230        240 
NVIIWGNHSS SQYPDVNHAT VKTSTGEKPV RELVSDDEWL NGEFITTVQQ RGAAIIKARK 

       250        260        270        280        290        300 
FSSALSAASS ACDHIRDWVL GTPEGTFVSM GVYSDGSYGV PSGLIYSFPV TCSGGEWKIV 

       310        320        330 
QGLPIDEFSR KKMDATAQEL TEEKTLAYSC LE
Q08062 in FASTA format

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