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[1]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1016/0092-8674(83)90306-9; PubMed=6301687 [NCBI, ExPASy, EBI, Israel, Japan]
van Beveren C.,
van Straaten F.,
Curran T.,
Mueller R.,
Verma I.M.;
"Analysis of FBJ-MuSV provirus and c-fos (mouse) gene reveals that viral and cellular fos gene products have different carboxy termini.";
Cell 32:1241-1255(1983).
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[2]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
PubMed=2991903 [NCBI, ExPASy, EBI, Israel, Japan]
Meijlink F.,
Curran T.,
Miller A.D.,
Verma I.M.;
"Removal of a 67-base-pair sequence in the noncoding region of protooncogene fos converts it to a transforming gene.";
Proc. Natl. Acad. Sci. U.S.A. 82:4987-4991(1985).
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[3]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=FVB/N;
TISSUE=Mammary gland;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
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[4]
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INTERACTION WITH DSIPI.
DOI=10.1074/jbc.M101522200; PubMed=11397794 [NCBI, ExPASy, EBI, Israel, Japan]
Mittelstadt P.R.,
Ashwell J.D.;
"Inhibition of AP-1 by the glucocorticoid-inducible protein GILZ.";
J. Biol. Chem. 276:29603-29610(2001).
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- FUNCTION: Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation.
- SUBUNIT: Heterodimer. Interacts with DSIPI; this interaction inhibits the binding of active AP1 to its target DNA. Interacts with MAFB (By similarity).
- SUBCELLULAR LOCATION: Nucleus.
- INDUCTION: C-fos expression increases upon a variety of stimuli, including growth factors, cytokines, neurotransmitters, polypeptide hormones, stress and cell injury.
- SIMILARITY: Belongs to the bZIP family. Fos subfamily.
- SIMILARITY: Contains 1 bZIP domain.
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Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms.
Distributed under the Creative Commons Attribution-NoDerivs License.
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| Length: 380 AA [This is the length of the unprocessed precursor] |
Molecular weight: 40838 Da [This is the MW of the unprocessed precursor] |
CRC64: 475966265952B624 [This is a checksum on the sequence] |
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10 20 30 40 50 60
MMFSGFNADY EASSSRCSSA SPAGDSLSYY HSPADSFSSM GSPVNTQDFC ADLSVSSANF
70 80 90 100 110 120
IPTVTAISTS PDLQWLVQPT LVSSVAPSQT RAPHPYGLPT QSAGAYARAG MVKTVSGGRA
130 140 150 160 170 180
QSIGRRGKVE QLSPEEEEKR RIRRERNKMA AAKCRNRRRE LTDTLQAETD QLEDEKSALQ
190 200 210 220 230 240
TEIANLLKEK EKLEFILAAH RPACKIPDDL GFPEEMSVAS LDLTGGLPEA STPESEEAFT
250 260 270 280 290 300
LPLLNDPEPK PSLEPVKSIS NVELKAEPFD DFLFPASSRP SGSETSRSVP DVDLSGSFYA
310 320 330 340 350 360
ADWEPLHSNS LGMGPMVTEL EPLCTPVVTC TPGCTTYTSS FVFTYPEADS FPSCAAAHRK
370 380
GSSSNEPSSD SLSSPTLLAL
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P01101 in FASTA format |
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ExPASy Home page
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