[1]	NUCLEOTIDE SEQUENCE [MRNA]. STRAIN=Wistar; TISSUE=Brain; Ogura K.; "Expression cloning of a cDNA encoding a ganglioside expression factor-2 (GEF-2)."; Submitted (MAY-1997) to the EMBL/GenBank/DDBJ databases.
[2]	NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. TISSUE=Liver, and Pituitary; DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan] The MGC Project Team; "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."; Genome Res. 14:2121-2127(2004).

Comments

FUNCTION: Involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity).
SUBUNIT: Monomer. Interacts with GABRG2, ULK1, NSF, GOSR1 and beta-tubulin (By similarity).
SUBCELLULAR LOCATION: Golgi apparatus (By similarity).
PTM: Phosphorylated upon DNA damage, probably by ATM or ATR (By similarity).
SIMILARITY: Belongs to the MAP1 LC3 family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AB003515; BAA19975.1; -; mRNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]
BC058145; AAH58145.1; -; mRNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]
BC088139; AAH88139.1; -; mRNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]

IPI00195649; -.

NP_073197.1; -.

3D structure databases

SMR

P60522; 1-117.

ModBase

P60522.

Organism-specific databases

RGD

620510; Gabarapl2.

Gene expression databases

ArrayExpress

P60522; -.

GermOnline

ENSRNOG00000019425; Rattus norvegicus.
ENSRNOG00000033345; Rattus norvegicus.

Ontologies

GO:0005794;	Cellular component: Golgi apparatus (inferred from electronic annotation from UniProtKB-SubCell).
GO:0015031;	Biological process: protein transport (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.

Family and domain databases

InterPro

IPR004241; MAP1_LC3.
Graphical view of domain structure.

PANTHER

PTHR10969; MAP1_LC3; 1.

Pfam

PF02991; MAP1_LC3; 1.
Pfam graphical view of domain structure.

Genome annotation databases

Ensembl

ENSRNOG00000019425; Rattus norvegicus. [Contig view]
ENSRNOG00000033345; Rattus norvegicus. [Contig view]

GeneID

64670; -.

KEGG

rno:64670; -.

Phylogenomic databases

HOVERGEN

P60522; -.

Other

613665; -.

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Golgi apparatus; Phosphoprotein; Protein transport; Transport.

Features

Feature table viewer

Feature aligner

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 117`	`117`	`Gamma-aminobutyric acid receptor-associated protein-like 2.`	`PRO_0000212375`
`REGION`	`1 22`	`22`	`Interaction with beta-tubulin (By similarity).`
`REGION`	`36 68`	`33`	`Interaction with GABRG2 (Potential).`
`MOD_RES`	`10 10`		`Phosphoserine (By similarity).`
`MOD_RES`	`39 39`		`Phosphoserine (By similarity).`

Sequence information

Length: 117 AA [This is the length of the unprocessed precursor]

Molecular weight: 13667 Da [This is the MW of the unprocessed precursor]

CRC64: 17ACB540FD5B975B [This is a checksum on the sequence]

        10         20         30         40         50         60 
MKWMFKEDHS LEHRCVESAK IRAKYPDRVP VIVEKVSGSQ IVDIDKRKYL VPSDITVAQF 

        70         80         90        100        110 
MWIIRKRIQL PSEKAIFLFV DKTVPQSSLT MGQLYEKEKD EDGFLYVAYS GENTFGF

P60522 in FASTA format

View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools