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UniProtKB/Swiss-Prot entry O82210


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ANM12_ARATH
Primary accession number O82210
Secondary accession numbers None
Integrated into Swiss-Prot on July 10, 2007
Sequence was last modified on November 1, 1998 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 43)
Name and origin of the protein
Protein name Probable protein arginine N-methyltransferase 1.2
Synonym EC 2.1.1.-
Gene name
Name: PRMT1.2
OrderedLocusNames: At2g19670
ORFNames: F6F22.30
From
Arabidopsis thaliana (Mouse-ear cress) [TaxID: 3702] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
DOI=10.1038/45471; PubMed=10617197 [NCBI, ExPASy, EBI, Israel, Japan]
Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
Nature 402:761-768(1999).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=cv. Columbia;
DOI=10.1126/science.1088305; PubMed=14593172 [NCBI, ExPASy, EBI, Israel, Japan]
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
"Empirical analysis of transcriptional activity in the Arabidopsis genome.";
Science 302:842-846(2003).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=cv. Columbia;
Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K., Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.;
"Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
[4]
GENE FAMILY, AND NOMENCLATURE.
DOI=10.1016/j.pharmthera.2006.06.007; PubMed=17005254 [NCBI, ExPASy, EBI, Israel, Japan]
Krause C.D., Yang Z.H., Kim Y.S., Lee J.H., Cook J.R., Pestka S.;
"Protein arginine methyltransferases: evolution and assessment of their pharmacological and therapeutic potential.";
Pharmacol. Ther. 113:50-87(2007).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AC005169; AAC62148.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BT006491; AAP21299.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AK227449; BAE99452.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR F84579; F84579.
RefSeq NP_179557.1; -.
UniGene At.39807
3D structure databases
HSSP Q63009; 1ORH. [HSSP ENTRY / PDB]
ModBase O82210.
Protein-protein interaction databases
IntAct O82210; -.
Organism-specific databases
TAIR At2g19670; -.
Gene expression databases
ArrayExpress O82210; -.
Ontologies
GO
GO:0005634; Cellular component: nucleus (inferred from electronic annotation from UniProtKB-KW).
GO:0008168; Molecular function: methyltransferase activity (inferred from electronic annotation from UniProtKB-KW).
GO:0005515; Molecular function: protein binding (inferred from physical interaction from IntAct).
QuickGo view.
Family and domain databases
InterPro IPR013217; Methyltransf_12.
Graphical view of domain structure.
Pfam PF08242; Methyltransf_12; 1.
Pfam graphical view of domain structure.
ProtoNet O82210.
Genome annotation databases
GeneID 816486; -.
GenomeReviews CT485783_GR; AT2G19670.
KEGG ath:AT2G19670; -.
NMPDR fig|3702.1.peg.8961; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Methyltransferase; Nucleus; Transferase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   366  366     Probable protein arginine N-methyltransferase 1.2. PRO_0000293987
COMPBIAS   6     9  4     Poly-Asn. 
Sequence information
Length: 366 AA [This is the length of the unprocessed precursor] Molecular weight: 41172 Da [This is the MW of the unprocessed precursor] CRC64: 9C31A654BDCC4C70 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTSTENNNNG SDETQTTKLH FEDADESMHD GDDNNADVAD DITSADYYFD SYSHFGIHEE 

        70         80         90        100        110        120 
MLKDVVRTKS YQDVIYKNKF LIKDKIVLDV GAGTGILSLF CAKAGAAHVY AVECSQMADT 

       130        140        150        160        170        180 
AKEIVKSNGF SDVITVLKGK IEEIELPVPK VDVIISEWMG YFLLYENMLD TVLYARNKWL 

       190        200        210        220        230        240 
VDGGIVLPDK ASLYVTAIED AHYKDDKVEF WDDVYGFDMS CIKRRAITEP LVDTVDGNQI 

       250        260        270        280        290        300 
VTDSKLLKTM DISKMAAGDA SFTAPFKLVA QRNDHIHALV AYFDVSFTMC HKKMGFSTGP 

       310        320        330        340        350        360 
KSRATHWKQT VLYLEDVLTI CEGETITGSM TIAQNKKNPR DVDIKLSYSL NGQHCNISRT 


HFYKMR 

O82210 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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