[1]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND FUNCTION.
STRAIN=ATCC 26109 / X2180;
DOI=10.1038/26506; PubMed=9759731 [NCBI, ExPASy, EBI, Israel, Japan]
Mizushima N.,
Noda T.,
Yoshimori T.,
Tanaka Y.,
Ishii T.,
George M.D.,
Klionsky D.J.,
Ohsumi M.,
Ohsumi Y.;
"A protein conjugation system essential for autophagy.";
Nature 395:395-398(1998).
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[2]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 204511 / S288c / AB972;
DOI=10.1126/science.8091229; PubMed=8091229 [NCBI, ExPASy, EBI, Israel, Japan]
Johnston M.,
Andrews S.,
Brinkman R.,
Cooper J.,
Ding H.,
Dover J.,
Du Z.,
Favello A.,
Fulton L.,
Gattung S.,
Geisel C.,
Kirsten J.,
Kucaba T.,
Hillier L.W.,
Jier M.,
Johnston L.,
Langston Y.,
Latreille P.,
Louis E.J., ![]()
Macri C.,
Mardis E.,
Menezes S.,
Mouser L.,
Nhan M.,
Rifkin L.,
Riles L.,
St Peter H.,
Trevaskis E.,
Vaughan K.,
Vignati D.,
Wilcox L.,
Wohldman P.,
Waterston R.,
Wilson R.,
Vaudin M.;
"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII.";
Science 265:2077-2082(1994).
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[3]
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FUNCTION.
DOI=10.1016/0014-5793(93)80398-E; PubMed=8224160 [NCBI, ExPASy, EBI, Israel, Japan]
Tsukada M.,
Ohsumi Y.;
"Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae.";
FEBS Lett. 333:169-174(1993).
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[4]
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FUNCTION.
DOI=10.1083/jcb.131.3.591; PubMed=7593182 [NCBI, ExPASy, EBI, Israel, Japan]
Harding T.M.,
Morano K.A.,
Scott S.V.,
Klionsky D.J.;
"Isolation and characterization of yeast mutants in the cytoplasm to vacuole protein targeting pathway.";
J. Cell Biol. 131:591-602(1995).
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[5]
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FUNCTION, AND SUBCELLULAR LOCATION.
PubMed=10233148 [NCBI, ExPASy, EBI, Israel, Japan]
Kim J.,
Dalton V.M.,
Eggerton K.P.,
Scott S.V.,
Klionsky D.J.;
"Apg7p/Cvt2p is required for the cytoplasm-to-vacuole targeting, macroautophagy, and peroxisome degradation pathways.";
Mol. Biol. Cell 10:1337-1351(1999).
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[6]
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FUNCTION, SUBCELLULAR LOCATION, INTERACTION WITH ATG12, AND MUTAGENESIS OF GLY-333 AND CYS-507.
PubMed=10233150 [NCBI, ExPASy, EBI, Israel, Japan]
Tanida I.,
Mizushima N.,
Kiyooka M.,
Ohsumi M.,
Ueno T.,
Ohsumi Y.,
Kominami E.;
"Apg7p/Cvt2p: a novel protein-activating enzyme essential for autophagy.";
Mol. Biol. Cell 10:1367-1379(1999).
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[7]
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FUNCTION, INTERACTION WITH ATG8, AND MUTAGENESIS OF GLY-333 AND CYS-507.
DOI=10.1038/35044114; PubMed=11100732 [NCBI, ExPASy, EBI, Israel, Japan]
Ichimura Y.,
Kirisako T.,
Takao T.,
Satomi Y.,
Shimonishi Y.,
Ishihara N.,
Mizushima N.,
Tanida I.,
Kominami E.,
Ohsumi M.,
Noda T.,
Ohsumi Y.;
"A ubiquitin-like system mediates protein lipidation.";
Nature 408:488-492(2000).
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[8]
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HOMODIMERIZATION, AND INTERACTION WITH ATG3; ATG8 AND ATG12.
DOI=10.1074/jbc.M007737200; PubMed=11139573 [NCBI, ExPASy, EBI, Israel, Japan]
Komatsu M.,
Tanida I.,
Ueno T.,
Ohsumi M.,
Ohsumi Y.,
Kominami E.;
"The C-terminal region of an Apg7p/Cvt2p is required for homodimerization and is essential for its E1 activity and E1-E2 complex formation.";
J. Biol. Chem. 276:9846-9854(2001).
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[9]
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FUNCTION.
DOI=10.1083/jcb.152.1.51; PubMed=11149920 [NCBI, ExPASy, EBI, Israel, Japan]
Kim J.,
Huang W.-P.,
Klionsky D.J.;
"Membrane recruitment of Aut7p in the autophagy and cytoplasm to vacuole targeting pathways requires Aut1p, Aut2p, and the autophagy conjugation complex.";
J. Cell Biol. 152:51-64(2001).
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[10]
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NOMENCLATURE.
DOI=10.1016/S1534-5807(03)00296-X; PubMed=14536056 [NCBI, ExPASy, EBI, Israel, Japan]
Klionsky D.J.,
Cregg J.M.,
Dunn W.A. Jr.,
Emr S.D.,
Sakai Y.,
Sandoval I.V.,
Sibirny A.,
Subramani S.,
Thumm M.,
Veenhuis M.,
Ohsumi Y.;
"A unified nomenclature for yeast autophagy-related genes.";
Dev. Cell 5:539-545(2003).
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[11]
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FUNCTION.
DOI=10.1016/S0014-5793(03)00899-8; PubMed=12965207 [NCBI, ExPASy, EBI, Israel, Japan]
Yamazaki-Sato H.,
Tanida I.,
Ueno T.,
Kominami E.;
"The carboxyl terminal 17 amino acids within Apg7 are essential for Apg8 lipidation, but not for Apg12 conjugation.";
FEBS Lett. 551:71-77(2003).
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[12]
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FUNCTION, AND MUTAGENESIS OF CYS-507.
DOI=10.1074/jbc.M405860200; PubMed=15277523 [NCBI, ExPASy, EBI, Israel, Japan]
Ichimura Y.,
Imamura Y.,
Emoto K.,
Umeda M.,
Noda T.,
Ohsumi Y.;
"In vivo and in vitro reconstitution of atg8 conjugation essential for autophagy.";
J. Biol. Chem. 279:40584-40592(2004).
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