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NiceZyme View of ENZYME: EC 2.7.7.7

Official Name
DNA-directed DNA polymerase.
Alternative Name(s)
DNA nucleotidyltransferase (DNA-directed).
DNA-dependent DNA polymerase.
Reaction catalysed
Deoxynucleoside triphosphate + DNA(n) <=> diphosphate + DNA(n+1)
Comment(s)
  • Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time.
  • Cannot initiate a chain de novo.
  • Requires a primer which may be DNA or RNA.
  • See also EC 2.7.7.49.
Cross-references
Biochemical Pathways; map number(s)I1 ; J1 ; I2 ; J2 ; L7 ; O7 ; Q7 ; R8 ; S8 ; S9
PROSITEPDOC00107 ; PDOC00412 ; PDOC00452
BRENDA2.7.7.7
PUMA22.7.7.7
PRIAM enzyme-specific profiles2.7.7.7
KEGG Ligand Database for Enzyme Nomenclature2.7.7.7
IUBMB Enzyme Nomenclature2.7.7.7
IntEnz2.7.7.7
MEDLINEFind literature relating to 2.7.7.7
MetaCyc2.7.7.7

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