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UniProtKB/Swiss-Prot entry O87948

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name TORA_SHEMA
Primary accession number O87948
Secondary accession numbers None
Integrated into Swiss-Prot on July 15, 1999
Sequence was last modified on November 1, 1998 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 55)
Name and origin of the protein
Protein name Trimethylamine-N-oxide reductase [Precursor]
Synonyms TMAO reductase
Trimethylamine oxidase
EC 1.7.2.3
Gene name
Name: torA
From
Shewanella massilia [TaxID: 76854] 
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales; Shewanellaceae; Shewanella.
Protein existence 1: Evidence at protein level;
References
[1]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 32-61, AND INDUCTION.
DOI=10.1006/jmbi.1998.2155; PubMed=9813127 [NCBI, ExPASy, EBI, Israel, Japan]
Dos Santos J.P., Iobbi-Nivol C., Couillault C., Giordano G., Mejean V.;
"Molecular analysis of the trimethylamine N-oxide (TMAO) reductase respiratory system from a Shewanella species.";
J. Mol. Biol. 284:421-433(1998).
[2]
 X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS).
DOI=10.1006/jmbi.1998.2156; PubMed=9813128 [NCBI, ExPASy, EBI, Israel, Japan]
Czjzek M., Dos Santos J.P., Pommier J., Giordano G., Mejean V., Haser R.;
"Crystal structure of oxidized trimethylamine N-oxide reductase from Shewanella massilia at 2.5-A resolution.";
J. Mol. Biol. 284:435-447(1998).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AJ006085; CAA06851.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
3D structure databases
PDB
1TMO; X-ray; 2.50 A; A=1-829.[ExPASy / RCSB / EBI]
PDBsum 1TMO; -.
ModBase O87948.
Ontologies
GO
GO:0042597; Cellular component: periplasmic space (inferred from electronic annotation from InterPro).
GO:0009055; Molecular function: electron carrier activity (inferred from electronic annotation from InterPro).
GO:0030151; Molecular function: molybdenum ion binding (inferred from electronic annotation from InterPro).
GO:0050626; Molecular function: trimethylamine-N-oxide reductase (cytochrome c) activity (inferred from electronic annotation from InterPro).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR009010; Asp_de-COase-like_fold.
IPR006656; Mopterin_OxRdtase.
IPR006655; Mopterin_OxRdtase_prok_CS.
IPR006657; MPT_dinuc_bd.
IPR006311; Tat.
IPR011887; TorA.
Graphical view of domain structure.
Gene3D G3DSA:2.40.40.20; Asp_decarboxylase-like_fold; 1.
Pfam PF00384; Molybdopterin; 1.
PF01568; Molydop_binding; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR01409; TAT_signal_seq; 1.
TIGR02164; torA; 1.
PROSITE PS00551; MOLYBDOPTERIN_PROK_1; FALSE_NEG.
PS00490; MOLYBDOPTERIN_PROK_2; 1.
PS00932; MOLYBDOPTERIN_PROK_3; 1.
PS51318; TAT; 1.
PROSITE graphical view of domain structure (profiles).
ProtoNet O87948.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
3D-structure; Direct protein sequencing; Molybdenum; Oxidoreductase; Periplasm; Signal.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
SIGNAL   1    31  31     Tat-type signal. 
CHAIN   32   829  798     Trimethylamine-N-oxide reductase. PRO_0000019157
STRAND   41    45  5      
STRAND   48    55  8      
STRAND   58    64  7      
HELIX   73    76  4      
HELIX   78    82  5      
STRAND   92    94  3      
HELIX   95   100  6      
HELIX   101   103  3      
HELIX   106   108  3      
STRAND   113   116  4      
HELIX   119   136  18      
HELIX   139   141  3      
TURN   154   156  3      
HELIX   158   167  10      
STRAND   173   176  4      
STRAND   179   181  3      
HELIX   184   191  8      
HELIX   204   210  7      
STRAND   212   218  7      
HELIX   221   224  4      
STRAND   229   231  3      
HELIX   236   248  13      
STRAND   251   257  7      
HELIX   263   268  6      
STRAND   271   273  3      
HELIX   280   293  14      
HELIX   299   305  7      
HELIX   309   317  9      
TURN   318   321  4      
HELIX   327   334  8      
HELIX   338   350  13      
STRAND   353   357  5      
HELIX   360   362  3      
TURN   365   367  3      
HELIX   368   381  14      
STRAND   390   393  4      
TURN   398   401  4      
STRAND   435   438  4      
HELIX   439   441  3      
HELIX   442   447  6      
STRAND   452   454  3      
STRAND   456   461  6      
STRAND   467   472  6      
HELIX   475   478  4      
HELIX   482   489  8      
STRAND   493   501  9      
HELIX   504   507  4      
STRAND   510   515  6      
HELIX   518   520  3      
STRAND   523   527  5      
TURN   529   531  3      
STRAND   534   538  5      
HELIX   551   561  11      
HELIX   565   569  5      
HELIX   574   589  16      
TURN   590   592  3      
HELIX   598   604  7      
STRAND   606   608  3      
HELIX   619   623  5      
TURN   625   627  3      
STRAND   631   640  10      
HELIX   642   645  4      
STRAND   665   668  4      
TURN   669   673  5      
STRAND   676   679  4      
STRAND   684   687  4      
TURN   691   693  3      
HELIX   695   698  4      
TURN   699   701  3      
STRAND   708   711  4      
HELIX   713   718  6      
STRAND   726   730  5      
STRAND   735   742  8      
STRAND   750   752  3      
HELIX   769   772  4      
STRAND   777   780  4      
HELIX   783   785  3      
TURN   794   796  3      
STRAND   805   810  6      
STRAND   820   822  3      
Sequence information
Length: 829 AA [This is the length of the unprocessed precursor] Molecular weight: 92362 Da [This is the MW of the unprocessed precursor] CRC64: 6F58A59E8C41CF1F [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MNRRDFLKGI ASSSFVVLGG SSVLTPLNAL AKAGINEDEW LTTGSHFGAF KMKRKNGVIA 

        70         80         90        100        110        120 
EVKPFDLDKY PTDMINGIRG MVYNPSRVRY PMVRLDFLLK GHKSNTHQRG DFRFVRVTWD 

       130        140        150        160        170        180 
KALTLFKHSL DEVQTQYGPS GLHAGQTGWR ATGQLHSSTS HMQRAVGMHG NYVKKIGDYS 

       190        200        210        220        230        240 
TGAGQTILPY VLGSTEVYAQ GTSWPLILEH SDTIVLWSND PYKNLQVGWN AETHESFAYL 

       250        260        270        280        290        300 
AQLKEKVKQG KIRVISIDPV VTKTQAYLGC EQLYVNPQTD VTLMLAIAHE MISKKLYDDK 

       310        320        330        340        350        360 
FIQGYSLGFE EFVPYVMGTK DGVAKTPEWA APICGVEAHV IRDLAKTLVK GRTQFMMGWC 

       370        380        390        400        410        420 
IQRQQHGEQP YWMAAVLATM IGQIGLPGGG ISYGHHYSSI GVPSSGAAAP GAFPRNLDEN 

       430        440        450        460        470        480 
QKPLFDSSDF KGASSTIPVA RWIDAILEPG KTIDANGSKV VYPDIKMMIF SGNNPWNHHQ 

       490        500        510        520        530        540 
DRNRMKQAFH KLECVVTVDV NWTATCRFSD IVLPACTTYE RNDIDVYGAY ANRGILAMQK 

       550        560        570        580        590        600 
MVEPLFDSLS DFEIFTRFAA VLGKEKEYTR NMGEMEWLET LYNECKAANA GKFEMPDFAT 

       610        620        630        640        650        660 
FWKQGYVHFG DGEVWTRHAD FRNDPEINPL GTPSGLIEIF SRKIDQFGYD DCKGHPTWME 

       670        680        690        700        710        720 
KTERSHGGPG SDKHPIWLQS CHPDKRLHSQ MCESREYRET YAVNGREPVY ISPVDAKARG 

       730        740        750        760        770        780 
IKDGDIVRVF NDRGQLLAGA VVSDNFPKGI VRIHEGAWYG PVGKDGSTEG GAEVGALCSY 

       790        800        810        820 
GDPNTLTLDI GTSKLAQACS AYTCLVEFEK YQGKVPKVSS FDGPIEVEI
O87948 in FASTA format

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