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The UniProtKB/Swiss-Prot Human Proteome Initiative
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HPI Status report

UniProtKB/Swiss-Prot Release 55.3 of 29-Apr-2008: 366226 entries (Release statistics)

Total number of manually annotated mammalian entries in UniProtKB/Swiss-Prot: 61,396

Total number of manually annotated HUMAN entries in UniProtKB/Swiss-Prot: 19,293

Annotation categories counts [total / unique] max per entry average per entry number of entries coverage
Additional isoforms due to alternative splicing, initiation or promoter usage: 12,793 32 0.66 6,762 35%
Variants (disease mutations and polymorphisms): 42,609 464 2.21 8,593 44%
Post-translational modifications (experimentally proven or potential): 56,695 303 2.94 10,728 55%
References to published articles: 97,103 / 43,422 165 5.03 19,076 98%
Comment blocks: 106,053 / 39,086 32 5.50 18,659 96%
Feature lines: 452,845 1429 23.47 19,293 100%
Cross-references:
EMBL protein_ids: 123,044 / 122,714 723 6.38 19,162 99%
InterPro: 47,464 / 6,421 23 2.46 16,269 84%
PDB (3D-structures): 24,784 / 23,354 444 1.28 3,135 16%
MIM catalog of human genes and genetic disorders: 14,949 / 14,081 15 0.77 11,938 61%
HGNC gene nomenclature: 18,353 / 18,226 14 0.95 18,235 94%

Total number of manually annotated MOUSE entries in UniProtKB/Swiss-Prot: 15,447

Annotation categories counts [total / unique] max per entry average per entry number of entries coverage
Additional isoforms due to alternative splicing, initiation or promoter usage: 6,788 20 0.44 4,043 26%
Variants (disease mutations and polymorphisms): 1,155 37 0.07 359 2%
Post-translational modifications (experimentally proven or potential): 47,201 216 3.06 9,118 59%
References to published articles: 44,842 / 16,764 49 2.90 15,221 98%
Comment blocks: 76,931 / 30,766 22 4.98 15,076 97%
Feature lines: 235,580 612 15.25 15,447 100%
Cross-references:
EMBL protein_ids: 65,329 / 65,280 111 4.23 15,308 99%
InterPro: 39,072 / 6,253 18 2.53 13,586 87%
PDB (3D-structures): 4,142 / 3,882 182 0.27 800 5%
Mouse Genome Informatics: 15,287 / 15,223 12 0.99 15,237 98%

Total number of manually annotated RAT entries in UniProtKB/Swiss-Prot: 6,979

Annotation categories counts [total / unique] max per entry average per entry number of entries coverage
Additional isoforms due to alternative splicing, initiation or promoter usage: 1,317 18 0.19 741 10%
Variants (disease mutations and polymorphisms): 237 12 0.03 112 1%
Post-translational modifications (experimentally proven or potential): 24,223 204 3.47 4,624 66%
References to published articles: 14,575 / 9,116 25 2.09 6,561 94%
Comment blocks: 35,629 / 17,033 24 5.11 6,843 98%
Feature lines: 102,164 314 14.64 6,979 100%
Cross-references:
EMBL protein_ids: 14,290 / 14,277 152 2.05 6,904 98%
InterPro: 18,625 / 4,545 17 2.67 6,314 90%
PDB (3D-structures): 2,528 / 2,413 114 0.36 380 5%
Rat Genome Database: 6,856 / 6,837 3 0.98 6,851 98%

For more detailed information about the taxonomic distribution of UniProtKB/Swiss-Prot entries, see the corresponding section in the Release statistics.

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