ID   CRGA_BOVIN              Reviewed;         175 AA.
AC   P02527;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   17-APR-2007, sequence version 2.
DT   04-NOV-2008, entry version 56.
DE   RecName: Full=Gamma-crystallin A;
DE   AltName: Full=Gamma-A-crystallin;
DE   AltName: Full=Gamma-crystallin IVB;
GN   Name=CRYGA;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
OC   Pecora; Bovidae; Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   PROTEIN SEQUENCE OF 2-175.
RX   MEDLINE=73054483; PubMed=4674126;
RA   Croft L.R.;
RT   "The amino acid sequence of gamma-crystallin (fraction II) from calf
RT   lens.";
RL   Biochem. J. 128:961-970(1972).
CC   -!- FUNCTION: Crystallins are the dominant structural components of
CC       the vertebrate eye lens.
CC   -!- DOMAIN: Has a two-domain beta-structure, folded into four very
CC       similar Greek key motifs.
CC   -!- SIMILARITY: Belongs to the beta/gamma-crystallin family.
CC   -!- SIMILARITY: Contains 4 beta/gamma crystallin 'Greek key' domains.
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DR   HSSP; P02526; 1DSL.
DR   SMR; P02527; 2-175.
DR   HOVERGEN; P02527; -.
DR   GO; GO:0005212; F:structural constituent of eye lens; IEA:UniProtKB-KW.
DR   InterPro; IPR001064; Crystallin.
DR   Gene3D; G3DSA:2.60.20.10; Crystallin; 2.
DR   Pfam; PF00030; Crystall; 2.
DR   PRINTS; PR01367; BGCRYSTALLIN.
DR   SMART; SM00247; XTALbg; 2.
DR   PROSITE; PS50915; CRYSTALLIN_BETA_GAMMA; 4.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Eye lens protein; Repeat.
FT   INIT_MET      1      1       Removed.
FT   CHAIN         2    175       Gamma-crystallin A.
FT                                /FTId=PRO_0000057580.
FT   DOMAIN        2     40       Beta/gamma crystallin 'Greek key' 1.
FT   DOMAIN       41     83       Beta/gamma crystallin 'Greek key' 2.
FT   DOMAIN       89    129       Beta/gamma crystallin 'Greek key' 3.
FT   DOMAIN      130    172       Beta/gamma crystallin 'Greek key' 4.
FT   REGION       84     88       Connecting peptide.
SQ   SEQUENCE   175 AA;  21135 MW;  612258034CBF5BDF CRC64;
     MGKITFYEDR GFQGHCYQCS SNNCLQQPYF SRCNSIRVDV HSWFVYQRPD YRGHQYMLQR
     GNYPQYGQWM GFDDSIRSCR LIPQHTGTFR MRIYERDDFR GQMSEITDDC PSLQDRFHLT
     EVNSVRVLEG SWVIYEMPSY RGRQYLLRPG EYRRYLDWGA MNAKVGSLRR VMDFY
//