| Official Name |
|---|
| Methylenetetrahydrofolate reductase (ferredoxin).
|
| Alternative Name(s) |
|---|
| 5,10-methylenetetrahydrofolate reductase. |
| Reaction catalysed |
|---|
| 5-methyltetrahydrofolate + 2 oxidized ferredoxin <=> 5,10-methylenetetrahydrofolate + 2 reduced ferredoxin + 2 H(+) |
| Cofactor(s) |
|---|
| Flavoprotein; Iron-sulfur; Zinc.
|
| Comment(s) |
|---|
- The enzyme from Clostridium formicoaceticum catalyzes the reduction
of methylene blue, menadione, benzyl viologen, rubredoxin or FAD with
5-methyltetrahydrofolate and the oxidation of reduced ferredoxin or
FADH(2) with 5,10-methylenetetrahydrofolate.
- However, unlike EC 1.5.1.20, there is no activity with NAD(P)H.
|
| Cross-references |
|---|
| BRENDA | 1.5.7.1 |
| PUMA2 | 1.5.7.1 |
| PRIAM enzyme-specific profiles | 1.5.7.1 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.5.7.1 |
| IUBMB Enzyme Nomenclature | 1.5.7.1 |
| IntEnz | 1.5.7.1 |
| MEDLINE | Find literature relating to 1.5.7.1 |
| MetaCyc | 1.5.7.1 |
ExPASy Home page