PROTEIN SEQUENCE.
TISSUE=Seed;
PubMed=3262509 [NCBI, ExPASy, EBI, Israel, Japan]
Casellas P., Dussossoy D., Falasca A.I., Barbieri L., Guillemot J.-C., Ferrara P., Bolognesi A., Cenini P., Stirpe F.;
"Trichokirin, a ribosome-inactivating protein from the seeds of Trichosanthes kirilowii Maximowicz. Purification, partial characterization and use for preparation of immunotoxins.";
Eur. J. Biochem. 176:581-588(1988).

Comments

CATALYTIC ACTIVITY: Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.
PTM: Glycosylated.
SIMILARITY: Belongs to the ribosome-inactivating protein family. Type 1 RIP subfamily.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

S01669; S01669.

3D structure databases

Ontologies

GO:0030598;	Molecular function: rRNA N-glycosylase activity (inferred from electronic annotation from EC).
GO:0006952;	Biological process: defense response (inferred from electronic annotation from UniProtKB-KW).
GO:0017148;	Biological process: negative regulation of translation (inferred from electronic annotation from UniProtKB-KW).
GO:0009405;	Biological process: pathogenesis (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.

Family and domain databases

PS00275; SHIGA_RICIN; PARTIAL.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Direct protein sequencing; Glycoprotein; Hydrolase; Plant defense; Protein synthesis inhibitor; Toxin.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 >16`	`>16`	`Ribosome-inactivating protein trichokirin.`	`PRO_0000221408`
`NON_TER`	`16 16`

Sequence information

Length: 16 AA [This is the length of the partial sequence of the unprocessed precursor]

Molecular weight: 1605 Da [This is the MW of the partial sequence of the unprocessed precursor]

CRC64: 5E268A7F345935A2 [This is a checksum on the sequence]

        10 
DVSFSLSGGG TASYEK

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools