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UniProtKB/Swiss-Prot entry O86034

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name BDHA_RHIME
Primary accession number O86034
Secondary accession numbers None
Integrated into Swiss-Prot on May 30, 2000
Sequence was last modified on November 1, 1998 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 55)
Name and origin of the protein
Protein name D-beta-hydroxybutyrate dehydrogenase
Synonyms BDH
EC 1.1.1.30
3-hydroxybutyrate dehydrogenase
3-HBDH
Gene name
Name: bdhA
OrderedLocusNames: RB1136
ORFNames: SMb21010
From
Rhizobium meliloti (Sinorhizobium meliloti) [TaxID: 382] [HAMAP proteome]
Encoded on Plasmid pSymB (megaplasmid 2).
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=SU47 / 1021;
PubMed=9922248 [NCBI, ExPASy, EBI, Israel, Japan]
Aneja P., Charles T.C.;
"Poly-3-hydroxybutyrate degradation in Rhizobium (Sinorhizobium) meliloti: isolation and characterization of a gene encoding 3-hydroxybutyrate dehydrogenase.";
J. Bacteriol. 181:849-857(1999).
[2]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=1021;
DOI=10.1073/pnas.161294698; PubMed=11481431 [NCBI, ExPASy, EBI, Israel, Japan]
Finan T.M., Weidner S., Wong K., Buhrmester J., Chain P., Vorhoelter F.J., Hernandez-Lucas I., Becker A., Cowie A., Gouzy J., Golding B., Puehler A.;
"The complete sequence of the 1,683-kb pSymB megaplasmid from the N2-fixing endosymbiont Sinorhizobium meliloti.";
Proc. Natl. Acad. Sci. U.S.A. 98:9889-9894(2001).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AF080548; AAD12733.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AL591985; CAC49536.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR H95983; H95983.
RefSeq NP_437676.1; -.
3D structure databases
HSSP Q10855; 1NFF. [HSSP ENTRY / PDB]
ModBase O86034.
Enzyme and pathway databases
BioCyc SMEL266834:SMB21010-MON; -.
Ontologies
GO
GO:0003858; Molecular function: 3-hydroxybutyrate dehydrogenase activity (inferred from electronic annotation from InterPro).
GO:0005488; Molecular function: binding (inferred from electronic annotation from InterPro).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR011294; 3-OHbutyrate_DHase.
IPR002198; DHase_sc/Rdtase_SDR.
IPR002347; Glc/ribitol_DHase.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR19410; ADH_short_C2; 1.
Pfam PF00106; adh_short; 1.
Pfam graphical view of domain structure.
PRINTS PR00081; GDHRDH.
PR00080; SDRFAMILY.
TIGRFAMs TIGR01963; PHB_DH; 1.
PROSITE PS00061; ADH_SHORT; 1.
ProtoNet O86034.
Genome annotation databases
GeneID 1237467; -.
GenomeReviews AL591985_GR; RB1136.
KEGG sme:SMb21010; -.
NMPDR fig|266834.1.peg.5771; -.
Phylogenomic databases
HOGENOM O86034; -.
Other
LinkHub O86034; -.
Genome annotation databases
CMR O86034; RB1136.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NAD; Oxidoreductase; Plasmid.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   258  258     D-beta-hydroxybutyrate dehydrogenase. PRO_0000054528
NP_BIND   6    30  25     NAD (By similarity). 
ACT_SITE   153   153        Proton acceptor (By similarity). 
BINDING   140   140        Substrate (By similarity). 
Sequence information
Length: 258 AA [This is the length of the unprocessed precursor] Molecular weight: 27179 Da [This is the MW of the unprocessed precursor] CRC64: ACE9D388A4F0D0BA [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MTKTAVITGS TSGIGLAIAR TLAKAGANIV LNGFGAPDEI RTVTDEVAGL SSGTVLHHPA 

        70         80         90        100        110        120 
DMTKPSEIAD MMAMVADRFG GADILVNNAG VQFVEKIEDF PVEQWDRIIA VNLSSSFHTI 

       130        140        150        160        170        180 
RGAIPPMKKK GWGRIINIAS AHGLVASPFK SAYVAAKHGI MGLTKTVALE VAESGVTVNS 

       190        200        210        220        230        240 
ICPGYVLTPL VEKQIPDQAR TRGITEEQVI NEVMLKGQPT KKFITVEQVA SLALYLAGDD 

       250 
AAQITGTHVS MDGGWTAQ
O86034 in FASTA format

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