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UniProtKB/Swiss-Prot entry Q01158

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name LUCI_LUCLA
Primary accession number Q01158
Secondary accession numbers None
Integrated into Swiss-Prot on April 1, 1993
Sequence was last modified on April 1, 1993 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 49)
Name and origin of the protein
Protein name Luciferin 4-monooxygenase
Synonyms Luciferase
EC 1.13.12.7
Gene name None
From
Luciola lateralis (Firefly) [TaxID: 7052] 
Taxonomy Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Coleoptera; Polyphaga; Elateriformia; Elateroidea; Lampyridae; Luciolinae; Luciola.
Protein existence 2: Evidence at transcript level;
References
[1]
 NUCLEOTIDE SEQUENCE [MRNA].
DOI=10.1016/0167-4781(92)90071-7; PubMed=1610896 [NCBI, ExPASy, EBI, Israel, Japan]
Tatsumi H., Kajiyama N., Nakano E.;
"Molecular cloning and expression in Escherichia coli of a cDNA clone encoding luciferase of a firefly, Luciola lateralis.";
Biochim. Biophys. Acta 1131:161-165(1992).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
X66919; CAA47358.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S23437; S23437.
3D structure databases
HSSP P08659; 1LCI. [HSSP ENTRY / PDB]
SMR Q01158; 7-545.
ModBase Q01158.
Ontologies
GO
GO:0005777; Cellular component: peroxisome (inferred from electronic annotation from UniProtKB-KW).
GO:0000287; Molecular function: magnesium ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0047077; Molecular function: Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity (inferred from electronic annotation from EC).
GO:0008218; Biological process: bioluminescence (inferred from electronic annotation from UniProtKB-KW).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR000873; AMP-dep_Synth/Lig.
Graphical view of domain structure.
Pfam PF00501; AMP-binding; 1.
Pfam graphical view of domain structure.
PRINTS PR00154; AMPBINDING.
PROSITE PS00455; AMP_BINDING; 1.
ProtoNet Q01158.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Luminescence; Magnesium; Metal-binding; Monooxygenase; Oxidoreductase; Peroxisome; Photoprotein.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   548  548     Luciferin 4-monooxygenase. PRO_0000193144
MOTIF   546   548  3     Microbody targeting signal (Potential). 
Sequence information
Length: 548 AA [This is the length of the unprocessed precursor] Molecular weight: 60125 Da [This is the MW of the unprocessed precursor] CRC64: AC62F9320BB6D4A6 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MENMENDENI VYGPEPFYPI EEGSAGAQLR KYMDRYAKLG AIAFTNALTG VDYTYAEYLE 

        70         80         90        100        110        120 
KSCCLGEALK NYGLVVDGRI ALCSENCEEF FIPVLAGLFI GVGVAPTNEI YTLRELVHSL 

       130        140        150        160        170        180 
GISKPTIVFS SKKGLDKVIT VQKTVTAIKT IVILDSKVDY RGYQSMDNFI KKNTPQGFKG 

       190        200        210        220        230        240 
SSFKTVEVNR KEQVALIMNS SGSTGLPKGV QLTHENAVTR FSHARDPIYG NQVSPGTAIL 

       250        260        270        280        290        300 
TVVPFHHGFG MFTTLGYLTC GFRIVMLTKF DEETFLKTLQ DYKCSSVILV PTLFAILNRS 

       310        320        330        340        350        360 
ELLDKYDLSN LVEIASGGAP LSKEIGEAVA RRFNLPGVRQ GYGLTETTSA IIITPEGDDK 

       370        380        390        400        410        420 
PGASGKVVPL FKAKVIDLDT KKTLGPNRRG EVCVKGPMLM KGYVDNPEAT REIIDEEGWL 

       430        440        450        460        470        480 
HTGDIGYYDE EKHFFIVDRL KSLIKYKGYQ VPPAELESVL LQHPNIFDAG VAGVPDPIAG 

       490        500        510        520        530        540 
ELPGAVVVLE KGKSMTEKEV MDYVASQVSN AKRLRGGVRF VDEVPKGLTG KIDGKAIREI 


LKKPVAKM
Q01158 in FASTA format

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