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The UniProtKB/Swiss-Prot Human Proteome Initiative
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HPI Status report

UniProtKB/Swiss-Prot Release 57.15 of 02-Mar-10: 515203 entries (Release statistics)

Total number of manually annotated mammalian entries in UniProtKB/Swiss-Prot: 64,838

Total number of manually annotated HUMAN entries in UniProtKB/Swiss-Prot: 20,265

Annotation categories counts [total / unique] max per entry average per entry number of entries coverage
Additional isoforms due to alternative splicing, initiation or promoter usage: 14,464 34 0.71 7,527 37%
Variants (disease mutations and polymorphisms): 62,195 1363 3.07 12,228 60%
Post-translational modifications (experimentally proven or potential): 78,681 304 3.88 12,926 63%
References to published articles: 132,555 / 49,720 183 6.54 20,151 99%
Comment blocks: 117,365 / 43,310 36 5.79 19,698 97%
Feature lines: 561,702 4286 27.72 20,265 100%
Cross-references:
EMBL protein_ids: 150,943 / 149,926 723 7.45 20,143 99%
InterPro: 60,141 / 7,798 24 2.97 17,294 85%
PDB (3D-structures): 35,087 / 32,902 548 1.73 3,935 19%
MIM catalog of human genes and genetic disorders: 15,806 / 14,912 15 0.78 12,440 61%
HGNC gene nomenclature: 19,528 / 19,397 14 0.96 19,356 95%

Total number of manually annotated MOUSE entries in UniProtKB/Swiss-Prot: 16,224

Annotation categories counts [total / unique] max per entry average per entry number of entries coverage
Additional isoforms due to alternative splicing, initiation or promoter usage: 7,478 20 0.46 4,422 27%
Variants (disease mutations and polymorphisms): 1,185 37 0.07 363 2%
Post-translational modifications (experimentally proven or potential): 65,497 217 4.04 11,114 68%
References to published articles: 54,898 / 18,810 50 3.38 16,100 99%
Comment blocks: 85,177 / 34,804 22 5.25 15,910 98%
Feature lines: 274,183 628 16.90 16,224 100%
Cross-references:
EMBL protein_ids: 72,441 / 72,386 111 4.47 16,088 99%
InterPro: 50,544 / 7,635 20 3.12 14,513 89%
PDB (3D-structures): 5,704 / 5,296 302 0.35 1,002 6%
Mouse Genome Informatics: 16,069 / 16,006 12 0.99 16,018 98%

Total number of manually annotated RAT entries in UniProtKB/Swiss-Prot: 7,483

Annotation categories counts [total / unique] max per entry average per entry number of entries coverage
Additional isoforms due to alternative splicing, initiation or promoter usage: 1,419 18 0.19 805 10%
Variants (disease mutations and polymorphisms): 275 30 0.04 116 1%
Post-translational modifications (experimentally proven or potential): 32,679 205 4.37 5,556 74%
References to published articles: 15,866 / 9,699 30 2.12 7,063 94%
Comment blocks: 39,612 / 19,096 26 5.29 7,372 98%
Feature lines: 119,789 315 16.01 7,483 100%
Cross-references:
EMBL protein_ids: 15,285 / 15,270 152 2.04 7,410 99%
InterPro: 24,575 / 5,587 20 3.28 6,816 91%
PDB (3D-structures): 3,267 / 3,111 164 0.44 437 5%
Rat Genome Database: 7,364 / 7,346 3 0.98 7,360 98%

For more detailed information about the taxonomic distribution of UniProtKB/Swiss-Prot entries, see the corresponding section in the Release statistics.