Species code:	BRUAB
Taxonomy:	Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Brucellaceae; Brucella (TaxID: 235) [NEWT/ NCBI]
Description:	Brucellosis is a major infectious disease for both human and animals. Several Brucella species (B.abortus, B.melitensis and B.suis) have been isolated from many different animals. All three Brucella species cause a severe human disease characterized in its acute phase by undulant fever and in its chronic phase by damage of different organs. Brucellosis is a major problem in the Mediterranean region and parts of Asia, Africa and Latin America. When the infection is localized to the brain or the heart, it can result in a fatal meningitidis or fatal endocarditis, respectively. Brucella abortus is responsible not only for the human affection but also for the brucellosis of cattle, also known as "contagious abortion". Brucella abortus infection in cattle is responsible for abortion or premature calving. The foetus, placenta and uterine fluid contain large quantities of bacteria which can infect other cattle. The organism continues to be excreted in the milk; in the past humans were frequently infected through drinking unpasteurised milk. Human brucellosis is treatable with antibiotics whereas animals can be vaccinated. Although Brucellae contain a large set of flagellar genes, they display a species-specific gene inactivation and consequently are nonmotile.
Properties:	Presence of flagella: No Interaction: Animal pathogen in Mammalia Number of membranes: 2 Number of inteins:0
Statistics:	Number of BRUAB entries in the UniProt Knowledgebase: 3077 (493 in UniProtKB/Swiss-Prot + 2584 in UniProtKB/TrEMBL)

Genome structure:	• Chromosome I EMBL accession number AE017223 (circular; 2,124,241 bp) (download entry) (download Genome Reviews). • Chromosome II EMBL accession number AE017224 (circular; 1,162,204 bp) (download entry) (download Genome Reviews).
Reference(s):	[1] PubMed=15805518; [ NCBI , EBI , Israel , Japan ] Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C. ; "Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis."; J. Bacteriol. 187:2715-2726(2005).
Web links:	CBS: http://www.cbs.dtu.dk/services/GenomeAtlas/show-genus.php?kingdom=Bacteria&GLgenus=Brucella&GLspecies=abortus&GLstrain=9-941 Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid262698%5Borgn%5D GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Babo_BIOVAR1_9941 Karyn's Genomes: http://www.ebi.ac.uk/2can/genomes/bacteria/Brucella_abortus.html PATRIC: http://patric.vbi.vt.edu/genome/overview.php?genomeId=9 PEDANT: http://pedant.gsf.de:3345/pedant3htmlview/pedant3view?Method=start_method&Db=p3_p9619_Bru_abort RhizoDB: http://xbase.bham.ac.uk/rhizodb/genome.pl?id=966 TIGR CMR: http://cmr.tigr.org/tigr-scripts/CMR/GenomePage.cgi?database=ntba06  EBI Proteome Analysis page  UniProtKB/Swiss-Prot document

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