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UniProtKB/Swiss-Prot entry Q03GJ0


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name GUAC_PEDPA
Primary accession number Q03GJ0
Secondary accession numbers None
Integrated into Swiss-Prot on July 10, 2007
Sequence was last modified on November 14, 2006 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 15)
Name and origin of the protein
Protein name GMP reductase
Synonyms EC 1.7.1.7
Guanosine 5'-monophosphate oxidoreductase
Guanosine monophosphate reductase
Gene name
Name: guaC
OrderedLocusNames: PEPE_0595
From
Pediococcus pentosaceus (strain ATCC 25745 / 183-1w) [TaxID: 278197] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Lactobacillales; Lactobacillaceae; Pediococcus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1073/pnas.0607117103; PubMed=17030793 [NCBI, ExPASy, EBI, Israel, Japan]
Makarova K.S., Slesarev A., Wolf Y.I., Sorokin A., Mirkin B., Koonin E.V., Pavlov A., Pavlova N., Karamychev V., Polouchine N., Shakhova V., Grigoriev I., Lou Y., Rohksar D., Lucas S., Huang K., Goodstein D.M., Hawkins T., Plengvidhya V., Welker D., Hughes J., Goh Y., Benson A., Baldwin K., Lee J.-H., Diaz-Muniz I., Dosti B., Smeianov V., Wechter W., Barabote R., Lorca G., Altermann E., Barrangou R., Ganesan B., Xie Y., Rawsthorne H., Tamir D., Parker C., Breidt F., Broadbent J.R., Hutkins R., O'Sullivan D., Steele J., Unlu G., Saier M.H. Jr., Klaenhammer T., Richardson P., Kozyavkin S., Weimer B.C., Mills D.A.;
"Comparative genomics of the lactic acid bacteria.";
Proc. Natl. Acad. Sci. U.S.A. 103:15611-15616(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000422; ABJ67682.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_804124.1; -.
3D structure databases
SMR Q03GJ0; 3-319.
ModBase Q03GJ0.
Ontologies
GO
GO:0003920; Molecular function: GMP reductase activity (inferred from electronic annotation from HAMAP).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from InterPro).
GO:0006163; Biological process: purine nucleotide metabolic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01511; -; 1.
PBIL [Tree]
InterPro IPR013785; Aldolase_TIM.
IPR005994; GMP_reduct2.
IPR015875; IMP_DH/GMP_Rdtase_CS.
IPR001093; IMP_DHase_GMPRtase.
Graphical view of domain structure.
Gene3D G3DSA:3.20.20.70; Aldolase_TIM; 1.
Pfam PF00478; IMPDH; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF036500; GMP_red_Firmic; 1.
TIGRFAMs TIGR01306; GMP_reduct_2; 1.
PROSITE PS00487; IMP_DH_GMP_RED; 1.
ProtoNet Q03GJ0.
Genome annotation databases
GeneID 4418216; -.
GenomeReviews CP000422_GR; PEPE_0595.
KEGG ppe:PEPE_0595; -.
NMPDR fig|278197.10.peg.547; -.
CMR Q03GJ0; PEPE_0595.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   325  325     GMP reductase. PRO_0000294280
NP_BIND   203   226  24     NADP (Potential). 
ACT_SITE   174   174        Thioimidate intermediate (By similarity). 
Sequence information
Length: 325 AA [This is the length of the unprocessed precursor] Molecular weight: 36061 Da [This is the MW of the unprocessed precursor] CRC64: 2C83AA2A6F2CBBAA [This is a checksum on the sequence]
        10         20         30         40         50         60 
MKVFDYEDIQ LIPAKCIVRS RTECDPTVVL GEHRFKLPVV PANMQTIINE EIAEKLAEDG 

        70         80         90        100        110        120 
YFYIMHRFEP ERRMDFVKKM KDKGLISSIS VGVKDDEYAL IDQLAEENLT PDYITIDVAH 

       130        140        150        160        170        180 
GHAQSVIDMI HYIKEKLPAA FVIAGNVGTQ EGVRELENAG ADATKVGIGP GKVCITKIKT 

       190        200        210        220        230        240 
GFGTGGWQLS ALRWCAKVAR KPLIADGGIR THGDIAKSIR FGATMVMIGS LFAGHIESPG 

       250        260        270        280        290        300 
ETKVEDGVKY KEYFGSASQY QKGEAKNVEG KKIWIHQRGH LRDTLQAMRE DLQSSISYAG 

       310        320 
GRDLEAIRKV DYVIVKNSIF NGDVL 

Q03GJ0 in FASTA format

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