ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry O43320


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name FGF16_HUMAN
Primary accession number O43320
Secondary accession numbers None
Integrated into Swiss-Prot on July 15, 1999
Sequence was last modified on June 1, 1998 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 59)
Name and origin of the protein
Protein name Fibroblast growth factor 16
Synonym FGF-16
Gene name
Name: FGF16
From
Homo sapiens (Human) [TaxID: 9606] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Heart;
DOI=10.1006/bbrc.1998.8073; PubMed=9473496 [NCBI, ExPASy, EBI, Israel, Japan]
Miyake A., Konishi M., Martin F.H., Hernday N.A., Ozaki K., Yamamoto S., Mikami T., Arakawa T., Itoh N.;
"Structure and expression of a novel member, FGF-16, on the fibroblast growth factor family.";
Biochem. Biophys. Res. Commun. 243:148-152(1998).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AB009391; BAA24956.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR JC5941; JC5941.
RefSeq NP_003859.1; -.
UniGene Hs.666364
3D structure databases
HSSP P31371; 1IHK. [HSSP ENTRY / PDB]
SMR O43320; 51-204.
ModBase O43320.
Enzyme and pathway databases
Reactome REACT_9470; Signaling by FGFR.
Organism-specific databases
H-InvDB HIX0056594; -.
HGNC HGNC:3672; FGF16.
GenAtlas FGF16.
MIM 603724; gene. [NCBI / EBI]
PharmGKB PA28111; -.
GeneCards O43320.
Gene expression databases
CleanEx HS_FGF16; -.
Ontologies
GO
GO:0005615; Cellular component: extracellular space (traceable author statement from ProtInc).
GO:0008083; Molecular function: growth factor activity (traceable author statement from ProtInc).
GO:0007267; Biological process: cell-cell signaling (traceable author statement from ProtInc).
GO:0008543; Biological process: fibroblast growth factor receptor signaling pathway (inferred from experiment from Reactome).
GO:0008152; Biological process: metabolic process (traceable author statement from ProtInc).
GO:0009887; Biological process: organ morphogenesis (traceable author statement from ProtInc).
GO:0009266; Biological process: response to temperature stimulus (traceable author statement from ProtInc).
QuickGo view.
Family and domain databases
InterPro IPR002209; GF_heparin_bd.
IPR002348; IL1_HBGF.
Graphical view of domain structure.
PANTHER PTHR11486; IL1_HBGF; 1.
Pfam PF00167; FGF; 1.
Pfam graphical view of domain structure.
PRINTS PR00263; HBGFFGF.
PR00262; IL1HBGF.
ProDom PD000831; IL1_HBGF; 1.
[Domain structure / List of seq. sharing at least 1 domain]
SMART SM00442; FGF; 1.
SMART graphical view of domain structure.
PROSITE PS00247; HBGF_FGF; 1.
BLOCKS O43320.
Genome annotation databases
Ensembl ENSG00000196468; Homo sapiens. [Contig view]
GeneID 8823; -.
KEGG hsa:8823; -.
Phylogenomic databases
HOVERGEN O43320; -.
Other
SOURCE FGF16; Homo sapiens.
ProtoNet O43320.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Glycoprotein; Growth factor; Secreted.
Features
SEVIEWER logo Feature table viewer
KeyFrom  To Length Description FTId
CHAIN   1   207  207     Fibroblast growth factor 16. PRO_0000147613
CARBOHYD   78    78        N-linked (GlcNAc...) (Potential). 
Sequence information
Length: 207 AA [This is the length of the unprocessed precursor] Molecular weight: 23759 Da [This is the MW of the unprocessed precursor] CRC64: D8AD160BDABDB5F8 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MAEVGGVFAS LDWDLHGFSS SLGNVPLADS PGFLNERLGQ IEGKLQRGSP TDFAHLKGIL 

        70         80         90        100        110        120 
RRRQLYCRTG FHLEIFPNGT VHGTRHDHSR FGILEFISLA VGLISIRGVD SGLYLGMNER 

       130        140        150        160        170        180 
GELYGSKKLT RECVFREQFE ENWYNTYAST LYKHSDSERQ YYVALNKDGS PREGYRTKRH 

       190        200 
QKFTHFLPRP VDPSKLPSMS RDLFHYR 

O43320 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
 Hosted by ca flag CBR Canada Mirror sites: Australia  Brazil  China  Korea  Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!