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HAMAP: Lactobacillus gasseri (strain ATCC 33323 / DSM 20243) complete proteome

General information

Species:  Lactobacillus gasseri (strain ATCC 33323 / DSM 20243)
Species code: LACGA
Taxonomy: Bacteria; Firmicutes; Lactobacillales; Lactobacillaceae; Lactobacillus (TaxID: 324831) [NEWT/ NCBI]
Description: Lactobacilli are normal inhabitants of the gastrointestinal tract of man and animals where they are widely considered to exert a number of beneficial roles including immunomodulation, interference with enteric pathogens, and maintenance of a healthy intestinal microflora. Historically, probiotic roles have been ascribed primarily to Lactobacillus acidophilus. The genus Lactobacillus presently comprises more than 50 recognized species of non pathogenic bacteria which in addition to their probiotic effects are useful to human as indispensable agents for the fermentation of foods and feed. Among these, Lactobacillus gasseri appears to represent the major homofermentative Lactobacillus species that occupies the human GI tract. This L. gasseri demonstrates good survival in the GI tract and has been associated with a variety of probiotic activities and roles including reduction of fecal mutagenic enzymes, adherence to intestinal tissues, stimulation of macrophages, and production of bacteriocins. Like other lactic acid bacteria, L.gasseri are acid tolerant, cannot synthesize porphyrins, and possess a strictly fermentative metabolism with lactic acid as the major metabolic end product (adapted from http://genome.jgi-psf.org/draft_microbes/lacga/lacga.home.html).
Properties: Presence of flagella: No
Human pathogen: No
Interaction: Animal commensal in Mammalia
Number of membranes: 1
Number of inteins:0
Statistics: Number of LACGA entries in the UniProt Knowledgebase: 1694 (213 in UniProtKB/Swiss-Prot + 1481 in UniProtKB/TrEMBL)


Genome(s) sequenced

Strain:    ATCC 33323 / DSM 20243
Genome structure:
Chromosome EMBL accession number CP000413 (circular; 1,894,360 bp) (download entry) (download Genome Reviews).
Reference(s):
[1] PubMed=17030793; [ NCBI , EBI , Israel , Japan ]
Makarova K.S., Slesarev A., Wolf Y.I., Sorokin A., Mirkin B., Koonin E.V., Pavlov A., Pavlova N., Karamychev V., Polouchine N., Shakhova V., Grigoriev I., Lou Y., Rohksar D., Lucas S., Huang K., Goodstein D.M., Hawkins T., Plengvidhya V., Welker D., Hughes J., Goh Y., Benson A., Baldwin K., Lee J.-H., Diaz-Muniz I., Dosti B., Smeianov V., Wechter W., Barabote R., Lorca G., Altermann E., Barrangou R., Ganesan B., Xie Y., Rawsthorne H., Tamir D., Parker C., Breidt F., Broadbent J.R., Hutkins R., O'Sullivan D., Steele J., Unlu G., Saier M.H. Jr., Klaenhammer T., Richardson P., Kozyavkin S., Weimer B.C., Mills D.A. ;
"Comparative genomics of the lactic acid bacteria.";
Proc. Natl. Acad. Sci. U.S.A. 103:15611-15616(2006).
Web links:
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid324831%5Borgn%5D
GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Lgas_ATCC33323
PEDANT: http://pedant.gsf.de:3345/pedant3htmlview/pedant3view?Method=start_method&Db=p3_p84_Lac_gasse
 EBI Proteome Analysis page



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