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UniProtKB/Swiss-Prot entry Q07288

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ADH1_KLUMA
Primary accession number Q07288
Secondary accession numbers None
Integrated into Swiss-Prot on February 1, 1995
Sequence was last modified on February 1, 1995 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 47)
Name and origin of the protein
Protein name Alcohol dehydrogenase 1
Synonym EC 1.1.1.1
Gene name
Name: ADH1
From
Kluyveromyces marxianus (Yeast) (Candida kefyr) [TaxID: 4911] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=ATCC 12424 / NRRL Y-610;
PubMed=8485163 [NCBI, ExPASy, EBI, Israel, Japan]
Ladriere J.-M., Delcour J., Vandenhaute J.;
"Sequence of a gene coding for a cytoplasmic alcohol dehydrogenase from Kluyveromyces marxianus ATCC 12424.";
Biochim. Biophys. Acta 1173:99-101(1993).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
X60224; CAA42785.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S32521; S32521.
3D structure databases
HSSP P39462; 1JVB. [HSSP ENTRY / PDB]
SMR Q07288; 2-348.
ModBase Q07288.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from UniProtKB-KW).
GO:0004022; Molecular function: alcohol dehydrogenase activity (inferred from electronic annotation from EC).
GO:0008270; Molecular function: zinc ion binding (inferred from electronic annotation from InterPro).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
InterPro IPR013154; AlcDHase_GroES-like.
IPR002085; AlcDHase_SF_Zn.
IPR013149; AlcDHase_Zn-bd.
IPR002328; AlcDHase_Zn_CS.
Graphical view of domain structure.
PANTHER PTHR11695; ADH_Sf_Zn; 1.
Pfam PF08240; ADH_N; 1.
PF00107; ADH_zinc_N; 1.
Pfam graphical view of domain structure.
PROSITE PS00059; ADH_ZINC; 1.
ProtoNet Q07288.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Cytoplasm; Metal-binding; NAD; Oxidoreductase; Zinc.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   348  348     Alcohol dehydrogenase 1. PRO_0000160724
METAL   44    44        Zinc 1; catalytic (By similarity). 
METAL   67    67        Zinc 1; catalytic (By similarity). 
METAL   98    98        Zinc 2 (By similarity). 
METAL   101   101        Zinc 2 (By similarity). 
METAL   104   104        Zinc 2 (By similarity). 
METAL   112   112        Zinc 2 (By similarity). 
METAL   154   154        Zinc 1; catalytic (By similarity). 
Sequence information
Length: 348 AA [This is the length of the unprocessed precursor] Molecular weight: 37159 Da [This is the MW of the unprocessed precursor] CRC64: A75D2EBE82E355BD [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MAIPETQKGV IFYEHGGELQ YKDIPVPKPK PNELLINVKY SGVCHTDLHA WQGDWPLDTK 

        70         80         90        100        110        120 
LPLVGGHEGA GIVVAMGENV TGWEIGDYAG IKWLNGSCMS CEECELSNEP NCPKADLSGY 

       130        140        150        160        170        180 
THDGSFQQYA TADAVQAARI PKNVDLAEVA PILCAGVTVY KALKSAHIKA GDWVAISGAC 

       190        200        210        220        230        240 
GGLGSLAIQY AKAMGYRVLG IDAGDEKAKL FKELGGEYFI DFTKTKDMVA EVIEATNGVA 

       250        260        270        280        290        300 
HAVINVSVSE AAISTSVLYT RSNGTVVLVG LPRDAQCKSD VFNQVVKSIS IVGSYVGNRA 

       310        320        330        340 
DTREALDFFS RGLVKAPIKI LGLSELASVY DKMVKGQIVG RIVVDTSK
Q07288 in FASTA format

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