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UniProtKB/Swiss-Prot entry A8MEE1

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name AROE_ALKOO
Primary accession number A8MEE1
Secondary accession numbers None
Integrated into Swiss-Prot on February 5, 2008
Sequence was last modified on December 4, 2007 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 9)
Name and origin of the protein
Protein name Shikimate dehydrogenase
Synonym EC 1.1.1.25
Gene name
Name: aroE
OrderedLocusNames: Clos_0042
From
Alkaliphilus oremlandii (strain OhILAs) (Clostridium oremlandii (strain OhILAs)) [TaxID: 350688] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae; Alkaliphilus.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Stolz J.F., Dawson A., Fisher E., Crable B., Perera E., Lisak J., Ranganathan M., Basu P., Richardson P.;
"Complete genome of Alkaliphilus oremlandii OhILAs.";
Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000853; ABW17612.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_001511608.1; -.
3D structure databases
ModBase A8MEE1.
Ontologies
GO
GO:0004764; Molecular function: shikimate 5-dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0009073; Biological process: aromatic amino acid family biosynthetic process (inferred from electronic annotation from HAMAP).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
HAMAP MF_00222; -; 1.
PBIL [Tree]
InterPro IPR016040; NAD(P)-bd.
IPR011342; Quinate/shikimate_5-DHase.
IPR013708; Shikimate_DHase-bd_N.
IPR006151; Shikm_DHase/Glu-tRNA_Rdtase.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF01488; Shikimate_DH; 1.
PF08501; Shikimate_dh_N; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00507; aroE; 1.
BLOCKS A8MEE1.
ProtoNet A8MEE1.
Genome annotation databases
GeneID 5677725; -.
GenomeReviews CP000853_GR; Clos_0042.
KEGG aoe:Clos_0042; -.
CMR A8MEE1; Clos_0042.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Aromatic amino acid biosynthesis; Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   286  286     Shikimate dehydrogenase. PRO_1000058659
NP_BIND   133   137  5     NADP (By similarity). 
ACT_SITE   73    73        Proton acceptor (Potential). 
Sequence information
Length: 286 AA [This is the length of the unprocessed precursor] Molecular weight: 31523 Da [This is the MW of the unprocessed precursor] CRC64: B3141D5F0A3A85C9 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSYVITDETK LTGIIGRPIK QSFSPKIHNG AFQYLNLNYI YIPFEVVQQD LSKTVEAMKV 

        70         80         90        100        110        120 
LKFRGFNVTM PHKREVMNYL DEVSENAKII GAVNTVVNQN GKLVGHNTDG KGYVQSLEDE 

       130        140        150        160        170        180 
GIYVKEKTFV IAGAGGAARS VAVQLALDGA KKITILNRTI DKAHDIAQLI GMSIPNVHIE 

       190        200        210        220        230        240 
INCLENKTLA KAVEEADVLI NTTSLGMYSM EEESIIGEEK VLPSNLVVSD LIYNPAKTKL 

       250        260        270        280 
LQQAESRGCK TINGLGMLIG QAAIAFELWT EVAMPIDYIK KTLFTR
A8MEE1 in FASTA format

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