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UniProtKB/Swiss-Prot entry Q04616

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name 3O1D_RHOOP
Primary accession number Q04616
Secondary accession numbers None
Integrated into Swiss-Prot on June 1, 1994
Sequence was last modified on January 23, 2007 (Sequence version 3)
Annotations were last modified on    November 25, 2008 (Entry version 49)
Name and origin of the protein
Protein name 3-oxosteroid 1-dehydrogenase
Synonym EC 1.3.99.4
Gene name None
From
Rhodococcus opacus (Nocardia opaca) [TaxID: 37919] 
Taxonomy Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; Corynebacterineae; Nocardiaceae; Rhodococcus.
Protein existence 1: Evidence at protein level;
References
[1]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=IMET 7030;
Drobnic K.;
Submitted (JUN-1996) to the EMBL/GenBank/DDBJ databases.
[2]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-57, AND PROTEIN SEQUENCE OF 2-15.
DOI=10.1006/bbrc.1993.1077; PubMed=7916596 [NCBI, ExPASy, EBI, Israel, Japan]
Drobnic K., Krizaj I., Gubensek F., Komel R.;
"Improved purification of steroid 1:2-dehydrogenase from Nocardia opaca and partial characterization of its cloned gene sequence.";
Biochem. Biophys. Res. Commun. 190:509-515(1993).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
U59422; AAB02831.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR PC1242; PC1242.
3D structure databases
ModBase Q04616.
Ontologies
GO
GO:0005886; Cellular component: plasma membrane (inferred from electronic annotation from UniProtKB-KW).
GO:0047571; Molecular function: 3-oxosteroid 1-dehydrogenase activity (inferred from electronic annotation from EC).
GO:0009055; Molecular function: electron carrier activity (inferred from electronic annotation from InterPro).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0008202; Biological process: steroid metabolic process (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR003953; FAD_bind2_N.
Graphical view of domain structure.
Pfam PF00890; FAD_binding_2; 1.
Pfam graphical view of domain structure.
ProtoNet Q04616.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Cell inner membrane; Cell membrane; Direct protein sequencing; FAD; Flavoprotein; Lipid metabolism; Membrane; Oxidoreductase; Steroid metabolism.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
INIT_MET   1     1        Removed. 
CHAIN   2   507  506     3-oxosteroid 1-dehydrogenase. PRO_0000064377
NP_BIND   9    38  30     FAD (By similarity). 
Sequence information
Length: 507 AA [This is the length of the unprocessed precursor] Molecular weight: 54005 Da [This is the MW of the unprocessed precursor] CRC64: 067F865E9E7ED984 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MQDWTSECDL LVVGSGGGAL TGAYTAAAQG LTTIVLEKTD RFGGTSAYSG ASIWLPGTQV 

        70         80         90        100        110        120 
QERAGLPDST ENARSYLRAL LGDAESERQD AYVETAPAVV ALLEQNPNIE FEFRAFPDYY 

       130        140        150        160        170        180 
KAEGRMDTGR SINPLDLDPA DIGDLAGRCV RNCTKTDRMD HAPGRMIGGR ALIAVSAAVQ 

       190        200        210        220        230        240 
STARQNFAPE SVLTSLIVED GRVVGGLRSN PRYRQRIKAN RGVLMHAGGG FEGNAEMREQ 

       250        260        270        280        290        300 
AGTPGKAIWS MGPSGPTPAT RSPPELAGRR RNSLARSGVV LPRGRAARRR RLHGRVRGGL 

       310        320        330        340        350        360 
VVDSPGSVPQ RVASVRPVRT SHGCSPDDNG SAVPSFMIFD SREVTDCPPS ASRTRPPPST 

       370        380        390        400        410        420 
SKPEPGSVPT LSKNSLPRPD YRPERIAQHC RKVQRCRKLG VDEEFHRGED PYDAFFCPPN 

       430        440        450        460        470        480 
GGANAALTAI ENGPFYAARD RLSDLGTKGG LVTDVNGRVL RADGSAIDGL YAAGNTSASV 

       490        500 
APFYPGPGVP LGTAMVFSYR AAQDMAK
Q04616 in FASTA format

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