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NiceZyme View of ENZYME: EC 2.4.2.8

Accepted Name
Hypoxanthine phosphoribosyltransferase.
Alternative Name(s)
Guanine phosphoribosyltransferase.
HGPRTase.
Hypoxanthine-guanine phosphoribosyltransferase.
IMP diphosphorylase.
IMP pyrophosphorylase.
Transphosphoribosidase.
Reaction catalysed
IMP + diphosphate <=> hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate
Comment(s)
Guanine and 6-mercaptopurine can replace hypoxanthine.
Cross-references
Biochemical Pathways; map number(s)G1 ; G2
PROSITEPDOC00096
BRENDA2.4.2.8
EC2PDB2.4.2.8
PRIAM enzyme-specific profiles2.4.2.8
KEGG Ligand Database for Enzyme Nomenclature2.4.2.8
IUBMB Enzyme Nomenclature2.4.2.8
IntEnz2.4.2.8
MEDLINEFind literature relating to 2.4.2.8
MetaCyc2.4.2.8
UniProtKB/Swiss-Prot
O66821, HPRT_AQUAE;  P37472, HPRT_BACSU;  Q3SZ18, HPRT_BOVIN;  
P57291, HPRT_BUCAI;  Q8K9U8, HPRT_BUCAP;  Q6WIT9, HPRT_CANFA;  
Q9W719, HPRT_CHICK;  Q27541, HPRT_CRIFA;  P00494, HPRT_CRIGR;  
Q54NJ8, HPRT_DICDI;  P0A9M3, HPRT_ECOL6;  P0A9M2, HPRT_ECOLI;  
Q839B2, HPRT_ENTFA;  P45078, HPRT_HAEIN;  P00492, HPRT_HUMAN;  
Q02522, HPRT_LACLA;  P43152, HPRT_LEIDO;  Q6LDD9, HPRT_MACFA;  
P47959, HPRT_MERUN;  P00493, HPRT_MOUSE;  Q64531, HPRT_MUSSP;  
P96794, HPRT_MYCAV;  P0A5T1, HPRT_MYCBO;  P47696, HPRT_MYCGE;  
O69537, HPRT_MYCLE;  P75119, HPRT_MYCPN;  P0A5T0, HPRT_MYCTU;  
A5A6I1, HPRT_PANTR;  Q45FY6, HPRT_PIG;  P27605, HPRT_RAT;  
P37171, HPRT_RHOCA;  O33799, HPRT_SALTY;  P09383, HPRT_SCHMA;  
P0A9M4, HPRT_SHIFL;  Q5HIG5, HPRT_STAAC;  P65827, HPRT_STAAM;  
P99085, HPRT_STAAN;  Q6GJG1, HPRT_STAAR;  Q6GBX8, HPRT_STAAS;  
P65828, HPRT_STAAW;  Q5HRP4, HPRT_STAEQ;  Q8CQV4, HPRT_STAES;  
Q8E7Y1, HPRT_STRA3;  Q8E2H3, HPRT_STRA5;  Q8DWM8, HPRT_STRMU;  
Q8P321, HPRT_STRP3;  Q5XEL6, HPRT_STRP6;  Q7CNQ9, HPRT_STRP8;  
Q97TC4, HPRT_STRPN;  Q8DRP8, HPRT_STRR6;  Q5M216, HPRT_STRT1;  
Q5M6K8, HPRT_STRT2;  Q07010, HPRT_TRYBB;  P18134, HPRT_VIBHA;  
Q04178, HPRT_YEAST;  Q92F56, TILS_LISIN;  Q724J4, TILS_LISMF;  
Q8YAC7, TILS_LISMO;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-