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ENZYME

ENZYME entry: EC 1.1.1.149

Accepted Name
20alpha-hydroxysteroid dehydrogenase
Reaction catalysed
  • (17R,20S)-17,20-dihydroxypregn-4-en-3-one + NAD(+) <=> 17alpha-hydroxyprogesterone + H(+) + NADH
  • (17R,20S)-17,20-dihydroxypregn-4-en-3-one + NADP(+) <=> 17alpha-hydroxyprogesterone + H(+) + NADPH
Comment(s)
Re-specific with respect to NAD(P)(+) (cf. EC 1.1.1.62).
Cross-references
BRENDA1.1.1.149
EC2PDB1.1.1.149
ExplorEnz1.1.1.149
PRIAM enzyme-specific profiles1.1.1.149
KEGG Ligand Database for Enzyme Nomenclature1.1.1.149
IUBMB Enzyme Nomenclature1.1.1.149
IntEnz1.1.1.149
MEDLINEFind literature relating to 1.1.1.149
MetaCyc1.1.1.149
Rhea expert-curated reactions1.1.1.149
UniProtKB/Swiss-Prot
P35430, AHD2_TETPYQ04828, AK1C1_HUMANQ95JH7, AK1C1_MACFA
Q95JH6, AK1C1_MACFUQ5REQ0, AK1C1_PONABQ8K023, AKC1H_MOUSE
P51652, AKC1H_RATP80508, PE2R_RABIT

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