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UniProtKB/Swiss-Prot entry P50275


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ASE1_YEAST
Primary accession number P50275
Secondary accession numbers None
Integrated into Swiss-Prot on October 1, 1996
Sequence was last modified on October 1, 1996 (Sequence version 1)
Annotations were last modified on    June 16, 2009 (Entry version 53)
Name and origin of the protein
Protein name Anaphase spindle elongation protein
Synonyms None
Gene name
Name: ASE1
OrderedLocusNames: YOR058C
ORFNames: YOR29-09
From
Saccharomyces cerevisiae (Baker's yeast) [TaxID: 4932] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1083/jcb.130.6.1373; PubMed=7559759 [NCBI, ExPASy, EBI, Israel, Japan]
Pellman D., Bagget M., Tu Y.H., Fink G.R.;
"Two microtubule-associated proteins required for anaphase spindle movement in Saccharomyces cerevisiae.";
J. Cell Biol. 130:1373-1385(1995).
[2]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1002/(SICI)1097-0061(19970330)13:4<379::AID-YEA85>3.3.CO;2-7; PubMed=9133743 [NCBI, ExPASy, EBI, Israel, Japan]
Valens M., Bohn C., Daignan-Fornier B., Dang V.-D., Bolotin-Fukuhara M.;
"The sequence of a 54.7 kb fragment of yeast chromosome XV reveals the presence of two tRNAs and 24 new open reading frames.";
Yeast 13:379-390(1997).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 96604 / S288c / FY1679;
PubMed=9169874 [NCBI, ExPASy, EBI, Israel, Japan]
Dujon B., Albermann K., Aldea M., Alexandraki D., Ansorge W., Arino J., Benes V., Bohn C., Bolotin-Fukuhara M., Bordonne R., Boyer J., Camasses A., Casamayor A., Casas C., Cheret G., Cziepluch C., Daignan-Fornier B., Dang V.-D., de Haan M., Delius H., Durand P., Fairhead C., Feldmann H., Gaillon L., Galisson F., Gamo F.-J., Gancedo C., Goffeau A., Goulding S.E., Grivell L.A., Habbig B., Hand N.J., Hani J., Hattenhorst U., Hebling U., Hernando Y., Herrero E., Heumann K., Hiesel R., Hilger F., Hofmann B., Hollenberg C.P., Hughes B., Jauniaux J.-C., Kalogeropoulos A., Katsoulou C., Kordes E., Lafuente M.J., Landt O., Louis E.J., Maarse A.C., Madania A., Mannhaupt G., Marck C., Martin R.P., Mewes H.-W., Michaux G., Paces V., Parle-McDermott A.G., Pearson B.M., Perrin A., Pettersson B., Poch O., Pohl T.M., Poirey R., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rechmann S., Schwager C., Schweizer M., Sor F., Sterky F., Tarassov I.A., Teodoru C., Tettelin H., Thierry A., Tobiasch E., Tzermia M., Uhlen M., Unseld M., Valens M., Vandenbol M., Vetter I., Vlcek C., Voet M., Volckaert G., Voss H., Wambutt R., Wedler H., Wiemann S., Winsor B., Wolfe K.H., Zollner A., Zumstein E., Kleine K.;
"The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.";
Nature 387:98-102(1997).
[4]
LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
DOI=10.1038/nature02046; PubMed=14562106 [NCBI, ExPASy, EBI, Israel, Japan]
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.;
"Global analysis of protein expression in yeast.";
Nature 425:737-741(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
U20235; AAA75026.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Z74966; CAA99251.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Z70678; CAA94543.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S59660; S59660.
RefSeq NP_116582.1; -.
3D structure databases
ModBase P50275.
Protein-protein interaction databases
DIP DIP:7343N; -.
IntAct P50275; 1.
Organism-specific databases
CYGD YOR058c; -.
SGD S000005584; ASE1.
Yeast-GFP YOR058C.
Gene expression databases
ArrayExpress P50275; -.
GermOnline YOR058C; Saccharomyces cerevisiae.
Ontologies
GO
GO:0005880; Cellular component: nuclear microtubule (inferred from direct assay from SGD).
GO:0051233; Cellular component: spindle midzone (inferred from direct assay from SGD).
GO:0008017; Molecular function: microtubule binding (inferred from direct assay from SGD).
GO:0007109; Biological process: cytokinesis, completion of separation (inferred from mutant phenotype from SGD).
GO:0001578; Biological process: microtubule bundle formation (inferred from direct assay from SGD).
GO:0000092; Biological process: mitotic anaphase B (inferred from mutant phenotype from SGD).
GO:0000022; Biological process: mitotic spindle elongation (inferred from mutant phenotype from SGD).
GO:0043148; Biological process: mitotic spindle stabilization (inferred from mutant phenotype from SGD).
GO:0051255; Biological process: spindle midzone assembly (inferred from mutant phenotype from SGD).
GO:0000073; Biological process: spindle pole body separation (inferred from genetic interaction from SGD).
QuickGo view.
Family and domain databases
InterPro IPR007145; MAP65_ASE1.
Graphical view of domain structure.
PANTHER PTHR19321; MAP65_ASE1; 1.
Pfam PF03999; MAP65_ASE1; 1.
Pfam graphical view of domain structure.
Genome annotation databases
Ensembl YOR058C; Saccharomyces cerevisiae. [Contig view]
GeneID 854223; -.
GenomeReviews Y13140_GR; YOR058C.
KEGG sce:YOR058C; -.
NMPDR fig|4932.3.peg.5801; -.
Phylogenomic databases
HOGENOM P50275; -.
OMA P50275; RNSHKIL.
Other
NextBio 976092; -.
ProtoNet P50275.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Microtubule.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   885  885     Anaphase spindle elongation protein. PRO_0000064694
Sequence information
Length: 885 AA [This is the length of the unprocessed precursor] Molecular weight: 101624 Da [This is the MW of the unprocessed precursor] CRC64: 6EDE11E887E89207 [This is a checksum on the sequence]
        10         20         30         40         50         60 
METATSSPLP IKSRRNSENS GSTTVIPHMN PSLATPLTVS TMVNQSNSKE FMKLTPVRIR 

        70         80         90        100        110        120 
DFGSPLKNVS TNYHFLDSEN GKGNTMDNMY RENFILISKD LEKLLENLNV IYQNIGYSNT 

       130        140        150        160        170        180 
EIITKEKIIF TTISNSIKQF FEQADEELKR LSAENGIEQD ILNNILERIN DPSGIKTIPD 

       190        200        210        220        230        240 
LYIRNAILLQ ESKTVPQSPK KPLSLLSKKA ALDTAKKFVL GSFLPRLRDY LKSLITLKHL 

       250        260        270        280        290        300 
IQSVKENLPG LTEADNEAIA EFPELSTLTA YLLQIENGKG DIGLSMKFII DNRKDILKGS 

       310        320        330        340        350        360 
AFKTINEESV KHMNEVIKIY EEEYERRFKS VLTKKVSISS ICEQLGTPLA TLIGEDFEQD 

       370        380        390        400        410        420 
LRSYGEEENS TSEIPNFHPV DRERMSKIDI TLEKLQAIHK ERADKKRLLM EQCQKLWTRL 

       430        440        450        460        470        480 
KISQEYIKTF MRNNSSLSTE SLGRISKEVM RLEAMKKKLI KKLISDSWDK IQELWRTLQY 

       490        500        510        520        530        540 
SEESRSKFII VFEELRNSAT TLQEDELLLE TCENELKRLE EKLTLYKPIL KLISDFESLQ 

       550        560        570        580        590        600 
EDQEFLERSS KDSSRLLSRN SHKILLTEEK MRKRITRHFP RVINDLRIKL EEADGLFDQP 

       610        620        630        640        650        660 
FLFKGKPLSE AIDIQQQEIE AKYPRCRVRM QRSKKGKCGA NKENKVIKNT FKATESSIRV 

       670        680        690        700        710        720 
PIGLNLNDAN ITYKTPSKKT IQGLTKNDLS QENSLARHMQ GTTKLSSPNR RATRLLAPTV 

       730        740        750        760        770        780 
ISRNSKGNIE RPTLNRNRSS DLSSSPRINH THGEHAVKPR QLFPIPLNKV DTKGSHIPQL 

       790        800        810        820        830        840 
TKEKALELLK RSTGTTGKEN VRSPERKSSL EDYAQKLSSP YKEPEHSIYK LSMSPEGKFQ 

       850        860        870        880 
LNIQQKDIES GFDDTSMMED ENDKDFITWK NEQVSKLNGF SFTDI 

P50275 in FASTA format

View entry in raw text format (no links)
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