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UniProt Knowledgebase (Swiss-Prot and TrEMBL) Advanced Search

This search program uses SRS to perform queries. Simpler forms are available to search by description or by full text. Available connectors within a field are "&" (and), "|" (or) and "!" (but not). You can prefix your search terms by ! to specify "not" (this is not possible in SRS). Example queries:

To retrieve all AP1 complex proteins from mouse (AP1S1, AP1G1, etc. but not MIAP1, IQGAP1, ...), specify Gene Name: ap1*, Organism: Mus, and deselect "Append and prefix * to query terms".
To retrieve the three human beta-adrenergic receptor proteins in UniProtKB/Swiss-Prot, but not the beta-adrenergic receptor kinases, specify Description: beta&adrenergic&receptor!kinase, Organism: Homo sapiens, and select "Append and prefix * to query terms".

Search UniProtKB/Swiss-Prot UniProtKB/TrEMBL

	Description
	Gene name
AND	Organism
Append and prefix * to query terms
view of results

This tool can be used to create links to UniProtKB by using the URL of the results page.

The gory details:

The description line is indexed as a series of words. If no wildcard (*) is present at the start of the query, it will only match entries where the query is the start of the description. If no wildcard is present at the end of the query, it will only match entries where the query ends a word (so Ubiquitin will retrieve Ubiquitin carboxyl-terminal hydrolase 1 but not Ubiquitin-like protein). Here is an example of the output of a query when the "Append and prefix * to query terms" box is unchecked :

entry	description	Retrieved by the query...
entry	description	UBIQUITIN	UBIQUITIN*	UBIQUITIN
P02248	Ubiquitin	Yes	Yes	Yes
Q15843	Ubiquitin-like protein NEDD8	No	Yes	Yes
Q9NR09	Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon)	No	Yes	Yes
P55036	26S proteasome regulatory subunit S5A (Rpn10) (Multiubiquitin chain binding protein) (Antisecretory factor-1) (AF) (ASF)	No	No	Yes

The gene names are indexed as separate words.
The organism can be the latin name of a taxon (e.g. Mammalia) or of a species (e.g. Rana ridibunda). Beware of English names; for example Human will match human entries but also species such as Human Herpesvirus.

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