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HAMAP: Burkholderia mallei (strain NCTC 10247) complete proteome

General information

Species:  Burkholderia mallei (strain NCTC 10247)
Species code: BURM7
Taxonomy: Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; Burkholderiaceae; Burkholderia; pseudomallei group (TaxID: 320389) [NEWT/ NCBI]
Description: Burkholderia mallei is the etiologic agent of glanders, a disease that is often fatal. Its natural reservoir are horses and other equines, but it can be occasionally transmitted to humans either by inhalation or through breaks in the skin. It is an obligate animal pathogen, with an intracellular localization. B. mallei is highly infectious as an aerosol and was used as a biological weapon in the American Civil War and in both World Wars. Unlike the related bacterium B.pseudomallei it is non-motile. One of its virulence factors has been identified as the type III secretion system, another as the newly characterized type VI (T6S). Strain NCTC 10247 will be used for comparative genomics.
Properties: Presence of flagella: No
Human pathogen: Yes
Interaction: Animal pathogen in Mammalia (intracellular obligate)
Number of membranes: 2
Number of inteins:0
Statistics: Number of BURM7 entries in the UniProt Knowledgebase: 5182 (356 in UniProtKB/Swiss-Prot + 4826 in UniProtKB/TrEMBL)


Genome(s) sequenced

Strain:    NCTC 10247
Genome structure:
• Chromosome I EMBL accession number CP000547 (circular; 2,352,693 bp) (download entry) (download Genome Reviews).
• Chromosome II EMBL accession number CP000548 (circular; 3,495,687 bp) (download entry) (download Genome Reviews).
Reference(s):
[1] DeShazer D., Woods D.E., Nierman W.C. ;
Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
Web links:
Official genome site(s):
http://msc.tigr.org/b_mallei/burkholderia_mallei_nctc_10247/genbank.shtml
Other web sites:
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&cmd=ShowDetailView&TermToSearch=13946
GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Bmal_NCTC10247
Pathema: http://pathema.tigr.org/tigr-scripts/Burkholderia/GenomePage.cgi?org=gbm4
 EBI Proteome Analysis page



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